Document text
Principal Investigator: Yijie Wang
Organization: MICHIGAN STATE UNIVERSITY
Fiscal Year: 2024
Award: $417,388
Funding agency: National Institute on Minority Health and Health Disparities
Modified Abstract Section
Perceived negative treatment based on one’s social characteristics is a key factor contributing to mental and physical health disparities. Yet, the impact of perceived negative treatment on behavioral health outcomes such as substance use (SU) is less clear, particularly in early life (e.g. late childhood and early adolescence). By middle adolescence, SU initiation is set in motion triggering subsequent developmental trajectories. Investigating the onset of SU, starting in late childhood, is critical for mitigating its downstream health consequences. There is even less science focused on multilevel factors that alleviate associations between perceived negative treatment and SU. This project addresses these gaps in developmental and health disparities science by investigating multiple forms of perceived negative treatment and SU (self-report & hair sample metabolites) from late childhood to middle adolescence, and by investigating sleep (parent-report & actigraphy duration & quality) and neighborhood environment (deprivation, crime, noise, walkability from geocodes) as moderators of the health impact of perceived negative treatment. Both sleep and neighborhood environment can be targeted by evidence-based programming as levers of change to reduce the impact of perceived negative treatment on SU. The project draws from the on-going, national, longitudinal study of Adolescent Brain Cognitive Development (ABCD), the largest national study of its kind that follows 11,875 children (9-10 years old) through adolescence. The project examines three research aims. First, the study investigates concurrent and longitudinal linkages between perceived negative treatment and SU, from late childhood to early adolescence, disentangling whether perceived negative treatment is a contributing or a resulting factor of SU initiation and continuation. Second, the study investigates the extent to which the linkages between perceived negative treatment and SU are conditioned by young people’s sleep. Finally, the study investigates the moderating role of neighborhood environment in linking perceived negative treatment, sleep, and SU, from late childhood to middle adolescence. For all research aims, the proposed project also explores how the associations of perceived negative treatment, SU, sleep, and neighborhood environment change from late childhood to adolescence, by testing multiple development-related differences (i.e., by data collection wave, developmental stage, age, grade level). Findings will elucidate critical developmental periods when interventions are most effective in helping young people facing disparities due to their various social characteristics navigate the negative health consequences of adverse social experiences. Essentially, this project will provide critical insights for youth SU programs including who is most at risk, what to target, and when to intervene.
Terms: <0-11 years old><10 year old><10 years of age><12-20 years old><21+ years old><Active Follow-up><Address><Adolescence><Adolescent><Adolescent Youth><Adopted><Adult><Adult Human><Age><Brain><Brain Nervous System><Buffers><Categories><Child><Child Youth><Childhood><Children (0-21)><Cognitive Discrimination><Country><Crime><Data><Data Collection><Decrease health disparities><Development><Disadvantaged minority><Discrimination><Emotional><Encephalon><Environment><Environmental Factor><Environmental Risk Factor><Equity><Ethnic Origin><Ethnicity><Exclusion><Goals><Hair><Health><Health Disparities Research><Health Inequity><Health behavior><Health disparities related research><Health disparity mitigation><Health disparity reduction><Immigration><Individual><Individuals from minority><Individuals of minority><Inequalities in Health><Inequities in Health><Intervention><Intervention Strategies><Life><Link><Longitudinal Studies><Lower health disparities><Measures><Mental Health><Mental Hygiene><Methodology><Minority Groups><Minority People><Minority Population><Minority individual><Mitigate health disparities><Modeling><Motion><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Neighborhoods><Noise><Outcome><Parents><Patient Self-Report><Persons><Physiologic><Physiological><Population><Prejudice><Psychological Health><Public Health><Race><Races><Reduce health disparities><Reporting><Research><Risk><Risk Factors><Role><Sampling><Science><Self-Report><Sex Orientation><Sexual Orientation><Shapes><Sleep><Sleep disturbances><Stress and Coping><Testing><Time><Weight><Work><Youth><Youth 10-21><aberrant sleep><actigraph><actigraphy><active followup><adolescence (12-20)><adolescent substance use><adulthood><age 10 years><ages><base><bases><behavioral health><biobehavior><biobehavioral><cognitive ability><cognitive development><coping with stress><critical developmental period><deprivation><developmental><disparity in health><disrupted sleep><disturbed sleep><early adolescence><environmental risk><evidence base><experience><experienced discrimination><follow up><follow-up><followed up><followup><health disparities science><health disparity><health inequalities><health related behavior><impaired sleep><indexing><innovate><innovation><innovative><insight><interventional strategy><irregular sleep><juvenile><juvenile human><kids><long-term study><longitudinal outcome studies><longterm study><marginalized group><marginalized individual><marginalized people><marginalized population><minority health><minority health disparity><novel><parent><pediatric><perceived discrimination><perception of discrimination><physical conditioning><physical health><programs><prospective><psychosocial><racial><racial background><racial origin><self-reported discrimination><sleep disruption><sleep dysregulation><sleep health><sleep hygiene><social><social factors><social role><stress-related coping><substance use><substance use among adolescents><substance use among youth><substance using><ten year old><ten years of age><weights><youngster><youth substance use>