Document text
Principal Investigator: Michael L. LeBlanc
Organization: FRED HUTCHINSON CANCER CENTER
Fiscal Year: 2024
Award: $8,319,732
Funding agency: National Cancer Institute
Project Summary/Abstract
Overall Component
The SWOG Statistics and Data Management Center (SDMC) provides leadership in the statistical design, data
management, analysis, and reporting of NCTN clinical trials. It contributes to SWOG's overall mission to
significantly improve lives through cancer clinical trials and translational research.
The goals of the SDMC are to (a) rapidly design, develop, and implement rigorous and efficient multi-center
clinical trials; (b) enhance systems for best monitoring of ongoing trials and ensure reproducibility of research
using cross-study standardized software and systems for statistical analysis and clinical trials reporting; (c)
develop innovative statistical design and software tools for incorporating integral and integrated biomarkers into
clinical trials; (d) collaborate with other researchers on statistical methods research, including clinical trial design
and the analysis of translational medicine studies, with a focus on precision medicine and challenges in the
evaluation of immunotherapy; (e) investigate new strategies for enhancing NCTN data by constructing linkages
to external databases and building a comprehensive repository of SWOG clinical and translational medicine
data; and (f) advance the science of the NCTN program and the National Cancer Institute research agenda, in
partnership with other NCTN investigators, by providing scientific leadership through participation in activities
such as steering committees, working groups, task forces, data sharing, and clinical science meetings.
The SWOG SDMC contributes to the goals of SWOG and partners with the NCTN to conduct trials within the
current portfolio, while also providing data, strategies, and useful new statistical tools to other clinical trials
organizations and oncology researchers.
Terms: <Advisory Committees><Biological Markers><Cancer Patient><Cancer Treatment><Cessation of life><Clinical Medical Sciences><Clinical Medicine><Clinical Sciences><Clinical Trials><Clinical Trials Design><Collaborations><Collection><Computer Software Tools><Computer software><Conduct Clinical Trials><Data><Data Bases><Data Coordinating Center><Data Coordination Center><Data Science><Databases><Death><Ensure><Evaluation><Fostering><Funding><Goals><Health Insurance for Aged and Disabled, Title 18><Health Insurance for Disabled Title 18><Immune mediated therapy><Immunologically Directed Therapy><Immunotherapy><International><Investigators><Leadership><Link><Malignant Neoplasm Therapy><Malignant Neoplasm Treatment><Medicare><Mentors><Methodology><Mission><Monitor><Morbidity><Morbidity - disease rate><Multi-Institutional Clinical Trial><Multi-center clinical trial><Multi-center trial><Multi-site clinical trial><Multicenter Trials><Multicenter clinical trial><Multisite clinical trial><NCI Organization><National Cancer Institute><Oncology><Oncology Cancer><Patient outcome><Patient-Centered Outcomes><Patient-Focused Outcomes><Patients><Phase><Publications><Reporting><Reproducibility><Research><Research Institute><Research Methodology><Research Methods><Research Personnel><Researchers><SWOG><Science><Scientific Publication><Software><Software Tools><Southwest Oncology Group><Standardization><Statistical Data Analyses><Statistical Data Analysis><Statistical Data Interpretation><Statistical Methods><System><Task Forces><Title 18><Translational Research><Translational Science><advisory team><anti-cancer research><anti-cancer therapy><bio-markers><biologic marker><biomarker><cancer clinical trial><cancer research><cancer therapy><cancer-directed therapy><clinical translation><clinical trial analysis><clinically translatable><data base><data management><data management and coordinating center><data management center><data sharing><depository><design><designing><health insurance for disabled><immune therapeutic approach><immune therapeutic interventions><immune therapeutic regimens><immune therapeutic strategy><immune therapy><immune-based therapies><immune-based treatments><immuno therapy><improved><indexing><innovate><innovation><innovative><meeting><meetings><mortality><new approaches><novel approaches><novel strategies><novel strategy><oncology clinical trial><outreach><patient oriented outcomes><phase 3 trial><phase III trial><precision medicine><precision-based medicine><programs><repository><research and methods><software toolkit><statistic methods><statistical analysis><statistics><tool><translation research><translational investigation><translational medicine><trial design><work group><working group>