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Principal Investigator: Benjamin P. Linas
Organization: WEILL MEDICAL COLL OF CORNELL UNIV
Fiscal Year: 2024
Award: $1,599,903
Funding agency: National Institute on Drug Abuse
The HEAL Data2Action (D2A) Program is a coordinated effort to promote the synthesis and real-world
application of existing data to guide and monitor improvements in service delivery to prevent or treat opioid use
disorder (OUD) and pain. Collectively, these projects will address gaps in the delivery of evidence-based
practices in each of the four pillars of the HHS Overdose Prevention Strategy: primary prevention, harm
reduction, treatment of opioid use disorder, and recovery support. The HEAL D2A Modeling and Economic
Resource Center (MERC) will support the HEAL D2A Innovation Projects by providing expertise in simulation
modeling and economic evaluation methods and will consult with the HEAL D2A Innovation Grant recipients on
applying these methods and insights in their local implementation activities. The MERC will also conduct
original research applying state-of-the-art economic and simulation modeling expertise to understand and
address the overdose crisis. Since 2015, we have worked collaboratively to lead a highly successful multi-
institutional NIDA-funded national center of excellence, the Center for Health Economics of Treatment
Interventions for Substance Use Disorder, HCV, and HIV (CHERISH). We are thus uniquely qualified to lead
the HEAL D2A MERC with the following aims: 1) to support the HEAL D2A Innovation Projects by providing
methodological consultation on the application of rigorous modeling techniques, cost analyses, and behavioral
economic strategies to support the projects' selection and implementation of evidence-based practices to
address service delivery needs; 2) to develop tools that can be readily used by the Innovation Projects to make
informed decisions about the relative costs of different implementation interventions to different stakeholders,
to measure the overall costs of these efforts, and to inform the design of appropriate payment systems that
support sustainability; 3) to use meta-modeling techniques to develop a user-friendly interface so that
simulation model results generated for one system or community can be adapted for other
systems/communities or adapted when local circumstances change; 4) to conduct novel research using
advanced modeling and health economics approaches that build on existing data to provide insights into the
complex dynamics of addressing the overdose crisis through strategic implementation of evidence-based
practices. The HEAL D2A MERC will support the application of health economics and modeling research to
real-world decision making about services to prevent or treat opioid use disorder and pain, will further scientific
innovation in the field, and will establish a paradigm for integrating health economics and modeling into
substance use treatment and prevention policies at the system level. The HEAL D2A MERC will be
collaborative with the work of the HEAL D2A Research Adoption Support Center (RASC), including the
consultations and catalog of measures and tools of the Implementation Support Cores, and will leverage and
contribute to the resources of the HEAL D2A Data Infrastructure Support Center (DISC).
Terms: <AIDS Virus><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome Virus><Address><Adoption><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Caring><Catalogs><Communities><Complex><Consult><Consultations><Cost Analyses><Cost Analysis><Costs and Benefits><Coupled><Data><Decision Making><Economics><Educational workshop><Epidemiology><Evidence based practice><Funding><Grant><HCV><HCV/HIV><HEAL Initiative><HIV><HIV and HCV><HIV and hepatitis C><HIV-HCV><HIV/HCV><HIV/Hepatitis C><Harm Minimization><Harm Reduction><Health><Health Care Utilization><Health Services Evaluation><Health Services Research><Health behavior><Health system><Healthcare Delivery><Helping End Addiction Long-term><Helping End Addiction Longterm><Helping to End Addiction Long-term><Helping to End Addiction Longterm><Hepatitis C virus><Human Immunodeficiency Viruses><Institution><Intervention><Intervention Strategies><Investigation><Investigators><Knowledge><LAV-HTLV-III><Lymphadenopathy-Associated Virus><Measurement><Measures><Medical Care Research><Methodology><Methods><Mission><Modeling><Monitor><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Natural History><Outcome><Overdose><Pain><Painful><Persons><Policies><Preventative strategy><Prevention><Prevention strategy><Preventive strategy><Primary Prevention><Province><Qualifying><Recovery Support><Research><Research Personnel><Research Resources><Researchers><Resources><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Support System><Substance Use Disorder><Support System><System><Techniques><Virus-HIV><Visualization><Work><Workshop><assess cost><behavioral economics><catalog><chronic pain><consultation><consults><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost assessment><cost evaluation><cost outcomes><data infrastructure><data resource><data sharing><design><designing><disease model><disease risk><disorder model><disorder risk><economic><economic analysis><economic assessment><economic evaluation><epidemiologic><epidemiological><evaluate cost><examine cost><experience><health and care delivery><health application><health care delivery><health care service use><health care service utilization><health delivery systems><health economics><health related behavior><health services delivery><healthcare service use><healthcare service utilization><healthcare utilization><implementation intervention><implementation tool><improved><innovate><innovation><innovative><insight><interventional strategy><model-based simulation><models and simulation><novel><opiate use disorder><opioid use disorder><overdose prevention><payment><prevent><preventing><programs><real world application><relative cost><relative costs><service delivery><services research><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><substance use><substance use and disorder><substance use treatment><substance using><support tools><tool><user-friendly>