Document text
Principal Investigator: J DOUGLAS COATSWORTH
Organization: UNIVERSITY OF TENNESSEE KNOXVILLE
Fiscal Year: 2020
Award: $125,036
Funding agency: National Institute on Drug Abuse
The novel coronavirus disease (COVID-19) pandemic of 2020 has disrupted normal daily functioning for
people across the globe as governments have sought to limit community spread of the disease. Because the
virus affects the respiratory tract, individuals with compromised lung function, such as those with COPD or lung
disease associated with smoking or vaping may also be at elevated risk. Preliminary evidence suggests that
smokers are at higher risk for severe COVID-19 illness and death (Guan et al., 2020). Public health messages
urge people to quit smoking (Forster, 2020, and the World Health Organization recommends not smoking or
using other substances to cope with stress during the pandemic (WHO, 2020). At the same time, studies
indicate that individuals are likely in increase their smoking, alcohol intake and substance use during periods of
high stress or traumatic events such as Hurricane Katrina or 911 (Flory et al., 2009). Given the urgency and
stressful nature of this pandemic, there is a critical need for research investigating the influence of the
pandemic on cannabis and tobacco smoking/vaping and other substance use. Directly building upon our
NIDA-funded (1 R01 DA044206-01A1, Treating young adult cannabis use disorder with text messageddelivered
Peer Network Counseling) RCT, we propose to follow a sample of 262 young adults from Tennessee
(n = 139) and Colorado (n = 123) who screened positive for cannabis use disorder (CUD) and participated in a
sub-study named the Cannabis Culture Study. Participants completed surveys about cannabis use behaviors,
cannabis use motivations, and cannabis use attitudes between January 9 and February 3, 2020, immediately
prior to increases in media attention and public health regulations regarding COVID-19. We propose to
capitalize on this longitudinal natural experiment to understand the health risk effects of the COVID-19
pandemic on young adults with cannabis use disorder by assessing participants every 3 months for 24 months.
Because the funded RCT will also be conducted during the naturally occurring socio-economic and personal
changes in response to the COVID-19 pandemic, this sample of youth will provide a natural comparison group
of how youths’ cannabis use attitudes and behaviors change in the context of COVID-19 but outside the
experimental intervention activities. Our specific aims are:
Aim1: Examine changes in cannabis, tobacco smoking/vaping, and other substance use as a function
of the COVID-19 pandemic among young adults meeting criteria for CUD.
Aim2: Examine mediated pathways by which COVID-19 pandemic affect changes in cannabis, tobacco
smoking/vaping, and other substance use.
Aim3: Examine whether the mediated pathways by which COVID-19 pandemic affect changes in
cannabis, tobacco smoking/vaping, and other substance use are conditioned on sex and state
residence.
Terms: <2019 novel coronavirus><2019-nCoV><AOD use><Address><Affect><Age><Alcohol Drinking><Alcohol consumption><Alcohol or Other Drugs use><Anxiety><Attention><Attitude><Behavior><Belief><CDC><COPD><COVID><COVID-19><COVID-19 epidemic><COVID-19 pandemic><COVID19><COVID19 epidemic><COVID19 pandemic><Cannabis><Cannabis Smoking><Centers for Disease Control><Centers for Disease Control and Prevention><Centers for Disease Control and Prevention (U.S.)><Cessation of life><China><Chronic Obstruction Pulmonary Disease><Chronic Obstructive Airway Disease><Chronic Obstructive Lung Disease><Chronic Obstructive Pulmonary Disease><CoV disease><CoV emergence><Colorado><Communities><Contracting Opportunities><Contracts><Counseling><Data><Death><Disease><Disease Outbreaks><Disorder><Distress><EtOH drinking><EtOH use><Family><Funding><Government><Handwashing><Health><Hurricane><Individual><Intervention><Intervention Strategies><Knowledge><Life><Location><Lung diseases><Mainland China><Marijuana Smoking><Measurement><Mediating><Mental Depression><Motivation><NIDA><Names><National Institute of Drug Abuse><National Institute on Drug Abuse><Natural experiment><Nature><Neural Development><Outbreaks><Parents><Participant><Pathway interactions><Pattern><Peer Group><Persons><Population><Public Health><Pulmonary Body System><Pulmonary Diseases><Pulmonary Disorder><Pulmonary Organ System><Recommendation><Regulation><Reporting><Research><Respiratory Disease><Respiratory System><Respiratory System Disease><Respiratory System Disorder><Respiratory Tracts><Respiratory physiology><Respiratory tract structure><Risk><SARS-CoV-2><SARS-CoV2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-related coronavirus 2><Sampling><Schools><Severe acute respiratory syndrome coronavirus 2><Smoker><Smoking><Social Change><Social Distance><Social isolation><Social modification><Social transformation><Stress><Substance Use Disorder><Survey Instrument><Surveys><THC co-use><THC use><Tennessee><Testing><Tetrahydrocannabinol co-use><Tetrahydrocannabinol use><Text><Text Messaging><Time><Tobacco smoke><Tobacco smoking><Tobacco smoking behavior><United States Centers for Disease Control><United States Centers for Disease Control and Prevention><Urinalysis><Viral Pneumonia><Virus><World Health Organization><Wuhan coronavirus><Youth><Youth 10-21><addiction><addictive disorder><adult youth><ages><alcohol ingestion><alcohol intake><alcohol product use><alcohol use><alcoholic beverage consumption><alcoholic drink intake><anxiety symptoms><anxious symptom><behavior change><behavior influence><behavioral influence><cannabis use><cannabis use disorder><cease smoking><comparator group><comparison group><corona virus disease><corona virus disease 2019><corona virus disease 2019 epidemic><corona virus disease 2019 pandemic><coronavirus disease><coronavirus disease 2019><coronavirus disease 2019 epidemic><coronavirus disease 2019 pandemic><coronavirus emergence><daily functioning><depression><design><designing><disease of the lung><disorder of the lung><emergent CoV><emergent coronavirus><emerging CoV><emerging coronavirus><environmental change><ethanol consumption><ethanol drinking><ethanol ingestion><ethanol intake><ethanol product use><ethanol use><experience><food insecurity><hand washing><high risk><indexing><insight><interventional strategy><lung disorder><lung function><marijuana use><marijuana use disorder><meetings><nCoV><neurodevelopment><new CoV><new coronavirus><novel CoV><novel coronavirus><pandemic><pandemic disease><pathway><peer><peer networks><psychiatric symptom><psychologic><psychological><quit smoking><residence><residential building><residential site><respiratory function><response><sex><short message service><smoking cessation><socio-economic><socio-economically><socioeconomically><socioeconomics><stop smoking><substance use><substance using><symptomatology><texting><traumatic event><using substances><vaping><young adult><young adulthood>