Document text
Principal Investigator: John Kablan
Organization: INNOVATIVE DESIGN LABS, INC.
Fiscal Year: 2024
Award: $1,249,991
Funding agency: National Institute on Aging
Project Summary/Abstract
Proposed is a sleep monitoring system specifically designed for care providers of persons with Alzheimer’s
disease and Alzheimer’s Disease Related Dementias (AD/ADRD) to monitor sleep disturbances and trends.
Significance: Studies indicate that approximately 1 in 3 patients with AD/ADRD suffer from sleep and other
nighttime disturbances such as insomnia and disruption of sleep, wandering, day/night confusion, repeatedly
leaving bed, nightmares, and hallucinations. Sleep disturbances often lead to reduced health and lower quality
of life for persons with AD/ADRD and in Long Term Care (LTC) settings place burden on staff. Nearly half of all
people in LTC settings have a diagnosis of AD/ADRD. Unfortunately, clinical providers and staff in LTCs are
limited in their ability to identify and treat these conditions as current methods of sleep quality assessment are
either inaccurate, time consuming, or inappropriate for use with those who have AD/ADRD. Hypothesis: We
hypothesize that a system which allows for practical, long-term monitoring of sleep quality metrics for patients
with AD/ADRD will lead to greater documentation of sleep problems, greater prescribing of appropriate
nonpharmacological treatment, and improvements in sleep quality and daytime inactivity. Specific Aims: To
transition the Phase I prototype to a production ready product and evaluate the efficacy of the system in Phase
II IDL will 1) Create production-ready system with updated hardware, firmware, and mechanical design 2)
Create cloud-enabled backend, implement web / mobile interfaces, and refine sleep metrics and 3) Evaluate
system’s real-world feasibility, acceptability, and utility in a before-after clinical trial.
Terms: <AD dementia><AD related dementia><ADRD><Acoustics><Adherence><Admission><Admission activity><Aging><Algorithms><Alzheimer Type Dementia><Alzheimer disease dementia><Alzheimer sclerosis><Alzheimer syndrome><Alzheimer's><Alzheimer's Disease><Alzheimer's and related dementias><Alzheimer's diagnosis><Alzheimer's disease and related dementia><Alzheimer's disease and related disorders><Alzheimer's disease diagnosis><Alzheimer's disease or a related dementia><Alzheimer's disease or a related disorder><Alzheimer's disease or related dementia><Alzheimer's disease patient><Alzheimer's disease related dementia><Alzheimer's patient><Alzheimers Dementia><Amentia><American><Beds><Body Measures><Body measure procedure><Care Givers><Caregivers><Caring><Cell Communication and Signaling><Cell Signaling><Clinic><Clinical><Clinical Trials><Clothing><Collaborations><Computer software><Confusion><Confusional State><Consult><Consumption><Custom><Data><Data Bases><Databases><Dementia><Dementia caregivers><Development><Devices><Documentation><Ecologic Monitoring><Ecological Monitoring><Education><Educational aspects><Electronics><Environmental Factor><Environmental Monitoring><Environmental Risk Factor><Event><Faculty><Feedback><HIPAA><Hallucinations><Health><Health Care Providers><Health Facilities><Health Insurance Portability and Accountability Act><Health Personnel><Health care facility><Healthcare Facility><Healthcare Providers><Healthcare worker><Indiana><Individual><Insomnia><Insomnia Disorder><Institution><Institutionalization><Internet><Intervention><Intervention Strategies><Intervention Studies><Intracellular Communication and Signaling><Kennedy Kassebaum Act><Lead><Light><Long-Term Care><Mattresses><Measures><Mechanics><Medicine><Mental Confusion><Methods><Minnesota><Monitor><Movement><NIH><National Institutes of Health><Neurology><Nightmare><Non-pharmacologic Therapy><Nonpharmacologic Intervention><Nonpharmacologic Therapy><Nonpharmacologic approach><Nonpharmacologic treatment><PL 104-191><PL104-191><Participant><Patients><Pb element><Persons><Phase><Phase Transition><Phone><Photoradiation><Physiologic pulse><Polysomnography><Population><Position><Positioning Attribute><Prevalence><Primary Senile Degenerative Dementia><Production><Provider><Public Health><Public Law 104-191><Pulse><QOC><QOL><Quality of Care><Quality of life><Radar><Reporting><Research><Risk><SBIR><Safety><Scientist><Signal Transduction><Signal Transduction Systems><Signaling><Skin><Sleep><Sleep Disorders><Sleep Monitoring><Sleep disturbances><Sleeplessness><Small Business Innovation Research><Small Business Innovation Research Grant><Software><Somnography><Stress><System><Technology><Telephone><Temperature><Testing><Time><Transmission><United States Health Insurance Portability and Accountability Act><United States National Institutes of Health><Universities><Update><WWW><WiFi><aberrant sleep><biological signal transduction><body movement><care facilities><care providers><caregivers for persons living with dementia><caregivers for persons with dementia><caregivers of individuals with dementia><caregivers of patients with dementia><consults><cost><customized therapy><customized treatment><customs><data base><dementia care giver><design><designing><determine efficacy><developmental><disrupted sleep><disturbed sleep><efficacy analysis><efficacy assessment><efficacy determination><efficacy evaluation><efficacy examination><electronic><electronic device><environmental risk><environmental testing><evaluate efficacy><examine efficacy><experience><extended care><health care personnel><health care worker><health provider><health workforce><healthcare personnel><heavy metal Pb><heavy metal lead><impaired sleep><improved><individualized medicine><individualized patient treatment><individualized therapeutic strategy><individualized therapy><individualized treatment><innovate><innovation><innovative><interest><intervention research><interventional research><interventional strategy><interventional study><interventions research><irregular sleep><longterm care><mechanic><mechanical><medical college><medical personnel><medical schools><millimeter><mobile app><mobile application><mobile device application><non-drug therapy><non-drug treatment><nondrug therapy><nondrug treatment><online app><patient living with Alzheimer's disease><patient specific therapies><patient specific treatment><patient suffering from Alzheimer's disease><patient with Alzheimer's><patient with Alzheimer's disease><polysomnographic><primary degenerative dementia><programs><prototype><quality of sleep><remote monitoring><school of medicine><senile dementia of the Alzheimer type><sensor><signal processing><sleep diseases><sleep disruption><sleep dysfunction><sleep dysregulation><sleep illness><sleep measurement><sleep polysomnography><sleep problem><sleep quality><success><tailored medical treatment><tailored therapy><tailored treatment><transmission process><treatment provider><trend><unique treatment><web><web app><web application><web based app><web based application><web based interface><wi-fi><wireless fidelity><world wide web>