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Principal Investigator: William Elkins
Organization: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Fiscal Year: 2022
Award: $28,533
Funding agency: National Institute of Allergy and Infectious Diseases
IDPS continues to support ongoing the Vaccine Research Centers (VRC) COVID-19 studies in the establishment and continued advancement of pre-exposure and post-exposure treatment modality (i.e. vaccine) studies using the rhesus macaque animal model. As a result, IDPS personnel were co-authors on 7 different scientific manuscripts, submitted to, accepted in, and published in peer-reviewed high impact scientific journals (the manuscripts are provided in the historical report). Additionally, in collaboration with the Vaccine Branch, Center for Cancer Research, National Cancer Institute, the IDPS continues to support novel vaccine safety and efficacy treatments (e.g., intranasal vaccines) through histopathologic examination and immunohistochemical studies of the nares, trachea, and lung of COVID-19 hamsters.
Terms: <2019-nCoV variant><2019-nCoV variant forms><2019-nCoV variant strains><Animal Model><Animal Models and Related Studies><COVID><COVID-19><COVID-19 variant><COVID-19 variant forms><COVID-19 variant strains><COVID19><CV-19><CV19><Center for Cancer Research><CoV disease><Collaborations><Cricetinae><Effectiveness><Hamsters><Hamsters Mammals><Human Resources><IDP><Inosine Diphosphate><Inosine Pyrophosphate><Intramuscular><Investigators><Journals><Lung><Lung Respiratory System><M mulatta><M. mulatta><Macaca mulatta><Magazine><Manpower><Manuscripts><Methods><Modality><Modeling><Moderna COVID-19 vaccine><Moderna coronavirus disease 2019 vaccine><NCI Center for Cancer Research><NCI Organization><NIAID><National Cancer Institute><National Institute of Allergy and Infectious Disease><Peer Review><Publishing><Reporting><Research Personnel><Researchers><Rhesus Macaque><Rhesus Monkey><Riboxin><Riboxine><SARS-CoV-2 variant><SARS-CoV-2 variant forms><SARS-CoV-2 variant strains><Trachea><Trachea Proper><Treatment Efficacy><Vaccine Research><Vaccines><corona virus disease><corona virus disease 2019><coronavirus disease><coronavirus disease 2019><coronavirus disease 2019 variant><coronavirus disease 2019 variant forms><coronavirus disease 2019 variant strains><coronavirus disease-19><coronavirus infectious disease-19><deliver vaccines><develop a vaccine><develop vaccines><development of a vaccine><histopathologic examination><histopathological examination><intervention efficacy><mRNA-1273><mRNA1273><model of animal><model organism><new vaccines><next generation vaccines><novel vaccines><personnel><pulmonary><severe acute respiratory syndrome coronavirus 2 variant><severe acute respiratory syndrome coronavirus 2 variant forms><severe acute respiratory syndrome coronavirus 2 variant strains><therapeutic efficacy><therapy efficacy><vaccination study><vaccination trial><vaccine delivery><vaccine development><vaccine efficacy><vaccine safety><vaccine study><vaccine trial><windpipe>