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Principal Investigator: Noe Cuauhtemoc Crespo
Organization: SAN DIEGO STATE UNIVERSITY
Fiscal Year: 2024
Award: $609,078
Funding agency: National Institute on Minority Health and Health Disparities
Project Summary/Abstract
The United States currently has the highest COVID-19 infection and related mortality rates in the world. In
California, Latinos account for the highest percent of COVID-19 cases (58.9%) and deaths (47.3%) and are
disproportionately represented in occupations deemed as ‘essential’. Latinos also suffer from higher rates of
poverty and chronic disease which places them at greater risk of COVID-19 infection and related complications.
In collaboration with Family Health Centers of SD (FHCSD) and working with Community Health Workers (aka,
promotores/as), we will implement a multilevel intervention to increase COVID-19 vaccine completion rates and
see faster vaccination uptake among Latinos. A total of 10 clinics will be randomized to either a Standard Clinical
Practice consisting of standard clinic-based strategies to promote COVID-19 vaccine uptake among patients or
a Multilevel Intervention consisting of an individualized/tailored intervention delivered by Health Educators
working within the clinics plus a multi-component community intervention delivered by community promotores.
This project will test the immediate and short-term effectiveness of the multilevel intervention to increase COVID-
19 vaccine uptake. In addition, we will test the effectiveness of the proposed intervention on long-term behavioral,
mental, and physical health outcomes. Lastly, this project will assess implementation outcomes including
program acceptability and feasibility by patients and clinic staff and community environment. This study aims to
increase the uptake of completing the COVID-19 vaccine in a population that has exceptionally high rates of
morbidity and mortality due to COVID-19. We will harness our research team’s extensive experience in
developing multi-level interventions working with Health Educators and promotores to promote behavior change
among Latinos, and leverage a strong community-academic collaboration that maximizes community impact and
sustainability. This research will lead to the development of sustainable and scalable community-academic
models designed to respond quickly, efficiently, and effectively to both this existing and future public health
threats.
Terms: <2019-nCoV vaccine><Address><Affect><Assess implementation><Behavior Conditioning Therapy><Behavior Modification><Behavior Therapy><Behavior Treatment><Behavioral><Behavioral Conditioning Therapy><Behavioral Modification><Behavioral Therapy><Behavioral Treatment><COVID infected patient><COVID monitoring><COVID patient><COVID positive patient><COVID-19><COVID-19 associated death><COVID-19 associated fatality><COVID-19 associated mortality><COVID-19 death><COVID-19 fatality><COVID-19 induced death><COVID-19 induced fatality><COVID-19 induced mortality><COVID-19 infected patient><COVID-19 infection><COVID-19 monitoring><COVID-19 mortality><COVID-19 patient><COVID-19 positive patient><COVID-19 related death><COVID-19 related fatality><COVID-19 related mortality><COVID-19 related risk><COVID-19 risk><COVID-19 risk factor><COVID-19 vaccination><COVID-19 vaccine><COVID-19 virus infection><COVID19 associated death><COVID19 associated fatality><COVID19 associated mortality><COVID19 death><COVID19 fatality><COVID19 induced death><COVID19 induced fatality><COVID19 induced mortality><COVID19 infection><COVID19 monitoring><COVID19 mortality><COVID19 patient><COVID19 positive patient><COVID19 related death><COVID19 related fatality><COVID19 related mortality><CV-19><California><Catchment Area><Cessation of life><Chronic Disease><Chronic Illness><Clinic><Clinical><Cluster randomization trial><Cluster randomized trial><Collaborations><Communication><Communities><Community Health Aides><Conditioning Therapy><Coronavirus Infectious Disease 2019><County><Death><Death Rate><Department of Health and Human Services><Disparities><Disparity><Education><Educational aspects><Effectiveness><Effectiveness of Interventions><Environment><FDA EUA><FDA Emergency Use Authorization><Family Health><Family health status><Federally Qualified Health Center><Food and Drug Administration EUA><Food and Drug Administration Emergency Use Authorization><Future><Government><Health><Health Educators><Health behavior><Home><Household><Implementation assessment><Impoverished><Infrastructure><Intervention><Intervention Strategies><Jobs><Latin America><Latino><Latino Population><Latino group><Latino individual><Latino people><Latinos><Low income><Mental Health><Mental Hygiene><Minority-Serving Institution><Misinformation><Modeling><Morbidity><Morbidity - disease rate><Neighborhoods><Occupations><Outcome><Patients><Population><Position><Positioning Attribute><Poverty><Primary Care Physician><Professional Positions><Program Acceptability><Psychological Health><Public Health><QOL><Quality of life><Randomized><Research><Resistance><Risk><SARS-CoV-2 associated death><SARS-CoV-2 associated fatality><SARS-CoV-2 associated mortality><SARS-CoV-2 death><SARS-CoV-2 fatality><SARS-CoV-2 induced death><SARS-CoV-2 induced fatality><SARS-CoV-2 