Document text
Principal Investigator: George Parsons Langan
Organization: UNIVERSITY OF CHICAGO
Fiscal Year: 2024
Award: $1,081,907
Funding agency: National Institute of Allergy and Infectious Diseases
PROJECT ABSTRACT (Core 1/C1Facilities@HTRL)
Core 1 Facility Management, Maintenance and Operations Core (C1Facilities@HTRL) The Facility
Management, Maintenance, and Operations Core will operate the Howard T Ricketts Regional Biocontainment
Laboratory (HTRL) A/BSL3 to ensure continuous containment through decontamination, retesting, certification,
preventive maintenance, repair, or replacement of existing equipment and building systems as well as
compliance with Biosecurity, Environmental Health and Biosafety regulations. Central to this facility's past and
future success is the collective approach of HTRL management which involves four distinct entities: Animal
Resources Center, the Office of Research Safety, Facility Operations, and the Department of Microbiology.
The HTRL management team is composed of outstanding leaders in their respective fields, and they utilize
their expertise collaboratively to support the HTRL program with the common goal of assuring research
programs are safe and successful. This approach has allowed the building to operate efficiently since its initial
construction. This management structure is centered on supporting the research labs using the A/BSL3 to
allow them to focus on their experimental objective, while biosafety and operational management are
maintained by C1Facilities@HTRL. The core management team maintains the A/BSL3 rooms, equipment,
and operations at the highest level to meet or exceed the regulatory and best-practice standards for biosafety,
animal care, and research support. Furthermore, the team maintains the facility at a high level of readiness to
support ongoing and future research needs of the facility, and to adapt to the needs presented by public health
emergencies such as occurred with the establishment of the COVID-19 Core.
Terms: <2019 novel corona virus><2019 novel coronavirus><2019-nCoV><Animal Experimental Use><Animal Experimentation><Animal Research><Anthrax><Anthrax disease><Area><BSL-3 facility><BSL3 facility><Bacillus><Biomedical Research><Brucella><COVID-19><COVID-19 virus><COVID19 virus><CV-19><Certification><Chicago><CoV-2><CoV2><Collaborations><Containment><Coronavirus Infectious Disease 2019><County><Coxiella><Decontamination><Docking><ESKAPE><ESKAPE pathogens><Ensure><Environmental Health><Environmental Health Science><Equipment><Future><Goals><Grippe><Guidelines><Humidity><Illinois><Infectious Diseases / Laboratory><Infectious Diseases Research><Influenza><Institution><Laboratories><M tb><M tuberculosis><M. tb><M. tuberculosis><MRSA><Maintenance><Methicillin Resistant S. Aureus><Microbiology><Mycobacterium tuberculosis><NIH><National Institutes of Health><Operations Research><Organism><Pathogenicity><Plague><Preparedness><Preventive><Readiness><Regulation><Research><Research Support><Rickettsia><Rickettsiales><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Safety><Secure><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome related corona virus 2><Structure><System><Temperature><Testing><United States National Institutes of Health><Universities><Wuhan coronavirus><Yersinia><Yersinia pestis disease><animal care><animal experimentations><animal resource><biocontainment facility><biocontainment lab><biocontainment laboratory><biosafety level 3 facility><biosecurity><coronavirus disease 2019><coronavirus disease 2019 virus><coronavirus disease-19><coronavirus disease-19 virus><coronavirus infectious disease-19><emerging pathogen><hCoV19><improved><life span><lifespan><living system><methicillin resistance Staphylococcus aureus><methicillin resistant Staphylococcus aureus><methicillin resistant strains of Staphylococcus aureus><mtb><nCoV2><new drug treatments><new drugs><new pathogen><new pharmacological therapeutic><new therapeutics><new therapy><new vaccines><next generation therapeutics><next generation vaccines><novel drug treatments><novel drugs><novel pathogen><novel pharmaco-therapeutic><novel pharmacological therapeutic><novel therapeutics><novel therapy><novel vaccines><operation><operations><pathogenic virus><pressure><programs><public health emergency><repair><repaired><research facility><success><viral pathogen><virus pathogen>