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COVID- 19 Vaccination ImplementationNational Center for Immunization and Respiratory Diseases
June 25, 2025Immunization Services Division
Centers for Disease Control and Prevention
•National Immunization Survey (NIS):
-Random -digit -dial cellular telephone survey of adults age ≥18 years in the U.S. (all
50 states, 5 local jurisdictions, and territories); all responses are self reported.
-Sample size: ~15,000 adult respondents weekly, ~60,000 adult respondents monthly
-Data are weighted to represent the non- institutionalized U.S. population
•Immunization Information Systems (IISs):
-Confidential, population- based databases that record all vaccine doses administered
by participating providers in a specific geographic area
-ISD receives monthly aggregate data for COVID, influenza, and RSV, and quarterly
line-level, de -identified data for individual immunizations
•Vaccine Safety Datalink:
-Estimates of vaccination coverage are based on electronic health data from multiple integrated health systemsData sources used to estimate U.S. immunization
coverage
COVID -19 Vaccination Coverage
National Immunization Survey -Fall Respiratory Virus Module
0.020.040.060.08
0.0
9/7/2024
9/14/2024
9/21/20249/28/202410/5/2024
10/12/2024
10/19/2024
10/26/2024
11/2/202411/9/2024
11/16/2024
11/23/2024
11/30/2024
12/7/2024
12/14/2024
12/21/2024
12/28/2024
1/4/2025
1/11/20251/18/20251/25/2025
2/1/20252/8/2025
2/15/20252/22/2025
3/1/20253/8/2025
3/15/20253/22/20253/29/2025
4/5/2025
4/12/20254/19/20254/26/2025Vaccination coverage (%)
Week ending date≥1 dose (65+)
≥1 dose (18+)COVID -19 V accination Coverage (≥1 Dose) Among Adults 18 Years and Older
and 65 Years and Older , 2024- 2025
National Immunization Survey -Fall Respiratory Virus Module
44.1
23.0
0255075100
Sep 7
Sep 14
Sep 21Sep 28
Oct 5
Oct 12Oct 19Oct 26
Nov 2Nov 9
Nov 16Nov 23Nov 30
Dec 7
Dec 14Dec 21Dec 28
Jan 4
Jan 11Jan 18Jan 25
Feb 1Feb 8
Feb 15Feb 22
Mar 1Mar 8
Mar 15Mar 22Mar 29
Apr 5
Apr 12Apr 19Apr 26
Sep 7
Sep 14Sep 21Sep 28
Oct 5
Oct 12Oct 19Oct 26
Nov 2Nov 9
Nov 16Nov 23Nov 30
Dec 7
Dec 14Dec 21Dec 28
Jan 4
Jan 11Jan 18Jan 25
Feb 1Feb 8
Feb 15Feb 22
Mar 1Mar 8
Mar 15Mar 22Mar 29
Apr 5
Apr 12Apr 19Apr 26
Sep 7
Sep 14Sep 21Sep 28
Oct 5
Oct 12Oct 19Oct 26
Nov 2Nov 9
Nov 16Nov 23Nov 30
Dec 7
Dec 14Dec 21Dec 28
Jan 4
Jan 11Jan 18Jan 25
Feb 1Feb 8
Feb 15Feb 22
Mar 1Mar 8
Mar 15Mar 22Mar 29
Apr 5
Apr 12Apr 19Apr 26≥18 years 65-74 years ≥75 yearsVaccination coverage (%)
2024- 25 season week ending dateVaccination coverage (2024-25) Vaccination coverage (2023-24)COVID -19 Vaccination Coverage Among Adults ≥18 Years, 65 -74 Years,
and ≥75 Years, 2023 -24 and 2024 -25
National Immunization Survey -Fall Respiratory Virus Module
23.0
21.
642.7
37.946.5
38.3
0255075100Vaccination coverage (%)
Week ending dateOverall (6 months-17 years) 6 months-4 years 5-11 years 12-17 yearsCOVID -19 Vaccination Coverage* Among Children 6 Months –17 Years of
Age, October 2024 –April 2025, NIS -Flu
* Up -to-date with the updated 2024 –25 COVID -19 vaccine is defined as receipt of at least one vaccination since August 22, 2024, for children ≥5 years; for children <5 years, up -to-
date status was defined based on the current recommendations that also take into account number of doses and brand of vaccine. Up- to-date status was determined by survey
questions on month and year of most recent COVID- 19 vaccine, and for children <5 years, total number of COVID -19 vaccinations re ceived and brand of most recent COVID- 19
vaccine.
COVID -19 V accination Coverage (≥2 Doses) Among Adults 18 Years and Older
Who Are Immunocompromised Who Received First Dose in August/September
2024, as of End of March 2025
National Immunization Survey -Fall Respiratory Virus Module
*Immunocompromised a dults were recommended to receive a second dose of 2024 -2025 COVID- 19 vaccine
six months after their first dose .2.416.60.81.49.98.1
0.0 10.0 20.0 30.0 40.0 50.0 60.018-49 (n=85)50-64 (n=98)65+ (n=172)Male (n=95)Female (n=257)Overall 18+ immun
ocompromised
(n=355)
Weig
hted % (95% CI)
•COVID -19 vaccination coverage for older adults improved in 2024-2025
compared to the previous season, but vaccination coverage for all adults >
18 years was similar between the 2023-2024 and 2024-2025 seasons.
•Approximately 13% of children between 6 months and 17 years of age
were up to date with COVID vaccination at the end of April 2025. Summary
For more information, contact CDC/ATSDR
1-800- CDC- INFO (232- 4636)
TTY: 1 -888- 232- 6348 www.cdc.gov www.atsdr.cdc.gov
The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry.
Thank you