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Principal Investigator: Lynn T Singer
Organization: CASE WESTERN RESERVE UNIVERSITY
Fiscal Year: 2020
Award: $161,000
Funding agency: National Institute on Drug Abuse
PROJECT SUMMARY
The Planning for the HEALthy Early Development Study will contribute to the design and recommended
protocol for a future large-scale, multi-site research study to prospectively examine human brain, cognitive,
behavioral, social and emotional development of children beginning prenatally through ages 9-10, and to
determine the impact of maternal pre- and postnatal substance use on short- and long-term development of
children. The Planning Study will link investigators across 6 research sites who have complementary
experience and expertise in the areas that are essential to designing the study. Planning activities will be
accomplished using a coordinated set of 10 Working Groups who will work collaboratively to design a sampling
and recruitment strategy for a future large-scale study, to identify and recommend strategies for addressing the
challenges to ethical recruitment and retention of vulnerable populations, and to develop and test a common
protocol for neuroimaging, infant and child assessments, exposure assessment, biospecimen collection, and
integration of novel technologies. By the end of the Planning Phase, the 6 Consortium sites will have produced
and tested a recommended protocol for the future multi-site study, and will have established feasibility of
carrying out the study protocol at each of the 6 linked sites.
Terms: <0-11 years old><2019 novel coronavirus><2019-nCoV><AOD use><Address><Affect><Age><Alcohol Chemical Class><Alcohol or Other Drugs use><Alcohols><Antidepressant Agent><Antidepressant Drugs><Antidepressants><Antidepressive Agents><Area><Behavior><Behavioral><Benzodiazepine Compounds><Benzodiazepines><Brain><Brain Nervous System><COVID-19><COVID19><Child><Child Development><Child Youth><Children (0-21)><Cognitive><Collection><Communicable Diseases><Communities><Coping Behavior><County><Crystal Meth><Data><Deoxyephedrine><Desoxyephedrine><Development><Diagnosis><Disease><Disorder><Drugs><Economics><Emotional><Employment><Encephalon><Enrollment><Ethics><Family><Frequencies><Future><Generalized Growth><Gestation><Government><Grant><Growth><Health><History><Human><Individual><Infant><Infant and Child Development><Infectious Disease Pathway><Infectious Diseases><Infectious Disorder><Interview><Investigators><Knowledge><Link><Longitudinal Studies><Marijuana><Measures><Medication><Mental Health><Mental Hygiene><Methamphetamine><Methylamphetamine><Modern Man><N-Methylamphetamine><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Ohio><Opiate user><Opiates><Opioid><Opioid drug user><Outcome><PWUO><Participant><Pharmaceutic Preparations><Pharmaceutical Preparations><Phase><Population><Pregnancy><Pregnant Women><Protocol><Protocols documentation><Psychological Factors><Psychological Health><Quarantine><Race><Racial Group><Racial Stocks><Recording of previous events><Reporting><Research><Research Personnel><Research Proposals><Researchers><Risk><SARS-CoV-2><SARS-CoV2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related coronavirus 2><Sampling><Schools><Severe acute respiratory syndrome coronavirus 2><Severities><Site><Smoking><Social Distance><Social isolation><Social support><Socio-economic status><Socioeconomic Status><Standardization><Substance Use Disorder><Symptoms><Target Populations><Testing><Tissue Growth><Tobacco><United States><Virus><Vulnerable Populations><Woman><Work><Wuhan coronavirus><ages><anti-depressant agent><anti-depressant drugs><anti-depressants><anti-depressive agents><children><childrens'><comparator group><comparison group><coping><coping mechanism><corona virus disease 2019><coronavirus disease 2019><design><designing><developmental><drug/agent><enroll><ethical><expectant mother><expecting mother><experience><exposed in utero><fetal exposure><food insecurity><improved><in utero exposure><intra-uterine environmental exposure><intrauterine environmental exposure><isolation/quarantine><long-term study><longitudinal outcome studies><longterm study><marihuana><neuro-imaging><neuroimaging><new technology><novel technologies><offspring><ontogeny><opioid user><pandemic><pandemic disease><parent grant><patients who use opioids><people who use opioids><persons who use opioids><postnatal><pregnant><pregnant mothers><prenatal><prenatal exposure><prenatally exposed><prospective><psychological distress><recruit><research study><response><social><social support network><socio-economic position><socioeconomic position><stressor><substance use><substance using><unborn><using substances><vaping><vulnerable group><work group><working group><youngster>