Document text
Principal Investigator: Jeannette Michele Beasley
Organization: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Fiscal Year: 2024
Award: $676,710
Funding agency: National Institute of Diabetes and Digestive and Kidney Diseases
PROJECT ABSTRACT
Over 24 million Americans are ≥65 years and have prediabetes. Prediabetes can be addressed using a
public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were
ages 60 and over, the diet and physical activity intervention conferred a 71% risk reduction of diabetes after an
average follow-up of 3 years. The population of older adults is projected to more than double from 52.5 million
in 2019 to ~100 million by 2060, and if projections hold, about half (48.3%) will have prediabetes. The
proposed study will compare a DPP program Tailored for Older Adults and delivered via Telehealth (DPP-TOAT
arm) to an in person DPP tailored for older adults (DPP arm) using a randomized, controlled trial design
(n=230). Our preliminary data suggests DPP-TOAT is a feasible and acceptable way to deliver the DPP to
older adults, and this will be the first study to compare the effectiveness and implementation of two strategies
(telehealth versus in-person) to deliver a tailored DPP for the unique needs of the growing population of older
adults. Eligible patients will be recruited through electronic health records (Epic and MyChart) and randomized
to the 12-month DPP-TOAT or the in-person DPP program. The primary effectiveness outcome will be 6-month
weight loss and implementation outcome will be attendance. We will use a pragmatic approach in order to
inform future studies conducted in community-based and rural settings. Findings will inform best practices in
the delivery of an evidence-based intervention that could reach the 24+ million adults aged 65 and over with
prediabetes.
Terms: <21+ years old><65 and older><65 or older><65 years of age and older><65 years of age or more><65 years of age or older><65+ years><65+ years old><> 65 years><Active Follow-up><Address><Adherence><Adopted><Adult><Adult Human><Age><Aged 65 and Over><American><Assess implementation><Body Weight decreased><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 years><Clinic><Clinical><Communities><Consolidated Framework for Implementation Research><Consolidated Framework for Implementation Science><Consolidated Framework for Implementing Change><Cost Analyses><Cost Analysis><Data><Dentition><Diabetes Mellitus><Diabetes prevention><Diagnosis><Diet><Diminished Vision><Effectiveness><Elderly><Electronic Health Record><Eligibility><Eligibility Determination><Evidence based intervention><Faculty><Federally Qualified Health Center><Future><Geriatrics><Glycohemoglobin A><Glycosylated hemoglobin A><Goals><Group Practice><Hb A1><Hb A1a+b><Hb A1c><HbA1><HbA1c><Health><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Healthcare><Healthy diet><Hearing Loss><Hemoglobin A(1)><Hospital Admission><Hospitalization><Hospitals><Hypoacuses><Hypoacusis><Implementation assessment><Incidence><Individual><Institution><Intervention><Intervention Strategies><Interview><Length of Stay><Life Style><Lifestyle><Low Vision><Measures><Medicare><Methodology><Monitor><Number of Days in Hospital><Older Population><Outcome><Outcome Assessment><Partial Sight><Participant><Patients><Persons><Physical activity><Policies><Population><Prediabetes><Prediabetes syndrome><Prediabetic State><Preventative strategy><Prevention strategy><Preventive strategy><Private Practice><Process><Protocol Screening><Public Health><Qualifying><RE-AIM><Randomized><Randomized, Controlled Trials><Reach, Effectiveness, Adoption, Implementation, and Maintenance><Reduced Vision><Research><Risk><Risk Reduction><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><Self Efficacy><Seminal><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Social Support System><Social support><Subnormal Vision><Support System><Technology><Time><Title 18><Travel><Visit><Visual impairment><Weight><Weight Loss><Weight Reduction><Weights and Measures><Work><above age 65><acceptability and feasibility><active followup><adulthood><advanced age><after age 65><age 65 and greater><age 65 and older><age 65 or older><age > 65><age of 65 years onward><aged 65 and greater><aged 65+><aged ≥65><ages><arm><assess cost><assess effectiveness><balanced diet><barriers to implementation><behavior change><body weight loss><care as usual><compare effectiveness><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><cost><cost assessment><cost evaluation><design><designing><determine effectiveness><diabetes><diabetes prevention program><diets><digital><dysfunctional hearing><effectiveness assessment><effectiveness evaluation><effectiveness outcome><effectiveness testing><effectiveness-related outcomes><effectiveness/implementation hybrid study><effectiveness/implementation study><electronic health care record><electronic health medical record><electronic health plan record><electronic health registry><electronic medical health record><evaluate cost><evaluate effectiveness><evaluate implementation><evaluation of implementation><evidence base><examine cost><examine effectiveness><exercise intervention><exercise program><experience><fitness program><follow up><follow-up><followed up><followup><geriatric><geriatric medicine><good diet><health care><health care settings><health insurance for disabled><healthcare settings><healthy life-style><healthy lifestyle><healthy weight><hearing challenged><hearing defect><hearing deficient><hearing deficit><hearing difficulty><hearing dysfunction><hearing impairment><hemoglobin A1c><hospital days><hospital length of stay><hospital stay><human old age (65+)><implementation barriers><implementation challenges><implementation cost><implementation evaluation><implementation framework><implementation investment><implementation outcomes><implementation research framework><implementation science framework><implementation study><informant><intervention program><interventional strategy><life style intervention><lifestyle intervention><old age><older adult><older adulthood><older groups><older individuals><older person><over 65 years><physical activity intervention><pre-diabetes><pre-diabetic><prediabetic><prevent><preventing><primary outcome><programs><randomisation><randomization><randomized control trial><randomly assigned><reach, efficacy, adoption, implementation, and maintenance><recruit><reduce risk><reduce risks><reduce that risk><reduce the risk><reduce these risks><reduces risk><reduces the risk><reducing risk><reducing the risk><risk-reducing><rural locality><rural place><rural setting><secondary outcome><senior citizen><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><social support network><systemic barrier><systemic hurdle><systemic obstacle><telehealth><theories><tool><treatment as usual><trial design><usual care><vision impairment><visually impaired><weights><wt-loss><≥65 years>