EMPOIS'ON, verb transitive s as z. 1. To poison; to administer poison to; to destroy or endanger life by giving or causing to be taken into the stomach any noxious drug or preparation. [In this sense, poison is generally used; but empoison may be used, especially in poetry.] 2. To taint with poison or venom; to render noxious or deleterious by an admixture of poisonous substance. [This may be used, especially in poetry.] 3. To embitter; to deprive of sweetness; as, to empoison the joys and pleasure of life.
Source: Webster's 1828 American Dictionary ↗ · public-domain · returned verbatim, no AI