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Principal Investigator: SOHAIL Imran KHAN
Organization: CHEROKEE NATION
Fiscal Year: 2024
Award: $1,327,535
Funding agency: National Institute of General Medical Sciences
Project Summary
Major health inequities continue to impact tribal nations, yet a serious shortage of scientists who conduct tribally
engaged research aimed at alleviating health disparities affecting American Indian (AI) people persists. For
several years, Cherokee Nation, the University of Oklahoma (OU) system and the Oklahoma Medical Research
Foundation (OMRF) have partnered to address this issue by building tribal research capacity through the Native
American Research Centers for Health (NARCH) mechanism. In this cycle of NARCH funding, the partnership
among Cherokee Nation, OU and OMRF continues and, importantly for student career enhancement, expands
to include the Oklahoma State University (OSU) system as a key partner for student career enhancement
activities. The overall mission of Cherokee Nation NARCH is to develop durable research capacity within the
context of a Native American tribal nation to address health inequities affecting the AI population of northeastern
Oklahoma. To achieve this goal, the five Specific Aims of Cherokee Nation NARCH are:
1. to strengthen administrative infrastructure, including a Leadership Team (LT) and a Tribal-Campus
Advisory Committee (TCAC), that ensures integration of career enhancement, capacity building and research
activities;
2. to educate the next generation of researchers to engage meaningfully with Cherokee Nation in the context
of tribal research, focusing on undergraduate, graduate and health professions students;
3. to build tribal capacity by developing a set of research codes to govern the conduct of genomic and other
biomedical research predicated on the concept of tribal data sovereignty;
4. to conduct innovative research capable of seeding future research projects performed by researchers
seeking to work within the Cherokee Nation setting; and
5. to evaluate activities of the partnership, including monitoring progress of student career enhancement,
capacity building, and research projects, and evaluation of the overall Cherokee Nation NARCH program.
Cherokee Nation NARCH provides a crucial opportunity to solidify the foundation for tribal capacity in health
disparities research. The addition of OSU strengthens this project, as OSU has demonstrated remarkable
success in the education of AI students in scientific and health professions fields, including the advent of the first
tribally affiliated medical school in the US. Cherokee Nation NARCH therefore provides an unprecedented
environment in which a Tribe, two research-intensive universities with large NA student populations (OU and
OSU), and a biomedical research foundation (OMRF) will work synergistically to reduce the unacceptable
disparities in health that continue to affect AI people.
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disease rate><Musculoskeletal Pain Disorder><NARCH><Native American Research Center for Health><Native American Tribe><Native Americans><Oklahoma><Patients><Population><Psychologist><Psychology><Public Health><R-Series Research Projects><R01 Mechanism><R01 Program><Research><Research Activity><Research Grants><Research Personnel><Research Project Grants><Research Projects><Researchers><Reservations><Rheumatic Diseases><Rheumatism><Rheumatoid Arthritis><Rheumatologic Diseases><Rheumatologic Disorder><Rheumatology><SLE><Scientist><Scleroderma><Severity of illness><Students><System><Systemic Lupus Erythematosus><Systemic Lupus Erythematous><Systemic Lupus Erythmatosus><Task Forces><Training><Tribal Participatory Research><Tribally Based Participatory Research><Tribally-driven participatory research><Tribes><United States Indian Health Service><Universities><Work><access to health care><access to healthcare><accessibility of health care><accessibility to health care><accessibility to healthcare><advisory team><care facilities><career><career development><chronic COVID><chronic COVID-19><chronic effect of COVID-19><chronic novel coronavirus disease 2019><co-morbid><co-morbidity><comorbidity><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><dermatosclerosis><disease severity><disparity in health><disseminated lupus erythematosus><early detection><early therapy><environmental risk><ethical legal and social><ethical, legal, and social implication><experience><health application><health care access><health care availability><health care service access><health care service availability><health disparities science><health disparity><health inequalities><health science profession><healthcare access><healthcare accessibility><healthcare availability><healthcare service access><healthcare service availability><improved><innovate><innovation><innovative><interest><long haul COVID><long haul COVID-19><long haul coronavirus disease><long haul coronavirus disease 2019><long term consequences of COVID-19><long term consequences of SARS-CoV-2 infection><long term consequences of coronavirus disease-19><long term effects of COVID-19><long term health consequences of COVID-19><long term health consequences of SARS-CoV2 infection><long term impact of COVID-19><long term impact of SARS-CoV-2 infection><long-hauler COVID><long-hauler COVID-19><long-hauler coronavirus disease 2019><long-hauler syndrome><long-term COVID><long-term COVID-19><long-term consequence of severe acute respiratory distress syndrome-cov-2 infection><long-term coronavirus disease><long-term coronavirus disease 2019><long-term effects of coronavirus disease-19><longterm COVID><longterm COVID-19><longterm consequences of COVID-19><longterm consequences of SARS-CoV-2 infection><longterm coronavirus disease><longterm coronavirus disease 2019><longterm effects of COVID-19><longterm health consequences of COVID-19><longterm health consequences of SARS-CoV2 infection><longterm impact of COVID-19><longterm impact of SARS-CoV-2 infection><medical college><medical schools><mortality><nation reservation><native american reservation><natives><next generation><persistent COVID-19><post COVID syndrome><post COVID-19 syndrome><post acute COVID syndrome><post acute COVID-19><post acute COVID-19 syndrome><post acute SARS-CoV-2><post acute coronavirus disease 2019><post acute coronavirus disease 2019 syndrome><post acute coronavirus disease syndrome><post acute severe acute respiratory syndrome coronavirus 2><post coronavirus disease 2019 syndrome><post coronavirus disease syndrome><post-acute phases of COVID-19><primary care provider><programs><prolonged COVID-19 symptoms><providers from primary care><providers of primary care><reservation community><rheumatic arthritis><school of medicine><student engagement><student motivation><student participation><success><systemic autoimmune disease><systemic autoimmune disorder><systemic lupus erythematosis><tribal Nation><tribal governance><tribal government><tribal member><tribal reservation><tribal self-governance><tribally engaged research><tribally led research><tribally-driven research><undergrad><undergraduate><undergraduate student>