Healthcare in a Changing Climate 2025

Contents Foreword Executive summary 1 Preparing for the climate-induced health crisis 1.1 Quantifying the impact of future climate events on public health 1.2 Implications for population health and well-being, including global economic impact 2 The potential to mitigate the health and economic impacts of climate change 2.1 Assessing the health and economic impacts of interventions 2.2 The potential to reduce climate’s impact on health by 2050 2.3 Mitigation strategies for health and economic impacts – by diseases 3 Unlocking innovation across life sciences and technology 3.1 Pivotal role of life sciences innovators in climate and health solutions 3.2 Level of investment needed and estimated returns 3.3 Overcoming roadblocks that hinder development of new climate and health solutions 3.4 Life sciences innovation for health systems resilience and equity 3.5 Avenues for further research: how climate affects non- communicable diseases Conclusion Appendix: Methodology and assumptions Overview 1 Starting point: highest burden climate-induced diseases 2 Prioritization of unmet medical needs by disease 3 Building investment cases for how to address unmet medical needs and produce step-change impact reductions Contributors Endnotes4 5 6 6 7 9 9 11 13 21 21 22 22 28 30 31 32 32 33 34 35 40 41 Healthcare in a Changing Climate: Investing in Resilient Solutions 3