Foreword The bioeconomy represents one of the most profound opportunities of our time – a bridge between innovation and impact, science and society, economic growth and environmental stewardship. Bio-innovation’s potential to reshape industries, strengthen domestic supply chains, and create new models of national competitiveness is no longer theoretical. It is real, it is rising and it is ready to be scaled. Yet the bioeconomy stands at a crossroads. While the pace of technological advancement has been extraordinary, mainstream adoption remains limited. Too often, stakeholders lead with a technology- push approach, driven by scientific possibilities rather than market readiness. To unlock the full potential of bio-innovation, a fundamental shift is needed – one that ensures innovation is not only possible, but also commercially viable, regionally relevant and socially impactful. Amid rising geopolitical uncertainty, climate instability and economic volatility, governments and industry are under pressure to do more with less – driving inclusive growth, promoting innovation and cultivating resilience despite limited resources. In this new normal, bio-innovation must not be perceived as “nice to have”, but as a strategic imperative. A well-developed bioeconomy can be a powerful catalyst for new economic models, future-ready supply chains and national competitiveness – while advancing global sustainability. Across the globe, over 50 national strategies are focused on accelerating the bioeconomy. But strategy alone is not enough. Coordinated, actionable frameworks that deliver clear outcomes and remove barriers are needed urgently. This means policy environments that favour a market-pull dynamic – supported by compelling fiscal incentives, trustworthy regulation and tailored financial support mechanisms that enable breakthroughs to scale with speed and responsibility. Together with our global partners, the World Economic Forum’s Bioeconomy Initiative has developed this Policy Framework as a call to action. Drawing from real-world success stories, it offers actionable recommendations that guide policy-makers and industry leaders to cohesive, outcome-driven implementation. Effective policy is a powerful driver of transformation, and sharing global best practices is essential to unlocking scalable, locally adapted solutions. Taken together, the recommendations presented herein aim to help regions achieve more amid rising geopolitical uncertainty. The Forum’s Bioeconomy Initiative, in close collaboration with Capgemini and dsm-firmenich, brings together a community of government, academic and industry leaders, united by a shared ambition: to accelerate the transition toward a commercial, scaled and technology-driven bioeconomy. The bioeconomy is no longer a distant vision. But success depends on bold leadership and collaborative efforts across borders, sectors and disciplines. Now is the time to act with clarity and purpose: to design policy that moves beyond strategy documents to enable innovation, accelerate adoption and ensure the bioeconomy becomes a cornerstone of sustainable economic growth and global competitiveness. Let’s not just imagine what’s possible tomorrow. Let’s shape it together today. From Policy to Practice: Actionable Recommendations for a Commercial BioeconomyJune 2025 Roshan Gya Chief Executive Officer, Capgemini Invent Jeremy Jurgens Managing Director, Centre for the Fourth Industrial Industrial Revolution and Centre for Cybersecurity, World Economic Forum Sarah Reisinger Chief Science and Research Officer, dsm-firmenich From Policy to Practice: Actionable Recommendations for a Commercial Bioeconomy 3

From Policy to Practice Actionable Recommendations for a Commercial Bioeconomy 2025