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Principal Investigator: JERRY H GURWITZ
Organization: UNIV OF MASSACHUSETTS MED SCH WORCESTER
Fiscal Year: 2020
Award: $717,173
Funding agency: National Institute on Aging
PROJECT SUMMARY/ABSTRACT:
The HCSRN-OAICs AGING Initiative seeks an administrative supplement (PA-18-591/NOT-AG-20-022) to
R33AG057806 to address pressing research questions related to prevention, control, management, and
treatment of COVID-19 in nursing homes, such as: What are the characteristics of the small to modest-sized
clusters of nursing homes that are associated with the AGING Initiative partners?; What COVID-19 related
research questions, with direct applicability to the care and well-being of nursing home residents, would be of
the highest priority and most amenable to study in the context of the ongoing pandemic?; What are the current
barriers and challenges to conducting COVID-19 related research in nursing homes?; and What steps would
be required to create a nursing home clinical trials network comprised of the small to modest-sized clusters of
nursing homes that are associated with the AGING Initiative partners? The “Advancing Geriatrics Infrastructure
and Network Growth” (AGING) Initiative brings together the Health Care Systems Research Network (HCSRN)
and the OAICs to advance an interdisciplinary research agenda focused on older adults with multiple chronic
conditions (MCCs). The specific aims under the AGING Initiative R33 are: (1) to expand on and further develop
innovative methods related to measurement and analytics, observational research, and pragmatic clinical trial
design and implementation, to inform the development and testing of novel interventions that improve the care
and outcomes of older persons with MCCs; (2) to foster the career development and success of new and early-
stage investigators, including underrepresented minorities; (3) to create a new core function as part of an
elaborated infrastructure that promotes patient-centered research by engaging patients and care partners in all
stages of the research process; and (4) to fund a series of “P-2-R” (“Pilot-to-R award”) grants. The proposed
administrative supplement builds on the parent project (R33AG057806) by: (1) addressing a research topic of
vital relevance to older adults with multiple chronic conditions (MCCs) – the devastating impact of novel
coronavirus 2019 (COVID-19) in nursing homes; (2) assessing new methods and approaches addressing
research questions relevant to older adults with MCCs; (3) promoting new collaborations and partnerships to
advance the science of MCCs; and (4) encouraging research that will ultimately translate into the delivery of
higher quality care for vulnerable populations including residents of nursing homes.
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