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CHIKUNGUNYA VACCINES
Beth Bell, MD, MPH
Chair, ACIP Chikungunya Vaccines Work GroupACIP Meeting
October 26, 2023
Background
Expected licensure date for Valneva’s chikungunya vaccine revised from
August 2023 to November 2023
No chikungunya vaccine ever licensed in United States or globally
No existing ACIP chikungunya vaccine recommendations
Chikungunya Vaccines Work Group is developing policy options for ACIP’s consideration for use of chikungunya vaccine among U.S. persons at risk of
chikungunya, including
–Travelers
–Laboratory workers
–Residents of U.S. territories and states with, or at risk of, transmission
Recap of previous Work Group presentations to ACIP
October 2022
–Overview of chikungunya virus disease and vaccines
–Immunogenicity and safety of Valneva’s chikungunya vaccine
February 2023
–Global epidemiology of chikungunya
–Chikungunya among U.S. travelers
–Persistent arthralgia following chikungunya
June 2023
–Value of a vaccine to U.S. travelers
–Chikungunya virus infection among laboratory workers
–Observations on a large chikungunya outbreak in Paraguay
Overview of today’s session
Evidence to Recommendations for chikungunya vaccine use among U.S.
travelers*
–Dr. Susan Hills (CDC/NCEZID)
Evidence to Recommendations for chikungunya vaccine use among
laboratory workers*
–Dr. Susan Hills (CDC/NCEZID)
*Anticipated vote at February 2024 ACIP meeting if vaccine is licensed
ACIP Ex Officio Invited Consultants
Beth Bell, Univ Washington (Chair) Robin Levis, FDA Alan Barrett, Univ Texas Galveston
Wilbur Chen, Univ Maryland Sixun Yang, FDA Carina Blackmore, Florida Dept Health
Lesley Dupuy, NIH Alan Lam, DoD
CDC Leads Margaret Ryan, DoD
Susan Hills, DVBD (Lead) ACIP Liaisons Steven Schofield, CATMAT
Nicole Lindsey, DVBD (Deputy Lead) Elizabeth Barnett, ISTM David Shlim, Jackson Hole Travel & Trop Med
James Campbell, AAP Nestor Sosa, Uni New Mexico Hospital
Mary Pat Friedlander, AAFP Sanet Torres, San Jorge Children & Women's Hospital
Saroj Rai, AIM Kirsten Vannice, Bill & Melinda Gates Foundation
Mary Wilson, Univ California San FranciscoChikungunya Vaccines Work Group members
DVBD DGMQ ISD
Erin Staples Sarah Guagliardo Elisabeth Velazque z
Ann Powers
Laura Adams DHQP GRADE/ETR consultants
Joshua Wong Michael McNeil Doug Campos -Outcalt
Rebecca Morgan
NCEZID GID
Rita Helfand Rebecca Casey ACIP Secretariat
Jessica MacNeil, NCIRD
Leslie Lee, NCIRDChikungunya Vaccines Work Group CDC participants