Document text
Principal Investigator: Alexander Bukreyev
Organization: UNIVERSITY OF TEXAS MED BR GALVESTON
Fiscal Year: 2022
Award: $361,188
Funding agency: National Institute of Allergy and Infectious Diseases
ADMINISTRATIVE CORE (Core A): PROJECT SUMMARY/ABSTRACT
The Administrative Core is responsible for the strategic planning, overall management, and coordination of the
Program Project (P01) “Molecular Mechanisms of the Dysregulated Immune Response to Ebola Virus”. It
provides governance, financial oversight, and operational management functions to facilitate the execution of
the overall research plan, thereby enabling the Program to fulfill its mission to characterize the transcriptional,
posttranscriptional, and posttranslational mechanisms following Ebola virus infection that lead to the
dysregulated immune response. The Administrative Core will provide an organizational and programmatic
structure to promote research productivity and synergy through scientific interactions. The Core will provide
oversight in setting priorities, including decision-making processes involving the continual evaluation of research
by the PIs and an advisory board. Core personnel will ensure that the Program includes biostatistical rigor and
is compliant with issues involving the use of vertebrate animals, select agents, and BSL-4 facilities, and will
ensure that regulatory expertise is available for future product development activities. Management activities are
carried out with the advice of the External Advisory Committee in close collaboration with Core leadership.
Emails, teleconferencing, and videoconferencing are maximally utilized to facilitate communication between the
University of Texas Medical Branch, the lead institution for the P01, and participating institutions.
Terms: <Address><Administrator><Advisory Committees><BSL-4 facility><BSL4 facility><Biometrics><Biometry><Biostatistics><Children's Hospital><Clinical Management><Collaborations><Communication><Containment><Core Facility><Coronaviridae><Coronavirus><Data><Decision Making><Dengue><Development><E-Mail><EBOV><Ebola virus><Ebola-like Viruses><Electronic Mail><Email><Ensure><Evaluation><Evaluation Research><Experimental Designs><Financial Management><Frankfurt-Marburg Syndrome Virus><Funding><Future><Gene Transcription><Genetic Transcription><Goals><Grant><Human Resources><Immune response><Immunological response><Infection><Information Dissemination><Institution><Intellectual Property><Investigation><Investigators><Knowledge><Laboratories><Lead><Leadership><Manpower><Marburg><Marburg virus><Marburg-like Viruses><Marburgvirus><Medical><Mission><Molecular><NIAID><NIH><National Institute of Allergy and Infectious Disease><National Institutes of Health><Occupational activity of managing finances><On-Line Systems><Online Systems><Pb element><Pediatric Hospitals><Policies><Preparation><Process><Productivity><Progress Reports><R-Series Research Projects><R01 Mechanism><R01 Program><RNA Expression><Reporting><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resource Allocation><Resources><Scientific Evaluation><Scientist><Security><Site><Site Visit><Strategic Planning><Structure><System><Task Forces><Texas><Transcription><United States National Institutes of Health><Universities><Vertebrate Animals><Vertebrates><Videoconferencing><Viral Diseases><Virus Diseases><Work><advisory team><biosafety level 4 facility><corona virus><developmental><dissemination of results><ebolavirus><electronic communication><experience><heavy metal Pb><heavy metal lead><host response><immune system response><immunoresponse><meetings><member><new approaches><novel approaches><novel strategies><novel strategy><online computer><operation><pathogenic virus><personnel><product development><programs><synergism><vertebrata><video conferencing><viral infection><viral pathogen><virus infection><virus pathogen><virus-induced disease><web based>