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Principal Investigator: LAUREN BERGER SHOMAKER
Organization: COLORADO STATE UNIVERSITY
Fiscal Year: 2024
Award: $102,081
Funding agency: National Heart Lung and Blood Institute
Project Summary
Lauren Shomaker, Ph.D., is a licensed clinical psychologist and clinical researcher with a strong track record of
NIH grantsmanship, scholarship, and commitment to mentoring in patient-oriented research (POR) at the
intersection of mental health and cardiometabolic health. Dr. Shomaker's POR program is embedded in
developmental and prevention science frameworks, with a particular focus on intervening at sensitive windows
such as adolescence that are ripe with opportunity for altering lifecourse trajectories of mental/behavioral health
and cardiovascular disease (CVD) risk. In particular, her work centers on developing more targeted approaches
than “one-size-fits-all” lifestyle approaches for type 2 diabetes (T2D) and CVD prevention, through intervening
with underlying, stress-related risk factors, especially in adolescents facing heightened social adversity. Dr.
Shomaker's current, key projects as PI (R01DK132557, U/R01AT011008, R01DK111604, USDA2022-
4152037651): (1) Span the behavioral trials spectrum, (2) Are single and multisite, (3) Occur in diverse settings,
(4) Address social/psychological/behavioral underpinnings of T2D/CVD risk, and (5) Have a common thread of
applying an interdisciplinary, team science approach to mental health and T2D/CVD prevention science. Dr.
Shomaker's long-term career goals are to lead a cutting-edge POR program in mental/behavioral health and
T2D/CVD prevention that has sustained funding and effective partnerships, and to support a legacy of scientists
who will optimize feasible, acceptable, effective, and sustainable interventions for mental/behavioral health and
T2D/CVD prevention, to reduce population-level health disparities. An NHLBI K24 Midcareer Investigator Award
in POR provides the ideal mechanism to alleviate her clinical, teaching, and service responsibilities, and allow
Dr. Shomaker to augment her POR capabilities by filling two gaps, dissemination and implementation (D&I)
science and computer/information technology (CIT) tools for interventions, both of which are pivotal for
advancing the impact and reach of her work. The K24 also would provide an opportunity to obtain new, formalized
training in mentoring, with a particular emphasis on diversity, equity, and inclusion, to bolster inclusive excellence
in mentoring diverse, beginning clinical investigators. The K24 training aims, to gain formalized knowledge/skills
in (1) D&I science, (2) application of CIT tools to T2D/DVD preventative interventions, and (3) mentoring skills,
are supported by an exceptional midcareer mentorship and advisory team (D&I science: Mentor Bethany Kwan,
PhD, Co-mentors Russell Glasgow, PhD, Jesse Owen, PhD; CIT tools: Mentor Joshua Smyth, PhD; Mentorship:
Mentor Randi Streisand, PhD, Co-mentor Stanley Szefler, MD; Advisors: Matthew Hickey, PhD, Paul MacLean,
PhD). This K24 proposal leverages the institutional resources of Colorado State University, University of
Colorado Anschutz, and the CTSA-supported Colorado Clinical & Translational Sciences Institute. Specific aims
are to (1) Augment expertise in D&I science and CIT intervention supplements, and (2) Provide skillsful mentoring
to beginning clinical investigators in the conduct of POR in mental/behavioral health and T2D/CVD prevention.
