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Principal Investigator: Jill E Johnston
Organization: UNIVERSITY OF SOUTHERN CALIFORNIA
Fiscal Year: 2024
Award: $824,976
Funding agency: National Institute of Environmental Health Sciences
OVERALL: PROJECT SUMMARY/ABSTRACT
Near-roadway and regional air pollution, industrial releases, goods movement and growing oil and gas
production in urban areas vulnerable to wildfires all threaten to increase the burden of environmental disease. In
California and worldwide, these threats disproportionately affect children, especially in marginalized communities
and communities of color. Air pollution has adverse effects on childhood respiratory health, obesity and metabolic
outcomes, and neurodevelopment. New children’s environmental health science (CEHS) translation is needed
to develop and implement effective, science-based interventions to address these unfavorable trends. The
mission of the Southern California Center for Children’s Environmental Health Translational Research (SC-
CCEHTR) is to leverage scientific knowledge to reduce the burden of environmentally related diseases by
developing: (1) multidisciplinary CEHS translational teams building an innovative framework for multidirectional,
action-oriented engagement with communities, academia and policymakers, and (2) model collaborations
supporting junior investigators and communities to use emerging CEHS, leading to better decision-making.
Accordingly, the theme of the SC-CCEHTR is Urbanism, Air Pollution, Children’s Health and Environmental
Justice. The SC-CCEHTR will build on a foundation of a large CEHS grant base across three NIEHS Centers
and of innovative multidirectional engagement with communities and decision-makers. The proposed SC-
CCEHTR framework includes novel approaches to youth engagement and community science, urban design
and policy solutions, and communication and public knowledge. Investigators new to CEHS from communication,
policy and urban design, sociology, dramatic arts, education, network analysis and implementation science will
bring fresh approaches to this framework, focused on identifying solutions to urban air pollution by “re-imagining”
the design of the city to reduce air pollution exposure and improve children’s health. A Translation Core will bring
the SC-CCEHTR tools to bear on the development of pilot projects to better translate CEHS into community
knowledge and action. A Developmental Core responds to career development needs of junior investigators and
to emerging CEHS challenges. Innovative translational and career development collaborations will be promoted
with the Moving Forward Network of environmental justice communities, the International Society for Children’s
Health and the Environment, other Children's Environmental Health Research Translation Centers and NIEHS
P30 Core Centers, and policymakers across the country.
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