Blueprint to Close the Women%E2%80%99s Health Gap 2025

Introduction This report and the accompanying Women’s Health Impact Tracking (WHIT) Platform provide data- driven insights that track progress to close the women’s health gap, in terms of gaps across care delivery, treatment efficacy and data availability. In the 2024 report, Closing the Women’s Health Gap: A $1 Trillion Opportunity to Improve Lives and Economies, 64 conditions were identified that affect women uniquely, differently or disproportionately to men and account for almost 86% of the global disease burden among women. To effectively address the gaps in care delivery, treatment efficacy, data availability and investment across these conditions, a phased approach was adopted. In the first year, nine conditions were selected using a framework that assessed their potential impact on women’s lives and their broader economic impact, among other criteria. Process and outcome data for each condition was collected at a global level, and when data was unavailable, country-level data was tracked in 15 selected countries and impact- tracking metrics were subsequently defined. This appendix provides the detailed methodologies, frameworks and data sources underpinning these efforts, ensuring transparency and enabling future application of the insights presented. Selection of high- impact conditions selected for year 1, countries and metrics1 A selection framework identified nine women’s health conditions that, collectively, account for one- third of the overall women’s health gap and are the focus of the first edition of the WHIT platform. The following criteria guided the selection: –Global burden of disease measured in disability- adjusted life years (DALYs) –Economic impact measured in terms of potential change in GDP (estimated by the supply-side benefits from having a larger, healthier and more productive female labour force, which were used to project the annual potential GDP contribution to 2040)191 –Prevalence rate measured in rate per 100,000 population –Incidence rate measured in rate per 100,000 population –Burden and GDP impact in lower-middle- income countries (LMICs) and low-income countries (LICs) –Global Alliance for Women’s Health members’ expert recommendations Each criterion was given a different weighting depending on the potential to build a compelling investment case for addressing women’s health disparities: global burden, GDP impact, Alliance members’ expert recommendations all scored a 1 on relative relevance; prevalence rate and incidence rate scored a 2; and then LMIC and LIC burden and GDP impact scored a 3. For each criterion, conditions were ranked from lowest to highest across the 64 conditions, and each rank was multiplied by the allocated weight for the criteria. These seven criteria formed a composite score to rank the conditions as follows. Please refer to Figure 1 in the report for details.1.1 Selected conditions Blueprint to Close the Women’s Health Gap: How to Improve Lives and Economies for All 36