Document text
Principal Investigator: Jeffrey Hsu-Min Chuang
Organization: JACKSON LABORATORY
Fiscal Year: 2024
Award: $103,689
Funding agency: National Cancer Institute
PROJECT SUMMARY / ABSTRACT
The long-term goal of the proposed program is to establish a summer undergraduate research fellowship in the
molecular biology and genomics of human cancer at The Jackson Laboratory for Genomic Medicine (JAX-GM)
in Farmington, CT that will support the need for enhanced education in cancer research and genomics for the
future biomedical workforce. This proposed program will function as a defined cohort within the existing JAX
Summer Student Program (SSP). The Jackson Laboratory is a NCI-designated Cancer Center, and JAX-GM
provides a collaborative, highly innovative research environment of scientists with diverse cancer expertise that
will support the following aims of this program: (1) Provide an authentic and mentored research experience.
JAX-GM will recruit ten students to join a cutting-edge, collaborative research team using molecular and
computational methods to investigate the etiology and evolution of human breast, ovarian, bone, and brain
cancers, leukemia, cancer immunotherapy, and genome structural variation and instability. (2) Promote
diversity in science. The participants will be chosen through a competitive, nationwide application process, and
members of underrepresented groups will be actively recruited through targeted national outreach. Each intern
will receive a full fellowship including subsistence, round-trip transportation, research supplies, and funds to
offset the cost of housing. These funds will enable economically disadvantaged students to forgo summer jobs
and participate in this life-changing educational experience. (3) Encourage careers in science and lifelong
scientific literacy. Each participant will join a sponsoring scientist's team and will design and conduct an
independent, hypothesis-driven project using advanced analytic methods and tools and the outstanding scientific
resources available at JAX-GM. The cancer research fellowship program will require students to attend
workshops on the ethical, legal, and social issues facing scientists today and complete pre-fellowship online
prequels on cancer genomics. (4) Incorporate evaluation to strengthen the program. JAX Genomic
Education staff will collect formative and summative evaluation data that will directly inform program leadership
to guide future administration of the program. The JAX institutional commitment ensures student access to
intellectual and research resources including on-campus courses and conferences, state-of-the-art
instrumentation and computational resources, dedicated program direction by JAX Genomic Education staff,
housing in a college setting, and a professionally staffed residential program. The SSP––supported by
institutional funds, private foundations, and federal grants––has well-established administrative procedures for
recruitment and selection, mentor training, guidance, program design, management, and evaluation. JAX-GM
offers a stimulating environment in which motivated, talented students from diverse backgrounds can learn the
fundamentals of scientific inquiry, contribute to real research progress, and make great strides in intellectual and
personal growth that will guide them in career choices and lifelong learning.
Terms: <Area><Award><Bio-Informatics><Bioethics><Bioinformatics><Biomedical Ethics><Biomedical Research><Bone Cancer><Brain Cancer><Breast Cancer><Business-Friendly Atmosphere><Cancer Biology><Cancer Center><Cancer Research Programs><Cancer Research Project><Cancers><Career Choice><Career Path><Causality><Climacteric><Communication><Communities><Computational toolkit><Computing Methodologies><DNA Molecular Biology><Data><Data Bases><Databases><Dedications><Development><ELSI><Economically Deprived><Education><Educational aspects><Educational workshop><Ensure><Environment><Ethics><Etiology><Evaluation><Evolution><Faculty><Feedback><Fellowship><Fellowship Program><Foundations><Funding><Future><Generalized Growth><Genome><Genomic medicine><Genomics><Glial Cell Tumors><Glial Neoplasm><Glial Tumor><Glioblastoma><Glioma><Goals><Grade IV Astrocytic Neoplasm><Grade IV Astrocytic Tumor><Grade IV Astrocytoma><Grant><Growth><Home><Housing><Human><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><Individual><Institution><Internships><Investigators><Jobs><Laboratories><Leadership><Learning><Love><Malignant Bone Neoplasm><Malignant Breast Neoplasm><Malignant Neoplasms><Malignant Osseous Neoplasm><Malignant Osseous Tumor><Malignant Ovarian Neoplasm><Malignant Ovarian Tumor><Malignant Tumor><Malignant Tumor of the Bone><Malignant Tumor of the Brain><Malignant Tumor of the Ovary><Malignant neoplasm of brain><Malignant neoplasm of ovary><Medical><Mentors><Mission><Modern Man><Molecular><Molecular Biology><NCI-Designated Cancer Center><NIH><National Institutes of Health><Neuroglial Neoplasm><Neuroglial Tumor><Occupations><Osseous Cancer><Ovary Cancer><Participant><Personal Growth><Plants><Privatization><Procedures><Process><Professional Positions><Public Health><Publications><R-Series Research Projects><R01 Mechanism><R01 Program><Recruitment Activity><Research><Research Grants><Research Personnel><Research Project Grants><Research Projects><Research Resources><Researchers><Resources><Science><Scientific Inquiry><Scientific Publication><Scientist><Societies><Solid><Student Selections><Student recruitment><Students><Talents><The Jackson Laboratory><Tissue Growth><Training><Transportation><Travel><Underrepresented Groups><Underrepresented Populations><Underrepresented Students><United States National Institutes of Health><Variant><Variation><Workshop><active recruitment><advanced analytics><analytical method><analytical tool><anti-cancer immunotherapy><anti-cancer research><anticancer immunotherapy><biomedical scientist><business-friendly environment><cancer genomics><cancer immunotherapy><cancer research><career><career aspiration><career fair><career interest><career networking><career pathway><career track><causation><cohort><collaborative atmosphere><collaborative environment><college><collegiate><computational methodology><computational methods><computational resources><computational toolbox><computational tools><computational toolset><computer based method><computer methods><computerized tools><computing method><computing resources><conference><convention><cost><data base><design><designing><developmental><disadvantaged student><disease causation><economic disparity><economically disadvantaged><education research><ethical><ethical legal and social><ethical, legal, and social implication><experience><faculty mentor><formal learning><glial-derived tumor><glioblastoma multiforme><homes><human disease><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based cancer therapies><immune-based therapies><immune-based treatments><immuno therapy><immunotherapy for cancer><immunotherapy of cancer><individualized cancer therapy><informal education><informal instruction><informal learning><innovate><innovation><innovative><instrumentation><interactive atmosphere><interactive environment><interdisciplinary atmosphere><interdisciplinary environment><interest><intern><leukemia><life change><life-long learning><lifelong learning><malignancy><malignant breast tumor><meeting><meetings><member><neoplasm/cancer><neuroglia neoplasm><neuroglia tumor><novel><oncogenomics><ontogeny><outreach><ovarian cancer><peer><peer-group atmosphere><peer-group environment><personalized cancer therapy><personalized cancer treatment><professional networking><programs><recruit><role model><scientific literacy><scientifically literate><speed networking><spongioblastoma multiforme><students who are disadvantaged><summer research><summer student><summit><symposia><symposium><under representation of groups><under represented groups><under represented people><under represented populations><undergrad><undergraduate><undergraduate education><undergraduate research><undergraduate student><underrepresentation of groups><underrepresented people>