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Principal Investigator: Joanne G Patterson
Organization: OHIO STATE UNIVERSITY
Fiscal Year: 2024
Award: $248,993
Funding agency: National Cancer Institute
PROJECT SUMMARY
Polytobacco use, defined as concurrent use of more than one tobacco product including electronic nicotine
delivery systems (ENDS), is rising and high in lesbian, gay, bisexual, and transgender (LGBT) young adults (YA).
Between 22-40% of LGBT YA (vs 12-21% of non-LGBT YA) report past 30-day polytobacco use, and LGBT YA
are less likely to perceive tobacco use as harmful. Low risk perceptions may reinforce tobacco use and widen
existing disparities. The Food and Drug Administration (FDA) Center for Tobacco Products (CTP) is mandated
educate the public about tobacco product risks, yet no evidence describes how to effectively frame anti-
polytobacco risk communications. The proposed training objectives are for the applicant to develop advanced
skills in health communication science; bio-behavioral methods, including psychophysiological measurement;
and randomized controlled trials. These skills will be used to determine effective communication of polytobacco
use risks to at-risk LGBT YA. This proposal directly supports the FDA’s mandate to educate the public by
addressing the research priority area of Communications. While studies indicate that antitobacco
communications can successfully increase public knowledge about tobacco use risks, there are limitations to the
extant literature, as follows: (1) While strategies for effective risk communication are well-established, less is
known about how to frame behavioral choices (e.g., total tobacco cessation vs switching to ENDS) to increase
tobacco risk perceptions and intentions to quit in polytobacco users. (2) Antitobacco campaigns often leverage
cultural targeting, a broadly supported but costly communications strategy, to increase at-risk population
engagement. No studies have experimentally tested the effectiveness of LGBT culturally targeted vs non-
targeted anti-tobacco messages. (3) Mobile multimedia messaging has been used to disseminate smoking
cessation communications and may be feasible for distributing anti-polytobacco messages to LGBT YA, but this
has not been investigated. Using formative and summative evaluation, the applicant will address these gaps with
three Specific Aims: (1) Identify absolute and relative risk anti-polytobacco messages that effectively
communicate polytobacco risks to YA; (2) Determine the effects of cultural targeting on LGBT YA polytobacco
users’ attention to anti-polytobacco messages and perceived effectiveness; (3b) Assess the feasibility of
delivering MMS anti-polytobacco messages developed in Aims 1 and 2 to LGBT YA via texting; and (3b) Estimate
effect sizes of exposure to anti-polytobacco messages on risk perceptions and tobacco use over time. These
aims support the National Cancer Institute’s (NCI) tobacco control research priority to reduce tobacco disparities
by determining effective antitobacco message framing and cultural targeting to increase polytobacco risk
perceptions and reduce tobacco use in an at-risk population, LGBT YA. Findings will provide public health
officials, NCI, and the FDA CTP critical information about messages and digital media that may be leveraged in
national health communications to reduce poly-tobacco use in at-risk populations.
Terms: <21+ years old><Address><Adult><Adult Human><Affect><Area><Attention><Behavior><Behavioral><Communication><Data><Disparities><Disparity><Effectiveness><Electrodermal Response><Electronic Nicotine Delivery Product><Electronic Nicotine Delivery Systems><Evaluation><Exposure to><Food and Drug Administration><Future><Galvanic Skin Response><Goals><Groups at risk><Harm Minimization><Harm Reduction><Health><Knowledge><LGBT><Laboratories><Lesbian Gay Bi-sexual Transgender><Lesbian Gay Bisexual Transgender><Life><Literature><Measurement><Measures><Methods><Multimedia><Multimedium><NCI Organization><National Cancer Institute><Nicotine><Nicotine Dependence><Patient Self-Report><People at risk><Persons><Persons at risk><Phase><Physiologic Psychology><Physiological Psychology><Population><Populations at Risk><Psychogalvanic Reflex><Psychophysiological><Psychophysiology><Public Health><Randomized, Controlled Trials><Relative Risks><Reporting><Research Priority><Risk><Risk Behaviors><Risk Reduction><Risky Behavior><Science><Self-Report><Skin Electric Conductance><Smoker><Testing><Text><Text Messaging><Time><Tobacco><Tobacco Cessation><Tobacco Consumption><Tobacco Control Research><Tobacco Use Cessation><Tobacco use><Training><USFDA><United States Food and Drug Administration><adult youth><adulthood><at risk behavior><biobehavior><biobehavioral><cease smoking><cigarette smoking><cigarette use><cost><crowd source><crowd-sourcing><crowdsource><crowdsourcing><cultural values><digital><digital media><dissemination strategy><effectiveness testing><electronic nicotine delivery device><electronic nicotine distribution system><eye tracking><health communication><nicotine addiction><nicotine dependent><physiopsychology><poly use tobacco><poly-tobacco><poly-tobacco use><polytobacco><polytobacco use><prevent><preventing><psycho-physiological><quit smoking><randomized control trial><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduce tobacco use><reduces risk><reduces the risk><reducing risk><reducing the risk><reduction in tobacco use><risk perception><risk-reducing><short message service><skills><skin conductance><smoking cessation><stop smoking><texting><tobacco product use><tobacco products><tobacco use reduction><uptake><visual tracking><young adult><young adulthood>