Document text
Principal Investigator: Ashley Comiford
Organization: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
Fiscal Year: 2024
Award: $175,285
Funding agency: National Institute on Minority Health and Health Disparities
Project Summary/Abstract
American Indian/Alaska Native (AI/AN) populations were disproportionately affected by the COVID-19
pandemic compared to other racial/ethnic populations. AI/AN individuals experience a higher prevalence of
chronic diseases that increase risk of COVID-19 complications including cancer, diabetes, chronic liver
disease, chronic lung diseases, cardiovascular diseases, asthma, and obesity, and have higher rates of
smoking compared to other racial/ethnic groups. The COVID-19 pandemic created unprecedented
interruptions in necessary services, including healthcare, in response to social distancing mandates
implemented to reduce the transmission of the virus. Health care services were further disrupted due to the
necessary shift of clinical and hospital resources to COVID-19 patients. It remains unknown whether changes
in healthcare access for AI/AN people or chronic health conditions impacted uptake of COVID-19 testing and
vaccination and whether these changes differed by geography and sociodemographic factors (e.g., rurality and
area deprivation). There is, therefore, a critical need to understand the extent to which the pandemic influenced
access to healthcare and whether individuals with chronic health conditions had barriers to receiving COVID-
19 testing and vaccination. Our long-term goal is to improve access to COVID-19 testing and vaccination
among AI/AN people, particularly among those with chronic health conditions. Our overall objective of this
application is to analyze RADx-UP consortium data to evaluate the impact of the COVID-19 pandemic on
AI/AN RADx-UP participants with chronic health conditions, changes in access to healthcare, and
sociodemographic factors on COVID-19 testing and vaccination uptake. We aim to identify whether chronic
health conditions, healthcare access, and sociodemographic factors impacted 1) access to COVID-19 testing
and 2) access to COVID-19 vaccination among AI/AN persons. Upon successful completion of this project, the
expected outcomes are that we will have identified barriers to COVID-19 testing and vaccination uptake among
AI/AN RADx-UP participants with chronic health conditions, challenged healthcare access, and poor
sociodemographic factors. These results are expected to have a positive impact because empirical evidence of
barriers to COVID-19 testing and harmonization among high-risk populations will allow for development of
intervention strategies to improve health outcomes in this underserved population.
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pandemic impact><COVID-19 pandemic impacted><COVID-19 patient><COVID-19 period><COVID-19 positive patient><COVID-19 public health crisis><COVID-19 related complications><COVID-19 related risk><COVID-19 risk><COVID-19 risk factor><COVID-19 testing><COVID-19 vaccination><COVID-19 vaccine><COVID-19 years><COVID19 patient><COVID19 positive patient><COVID19 testing><Cancers><Cardiovascular Diseases><Check-up><Cherokee><Cherokee Indian><Cherokee Nation><Choctaw><Chronic><Chronic Disease><Chronic Illness><Chronic lung disease><Clinical><Common Data Element><Communities><Data><Data Collection><Development><Diabetes Mellitus><Ensure><Ethnic Group><Ethnic People><Ethnic Population><Ethnic individual><Ethnicity People><Ethnicity Population><Funding><Geography><Goals><Health><Health Sciences><Health Services Accessibility><Healthcare><High Prevalence><Hospitals><Improve Access><Individual><Interruption><Intervention><Intervention Strategies><Investigators><Knowledge><Malignant Neoplasms><Malignant Tumor><Native Americans><Obesity><Oklahoma><Outcome><Participant><Physical distancing><Preventative health care><Preventative healthcare><Preventive health care><Preventive healthcare><RADx Underserved Populations><RADx-UP><Race><Races><Racial Group><Rapid Acceleration in Diagnostics for Underserved Populations><Rapid Acceleration of Diagnostics Underrepresented Persons><Rapid Acceleration of Diagnostics Underserved Populations><Research><Research Personnel><Research Resources><Researchers><Resources><Rural><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 infected patient><SARS-CoV-2 pandemic><SARS-CoV-2 patient><SARS-CoV-2 positive patient><SARS-CoV-2 testing><SARS-CoV-2 vaccination><SARS-CoV-2 vaccine><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-coronavirus-2 vaccine><Screening for