Terms: <12-20 years old><21+ years old><Address><Adolescence><Adolescent><Adolescent Youth><Adult><Adult Human><Adult-Onset Diabetes Mellitus><Advisory Committees><Affect><American Psychological Association><Area><Attention><Award><Behavioral><Behavioral trial><CVD prevention><Cardiometabolic Disease><Cardiometabolic Disorder><Cardiovascular Diseases><Career Development Awards><Career Development Awards and Programs><Career Development Programs K-Series><Cause of Death><Children's Hospital><Clinical><Clinical Investigator><Clinical Trials><Collaborations><Color><Colorado><Committee Members><Communities><Computers><Development><Doctor of Philosophy><Early Intervention><Economics><Education><Educational aspects><Educational process of instructing><Effectiveness><Faculty><Family><Foundations><Funding><Goals><Grant><Health><Incidence><Information Technology><Institution><Insulin Resistance><Intervention><Intervention Strategies><Investigators><K-Awards><K-Series Research Career Programs><K24 Award><K24 Mechanism><K24 Program><Ketosis-Resistant Diabetes Mellitus><Knowledge><Lead><Leadership><Licensing><Life Cycle><Life Cycle Stages><Life Style><Lifestyle><Maturity-Onset Diabetes Mellitus><Medical><Medical center><Mental Health><Mental Hygiene><Mentors><Mentorship><Metabolic syndrome><Mid-Career Clinical Scientist Award (K24)><Midcareer Investigator Award in Patient-Oriented Research><Midcareer Investigator Award in Patient-Oriented Research (K24)><Modeling><Morbidity><Morbidity - disease rate><NHLBI><NIDDK><NIDDM><NIH><National Heart, Lung, and Blood Institute><National Institute of Diabetes and Digestive and Kidney Diseases><National Institutes of Health><Non-Insulin Dependent Diabetes><Non-Insulin-Dependent Diabetes Mellitus><Noninsulin Dependent Diabetes><Noninsulin Dependent Diabetes Mellitus><Obesity><Paper><Pb element><Pediatric Hospitals><Ph D student><Ph D. student><Ph. D. student><Ph.D student><Ph.D.><Ph.D. student><PhD><PhD student><PhD. student><Population><Preventative intervention><Prevention><Psyche structure><Psychological Health><Psychologist><Public Health><Research><Research Career Program><Research Personnel><Research Resources><Researchers><Resources><Risk Factors><Role><Scholarship><Science><Scientist><Secure><Services><Site><Slow-Onset Diabetes Mellitus><Solid><Stable Diabetes Mellitus><Stress><Students><T2 DM><T2D><T2DM><Task Forces><Teaching><Time><Training><Translational Research><Translational Science><Type 2 Diabetes Mellitus><Type 2 diabetes><Type II Diabetes Mellitus><Type II diabetes><United States National Institutes of Health><Universities><Work><adiposity><adolescence (12-20)><adolescent depression><adolescents with depression><adult onset diabetes><adulthood><advisory team><behavioral health><cardiac disease prevention><cardiometabolic><cardiometabolic risk><cardiometabolism><cardiovascular disease prevention><cardiovascular disease risk><cardiovascular disorder><cardiovascular disorder prevention><cardiovascular disorder risk><career><child depression><childhood depression><childhood onset depression><community engaged participatory research><community engaged research><community partnered research><community-engaged study><community-partnered study><corpulence><depressed adolescents><depression in adolescence><developmental><disease risk><disorder risk><disparity in health><dissemination science><diversity, equity, and inclusiveness><doctoral student><economic><equity, diversity, and inclusion><ethnic disparities in health><ethnic health disparity><experience><group of color><health disparity><heavy metal Pb><heavy metal lead><implementation science><individual of color><innovate><innovation><innovative><insulin resistant><insulin tolerance><intervention for prevention><interventional strategy><juvenile><juvenile human><ketosis resistant diabetes><lens><lenses><life course><maturity onset diabetes><mental><mortality><next generation><patient oriented research><patient oriented study><pediatric depression><people of color><person of color><population of color><pre-doc><pre-doctoral><predoctoral><prevent><preventing><prevention intervention><preventional intervention strategy><preventive intervention><programs><progression risk><psychologic><psychological><pubertal transition><puberty transition><racial disparities in health><racial health disparity><rural area><rural location><rural region><skills><social><social adversity><social role><standard of care><technology intervention><technology-based interventions><technology-enabled interventions><technology-focused interventions><tool><transition out of puberty><translation research><translational investigation><type 2 DM><type II DM><type two diabetes><urban environment><urban setting><virtual><youth depression>