induced mortality><SARS-CoV-2 infected patient><SARS-CoV-2 infection><SARS-CoV-2 monitoring><SARS-CoV-2 mortality><SARS-CoV-2 patient><SARS-CoV-2 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academic partnership><community academic research partnership><community health worker><community intervention><community level intervention><community partners><community spread><community transmission><community university partnership><community-based intervention><community-based partners><community-level spread><community-level transmission><coronavirus disease 2019><coronavirus disease 2019 associated death><coronavirus disease 2019 associated fatality><coronavirus disease 2019 associated mortality><coronavirus disease 2019 death><coronavirus disease 2019 fatality><coronavirus disease 2019 induced death><coronavirus disease 2019 induced fatality><coronavirus disease 2019 induced mortality><coronavirus disease 2019 infected patient><coronavirus disease 2019 infection><coronavirus disease 2019 monitoring><coronavirus disease 2019 mortality><coronavirus disease 2019 patient><coronavirus disease 2019 positive patient><coronavirus disease 2019 related death><coronavirus disease 2019 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evaluation><effectiveness testing><emergency use authorization><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><evaluate effectiveness><evaluate implementation><evaluation of implementation><examine effectiveness><experience><fatality due to COVID-19><fatality due to COVID19><fatality due to SARS-CoV-2><fatality due to coronavirus disease 2019><fatality due to severe acute respiratory syndrome coronavirus 2><flexibility><flexible><group intervention><health care service><health related behavior><healthcare service><high risk group><high risk individual><high risk people><high risk population><homes><implementation evaluation><implementation fidelity><implementation outcomes><implementation process><improved><infected with COVID-19><infected with COVID19><infected with SARS-CoV-2><infected with SARS-CoV2><infected with coronavirus disease 2019><infected with severe acute respiratory syndrome coronavirus 2><infection rate><innovate><innovation><innovative><interventional strategy><minority institution><model design><mortality due to COVID-19><mortality due to COVID19><mortality due to SARS-CoV-2><mortality due to coronavirus disease 2019><mortality due to severe acute respiratory syndrome coronavirus 2><mortality rate><mortality ratio><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><novel><pandemic><pandemic disease><patient infected with COVID><patient infected with COVID-19><patient infected with SARS-CoV-2><patient infected with coronavirus disease><patient infected with coronavirus disease 2019><patient infected with severe acute respiratory syndrome coronavirus 2><patient outreach><patient with COVID><patient with COVID-19><patient with COVID19><patient with SARS-CoV-2><patient with coronavirus disease><patient with coronavirus disease 2019><patient with severe acute respiratory distress syndrome coronavirus 2><physical conditioning><physical health><psychosocial><racial minority group><racial minority individual><racial minority people><racial minority population><randomisation><randomization><randomly assigned><rate of infection><resistant><risk associated with COVID-19><risk factor associated with COVID-19><risk factor related to COVID-19><risk related to COVID-19><secondary outcome><severe acute respiratory syndrome coronavirus 2 associated death><severe acute respiratory syndrome coronavirus 2 associated fatality><severe acute respiratory syndrome coronavirus 2 associated mortality><severe acute respiratory syndrome coronavirus 2 death><severe acute respiratory syndrome coronavirus 2 fatality><severe acute respiratory syndrome coronavirus 2 induced death><severe acute respiratory syndrome coronavirus 2 induced fatality><severe acute respiratory syndrome coronavirus 2 induced mortality><severe acute respiratory syndrome coronavirus 2 infected patient><severe acute respiratory syndrome coronavirus 2 monitoring><severe acute respiratory syndrome coronavirus 2 mortality><severe acute respiratory syndrome coronavirus 2 patient><severe acute respiratory syndrome coronavirus 2 positive patient><severe acute respiratory syndrome coronavirus 2 related death><severe acute respiratory syndrome coronavirus 2 related fatality><severe acute respiratory syndrome coronavirus 2 related mortality><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><uptake><vaccinate against COVID-19><vaccinate against SARS-CoV-2><vaccinate against coronavirus disease 2019><vaccinate against severe acute respiratory syndrome coronavirus 2><vaccination acceptability><vaccination acceptance><vaccination against COVID-19><vaccination against SARS-CoV-2><vaccination against Severe acute respiratory syndrome coronavirus 2><vaccination against coronavirus disease 2019><vaccination confidence><vaccination uptake><vaccination willingness><vaccine acceptability><vaccine acceptance><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine candidates against SARS-CoV-2><vaccine confidence><vaccine for novel coronavirus><vaccine uptake><vaccine willingness><vaccines preventing COVID><vaccines to prevent COVID>