Study of Pregnancy And Neonatal Health (SPAN)

NIH Pandemic-Era Grants

Pandemic Era Grants

2024

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Principal Investigator: Edwina  Yeung
Organization: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
Fiscal Year: 2024
Award: $1,238,838
Funding agency: Eunice Kennedy Shriver National Institute of Child Health and Human Development

Recruitment is ongoing at eight clinical sites located in Alabama, Louisiana, North Carolina, Pennsylvania Utah, and Virginia. We anticipate about 11,525 pregnant women with about 3,825 of their male partners to be recruited. Pregnant women are recruited in the first half of pregnancy and followed throughout pregnancy. A research ultrasound is performed to monitor fetal growth. Delivery samples are collected and a neonatal assessment is completed. Male partners complete a study visit during pregnancy for markers of heart health and a subset provide semen samples and a body composition scan to further link heart health to neonatal health through semen epigenetics. Women with uncontrolled gestational diabetes are randomized to the timing of initiation of delivery to assess the optimal window for neonatal health.

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