01 Sugerman measles 508

CDC ACIP — Vaccine Advisory Committee

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U.S. Measles Update
April 15, 2025Centers for Disease Control and Prevention
National Center for Immunization & Respiratory Diseases
CAPT David Sugerman, MD MPH FACEP, USPHS
Senior Scientist, 2025 Measles Response
Division of Viral Diseases / National Center for Immunization and Respiratory Diseases
US Centers for Disease Control and Prevention (CDC)
History of measles cases in the U.S., 1962 –2023
†Measles was declared eliminated in the U.S. in 2000 by WHO/PAHO. Elimination is defined as the absence of endemic measles 
transmission in a region for ≥ 12 months in the presence of a well -performing surveillance system
Texas: 
2025: 541 cases*
MMR % unknown Measles outbreaks with 50+ cases and MMR vaccine coverage among affected populations – U.S. 2001 –2025
*As of April 11th, 2025
 
National and State Level 2 -dose MMR Coverage among 
Kindergartners: 2023 –2024 
https://www.cdc.gov/mmwr/volumes/73/wr/mm7341a3.htm
MMR (2 doses)
2019 -20 95.2%
2020 -21 93.9%
2021 -22 93.0%
2022 -23 93.1%
2023 -24 92.7%
County -level coverage with ≥ 1 dose of MMR vaccine 
Seeskin , ZH et al.  Estimating county -level vaccination coverage using small area estimation with the National 
Immunization Survey -Child, Vaccine, Vol 42, Issue 3,2024, Pages 418 -425.

U.S. monthly measles cases by rash onset, 2023 –2025
YearConfirmed measles 
cases
2023 59
2024 285
2025 712*
*As of April 10th, 2025.050100150200250300350400
Jan Feb Mar Apr May Jun JulAug Sep Oct Nov Dec Jan Feb Mar Apr May Jun JulAug Sep Oct Nov Dec Jan Feb Mar Apr
2023 2024 2025
U.S. measles outbreaks, 2023 –2025 
Year No. outbreaksNo. (%) cases 
associated
with outbreaks / total 
cases Outbreak size,
median cases 
(maximum)Outbreak duration,
median days 
(maximum)
2023 4 28/58 (48%) 7 (10) 22 (31)
2024 16 194/285 (68%) 4 (58) 17.5 (131)
2025 7 660/712 (93%) 5 (591)12.5 (5 outbreaks 
ongoing)
•As of April 10 , 2025, Texas, New Mexico, and Oklahoma have reported 591 confirmed cases associated with this 
single outbreak (528 in Texas ,56 in New Mexico , and 7 in Oklahoma ).
As of April 10, 712 confirmed measles cases have been 
reported by 25 states in 2025

National and Southwest Outbreak Measles Cases, 2025  
(As of April 10th, 2025)*

•Age
-Under 5 years: 225 (32%)
-5-19 years: 274 (38%)
-20+ years: 198 (28%)
-Age unknown: 15 (2%)
•Vaccination Status: 
-Unvaccinated or Unknown: 97%
-One MMR dose: 1%
-Two MMR doses: 2%
•Hospitalizations
-11% of cases (79 of 712) for management of measles 
complications
•Deaths - 2 in Texas and 1 in New Mexico  Epidemiology of U.S. measles cases in 2025 (n=712)

Distribution of Distinct Sequence Identifiers ( DSIds ) for measles 
genotypes B3 and D8 detected in the U.S. by epidemiological week 
in 2025
D8-9171
0510152025303540
1 2 3 4 5 6 7 8 9 10 11 12# Genotyped Cases
Epidemiological Week
B3-9260 B3-8777 B3-9259 B3-8841 B3-8661 D8-9171
D8-9274 D8-9304 D8-9322 D8-9323 D8-5963Green: B3
Blue:    D8
•Texas Epi -Aid: 15 deployers from CDC provided on -site technical  assistance  in Texas 
during 3/4 -4/1, with another team deploying this week.  
-Provided infection prevention control support for 7 healthcare facilities with ventilation 
assessments by NIOSH
-Review ed school infection control activities and risk mitigation strategies 
-Developed an int ernal dashboard for TX to track cases by location and exposure location
•Provide remote technical assistance to multiple state health departments
•Biweekly national measles calls with public health partners 
•Biweekly trilateral calls with Canada and Mexico to share updates and lessons learned
•Continue to make additional, outbreak -related MMR vaccine doses available for 
health departments to order at their requestCDC 2025 measles outbreak response efforts
•Provider Outreach 
-Health Alert Network (HAN) released - Expanding Measles Outbreak in Texas and New 
Mexico and Guidance for the Upcoming Travel Season
-Clinician Outreach and Communication Activity (COCA) and Epi -X alerts 
-Shared a provider letter summarizing routine and outbreak -related MMR vaccination 
recommendations  
•Laboratory Support 
-Coordination with the APHL Vaccine Preventable Disease Reference Centers (VPD -RCs) for  
genotyping and  sequencing
-Expanded and standardized testing for wastewater surveillance for measles with the 
National Wastewater Surveillance System (NWSS) and Center of Excellence in Texas.
•Ongoing modeling work to determine risk CDC 2025 measles outbreak response efforts (continued)
For more information, contact CDC/ATSDR
1-800-CDC-INFO (232 -4636)
TTY:  1 -888-232-6348    www.cdc.gov           www.atsdr.cdc.gov 
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position 
of the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry.
Thank you