Development of an Optimized Adjuvanted TB Vaccine

NIH Pandemic-Era Grants

Pandemic Era Grants

2024

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Principal Investigator: JAY  EVANS
Organization: UNIVERSITY OF MONTANA
Fiscal Year: 2024
Award: $253,399
Funding agency: National Institute of Allergy and Infectious Diseases

Vaccine Adjuvant Discovery Program: To develop a lead, optimized adjuvanted tuberculosis (TB) vaccine for IM or IN administration using specified adjuvants in combination with recombinant or circRNA TB antigens within the context
of a vaccine to prevent TB.

Terms: <Adjuvant><Antigens><Development><Lead><M tuberculosis infection><M. tb infection><M. tuberculosis infection><M.tb infection><M.tuberculosis infection><MTB infection><MTB vaccine><Messenger RNA><Mice><Mice Mammals><Modeling><Murine><Mus><Mycobacterium tuberculosis (MTB) infection><Mycobacterium tuberculosis infection><Pb element><Recombinant Proteins><Recombinants><Specific qualifier value><Specified><TB infection><TB vaccine><Tuberculosis><Tuberculosis Vaccines><Vaccine Adjuvant><Vaccine for TB><Vaccine for Tuberculosis><Vaccines><anti-TB vaccine><developmental><disseminated TB><disseminated tuberculosis><efficacy testing><heavy metal Pb><heavy metal lead><immunogen><infection due to Mycobacterium tuberculosis><mRNA><prevent><preventing><programs><tuberculosis infection><tuberculous spondyloarthropathy><vaccine against M. tuberculosis><vaccine against Mtb><vaccine against Mycobacterium tuberculosis><vaccine against TB><vaccine against tuberculosis><vaccine candidates against tuberculosis>