cancer><Services><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome CoV 2 vaccine><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome coronavirus 2 vaccination><Severe acute respiratory syndrome coronavirus 2 vaccine><Site><Smoking><Social Distance><Underserved Population><Universities><Vaccination><Vaccines><Work><accept vaccination><accept vaccine><access to health care><access to health services><access to healthcare><access to services><access to treatment><accessibility of health care><accessibility to health care><accessibility to health services><accessibility to healthcare><adiposity><availability of services><cardiovascular disorder><care access><checkup><checkup examination><chronic disorder><chronic hepatic disease><chronic hepatic disorder><chronic liver disease><chronic liver disorder><chronic pulmonary disease><complications due to COVID-19><coronavirus disease 2019 consequence><coronavirus disease 2019 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impact><coronavirus disease-19 pandemic><coronavirus disease-19 patient><coronavirus disease-19 vaccine><coronavirus patient><coronavirus testing><corpulence><data harmonization><deprivation><develop therapy><developmental><diabetes><disease diagnosis><disparity in health><early cancer detection><effective intervention><effects following the COVID-19 pandemic><ethnic subgroup><ethnicity group><experience><harmonized data><health care><health care access><health care availability><health care service><health care service access><health care service availability><health disparity><health service access><health services availability><healthcare access><healthcare accessibility><healthcare availability><healthcare service><healthcare service access><healthcare service availability><high risk group><high risk individual><high risk people><high risk population><impact of the SARS-CoV-2 pandemic><implementation strategy><improved><intersectionalities><intersectionality><intervention development><interventional strategy><malignancy><nCoV vaccine><nCoV-19 vaccine><nCoV19 vaccine><neoplasm/cancer><pandemic><pandemic disease><patient infected with COVID><patient infected with COVID-19><patient infected with SARS-CoV-2><patient infected with coronavirus disease><patient infected with coronavirus disease 2019><patient infected with severe acute respiratory syndrome coronavirus 2><patient with COVID><patient with COVID-19><patient with COVID19><patient with SARS-CoV-2><patient with coronavirus disease><patient with coronavirus disease 2019><patient with severe acute respiratory distress syndrome coronavirus 2><racial><racial background><racial origin><racial population><racial subgroup><residence><residential building><residential site><response><risk associated with COVID-19><risk factor associated with COVID-19><risk factor related to COVID-19><risk related to COVID-19><rurality><screening cancer patients><service availability><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><severe acute respiratory syndrome coronavirus 2 infected patient><severe acute respiratory syndrome coronavirus 2 patient><severe acute respiratory syndrome coronavirus 2 positive patient><severe acute respiratory syndrome coronavirus 2 testing><socio-demographic factors><socio-demographics><sociodemographic factors><sociodemographics><strategies for implementation><testing for COVID><testing of COVID><testing uptake><therapy development><treatment access><treatment development><tribal community><under served group><under served individual><under served people><under served population><underserved group><underserved individual><underserved people><uptake><vaccinate against COVID-19><vaccinate against SARS-CoV-2><vaccinate against coronavirus disease 2019><vaccinate against severe acute respiratory syndrome coronavirus 2><vaccination acceptability><vaccination acceptance><vaccination against COVID-19><vaccination against SARS-CoV-2><vaccination against Severe acute respiratory syndrome coronavirus 2><vaccination against coronavirus disease 2019><vaccination confidence><vaccination uptake><vaccination willingness><vaccine acceptability><vaccine acceptance><vaccine against 2019-nCov><vaccine against COVID-19><vaccine against SARS-CoV-2><vaccine against SARS-coronavirus-2><vaccine against Severe Acute Respiratory Syndrome CoV 2><vaccine against Severe acute respiratory syndrome coronavirus 2><vaccine candidates against SARS-CoV-2><vaccine confidence><vaccine for novel coronavirus><vaccine uptake><vaccine willingness><vaccines preventing COVID><vaccines to prevent COVID><viral transmission><virus transmission>