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Principal Investigator: Ivan H Wu
Organization: UNIVERSITY OF MINNESOTA
Fiscal Year: 2024
Award: $232,026
Funding agency: National Institute on Minority Health and Health Disparities
PROJECT SUMMARY/ABSTRACT
The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behav-
iors among African Americans (AAs), given the high disease burdens associated with low physical activity, in-
sufficient sleep, and obesity. To this end, the candidate will seek to understand how social contextual factors
impact sleep by using qualitative interviews and an existing quantitative data sets (K99). Knowledge gained
from the K99 phase will inform the adaptation and testing of an existing sleep intervention (MDACC IRB Proto-
col #2018-0568) (R00). During the K99 phase, the candidate will receive focused and intensive training involv-
ing workshops, courses, lectures, and directed readings from renowned experts in the fields of health dispari-
ties, sleep medicine, and obesity. Two studies will include: (Aim 1) conducting qualitative in-depth interviews to
elucidate social contextual influences on sleep, while soliciting feedback to adapt a sleep intervention among
obese, sedentary, and short-sleeping AA adults; and (Aim 2) empirically testing the associations between so-
cial contextual factors, sleep, physical activity, and body weight using data from an ongoing studies of AAs
(Project FAITH; American Cancer Society, RSG-17-158-01; PI: Dr. McNeill, mentor). Lastly, during the R00
phase will compile the knowledge gained in the K99 phase to adapt a sleep intervention and test its feasibility,
satisfaction, and preliminary efficacy in improving sleep, increasing physical activity, and decreasing sedentary
behavior among overweight/obese, sedentary, and sleep-deprived AA adults (Aim 3). The candidate is
uniquely positioned to complete the proposed research based on his past clinical experience in treating insom-
nia and his research on sleep and obesity among AAs. The sleep intervention is a promising and innovative
approach to optimizing psychological and physical wellness to reduce obesity and cancer-related health dis-
parities – a research priority at the National Institute on Minority Health and Health Disparities. Furthermore,
the proposed training plan will be critical in expediting the candidate’s transition to an independent investigator
with focused expertise in developing culturally informed interventions to reduce cancer health disparities
among AAs.
Terms: <21+ years old><Address><Adult><Adult Human><Affect><African American><African American Females><African American Women><African American group><African American individual><African American people><African American population><African Americans><Afro American><Afroamerican><American Cancer Society><Application Context><BMI><BMI percentile><BMI z-score><Behavior><Belief><Body Weight><Body mass index><Cancers><Chronic><Chronic Disease><Chronic Illness><Church><Clinical><Clinical Trials Design><Communities><Conflict><Conflict (Psychology)><Data><Data Analytics><Data Set><Dedications><Development><Diabetes Mellitus><Diagnosis><Diet><Disadvantaged><Disease><Disorder><Disparities><Disparity><Educational workshop><Exposure to><Faith><Family><Fatigue><Feedback><Goals><Health><Health Campaign><Health behavior><IRB><IRBs><Individual><Individuals from minority><Individuals of minority><Insomnia><Insomnia Disorder><Institutional Review Boards><Intervention><Intervention Strategies><Interview><Investigators><Knowledge><Lack of Energy><Link><MDACC><Malignant Neoplasms><Malignant Tumor><Mediating><Medicine><Mentors><Methods><Minority Groups><Minority People><Minority Population><Minority individual><Morbidity><Morbidity - disease rate><NCMHD><NIMHD><National Center on Minority Health and Health Disparities><National Institute of Minority Health and Health Disparities><National Institute on Minority Health and Health Disparities><Neighborhoods><Obesity><Obesity associated cancer><Obesity related cancer><Over weight><Overweight><Pathway interactions><Perception><Phase><Physical activity><Position><Positioning Attribute><Protocol><Protocols documentation><Psychologist><Public Health><Quetelet index><Racial Group><Recommendation><Reporting><Research><Research Methodology><Research Methods><Research Personnel><Research Priority><Researchers><Risk><Risk Factors><Role><Sample Size><Sampling><Sedentary behavior><Sedentary life-style><Sleep><Sleep Deprivation><Sleep disturbances><Sleeplessness><Social Environment><Social support><Spirituality><Stress><Testing><Training><University of Texas M D Anderson Cancer Center><University of Texas MD Anderson Cancer Center><Work><Workshop><aberrant sleep><adiposity><adulthood><burden of disease><burden of illness><cancer disparity><cancer health disparity><cancer-related health disparity><chronic disorder><cohort><community level disadvantage><contextual factors><corpulence><culturally adapted intervention><culturally appropriate intervention><culturally centered intervention><culturally focused intervention><culturally informed intervention><culturally responsive intervention><culturally tailored intervention><deficient sleep><design><designing><developmental><diabetes><diets><disadvantaged community><disease burden><disparities in morbidity><disparities in mortality><disparity gap><disparity in cancer><disparity in health><disrupted sleep><disturbed sleep><energy balance><equity gap><ethnic minority><ethnic minority group><ethnic minority individual><ethnic minority people><ethnic minority population><experience><feasibility testing><gap in equity><gap in inequality><gap in inequity><health disparity><health related behavior><healthy life-style><healthy lifestyle><impaired sleep><improved><improvement on sleep><inadequate sleep><inequality gap><inequitable gap><inequity gap><innovate><innovation><innovative><insufficient sleep><interventional strategy><irregular sleep><lectures><malignancy><member><men><morbidity disparities><mortality><mortality disparity><neighborhood barrier><neighborhood disadvantage><neighborhood-level barrier><neighborhood-level disadvantage><neoplasm/cancer><obesity intervention><obesity risk><obesity therapy><obesity treatment><pathway><poor sleep><protective factors><psychologic><psychological><quality of sleep><racial minority><racial minority group><racial minority individual><racial minority people><racial minority population><racial population><racial subgroup><research and methods><risk for obesity><risk of obesity><satisfaction><sedentary><sedentary lifestyle><sleep debt><sleep deficiency><sleep deficit><sleep disruption><sleep dysregulation><sleep improvement><sleep insufficiency><sleep loss><sleep quality><social climate><social context><social determinants><social role><social support network><sociodeterminant><socioenvironment><socioenvironmental><trend>