Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Heinrich Feldmann · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2023 · $341,507 — The global public health burden caused by SARS-CoV-2 and its resulting disease, COVID-19, has driven the rapid development of vaccines and treatment options. However, the continued emergence of novel SARS-CoV-2 variants of concern (VOC), which rapidly and globally replace earlier, previously predomi…
D. Rebecca Prevots · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2023 · $14,060 — Background Prior research has shown variability in household secondary attack rates (SAR) and transmission risks of SARS-CoV-2, which remains poorly understood. To address these questions, we conducted a household serologic study nested within a larger prospective cohort study of SARS-CoV-2 in Cost…
Emily Ricotta · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2023 · $1,205,774 — COVID-19 is caused by the novel SARS-CoV-2 and is associated with a hyper-inflammatory immune response which leads to severe and potentially life-threatening symptoms. Little is known about how and the extent to which COVID-19 presents in people with immunodeficiencies, but because of the known seve…
Yan Li · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · 2023 · $933,647 — PCF is equipped with a Thermo Fisher Orbitrap Lumos mass spectrometer with an nanoflow Ultimate 3000 HPLC, and an Agilent 6230 LC-TOF system. PCF seeks to provide high quality proteomics services on intact Protein molecular weight measurement; protein identification; protein quantification using l…
James Inglese · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · 2023 · $693,256 — This project includes the development of biochemical and target-focused assays based on specific protein or nucleic acid targets implicated in disease. The assay designs are considered in the context of analysis and progression strategies for evaluation of a wide range of compound classes using hi…
Matthew Wheeler · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · 2023 · $112,846 — With the increasing complexity of large datasets, the development of novel statistical techniques that can create informative analyses, which allow scientists and decision makers, to leverage the richness of the data source is needed. This research seeks to develop methodologies that extract meanin…
Wing Pui Kong · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2023 · $285,362 — Since there is no effective cure for COVID-19. Though the mRNA vaccines were authorized for emergency use, the durability of protection provided by these two mRNA vaccines is still a concern, given the fact that the spike-specific antibodies decline rapidly in convalescent sera of COVID patients. Du…
Adolfo Garcia-Sastre · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2023 · $817,413 — The objective of the Technology Core is to provide state-of-the-art, innovative -OMICs technologies for the targeted and global characterization of Project samples in a quantitative, reproducible, and efficient manner. The core brings together cutting-edge tools and the expertise of leading systems …
CALVIN J KUO · STANFORD UNIVERSITY · 2023 · $530,054 — PROJECT SUMMARY (Core B: Organoid Core) Infectious disease research is substantially hampered by lack of experimental models necessary to study interactions between pathogens and target tissues; a glaring deficiency amplified by the recent COVID-19 pandemic. The recent advent of 3D organoid methods …
Colin S. Duckett · DUKE UNIVERSITY · 2023 · $933,206 — ABSTRACT- Facility Management, Maintenance and Operations Core (Core 1) To serve the primary mission of the Duke RBL, it is imperative that the facility itself operates to the highest operational standards. The overall goal of this Aim is to ensure that we can maintain reliable and uninterrupted fac…
Rachel M Olson · UNIVERSITY OF MISSOURI-COLUMBIA · 2023 · $944,931 — Project Summary Core 3: Biocontainment Research Support Services Core The objective of the Biocontainment Research Support Services Core (BRSSC, Core 3) is to provide sustainable research resources that facilitate the pre-clinical development of medical countermeasures against emerging and re-emergi…
KAREN M RIDGE · NORTHWESTERN UNIVERSITY AT CHICAGO · 2023 · $516,586 — PROJECT SUMMARY PROJECT 1 Severe viral pneumonia, due to influenza A virus (IAV) damages the lower respiratory tract to cause acute respiratory distress syndrome (ARDS). The persistence of respiratory failure in patients with ARDS is a consequence of persistent inflammation and the failure of normal…
STEPHAN BOUR · DIGITAL INFUZION, INC. · 2023 · $277,285 — To provide processing for data collected and generated by the NIAID CEIRR program related to SARS-CoV-2.…
THOMAS DENNY · DUKE UNIVERSITY · 2023 · $1,830,201 — The mission of the Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), is to increase basic knowledge of the pathogenesis and transmission of the human immunodeficiency virus (HIV), support the development of therapies for HIV…
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2023 · $3,186,892 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
CLAIRE L MOORE · TUFTS UNIVERSITY BOSTON · 2023 · $247,500 — Determining the role of alternative mRNA polyadenylation in SARS-Cov-2 replication and the host innate immune response SARS-CoV-2 infection has caused the COVID-19 pandemic, and understanding the molecular mechanisms leading to its pathophysiology is a top biomedical priority. In spite of intense re…
Keri Nicole Althoff · JOHNS HOPKINS UNIVERSITY · 2023 · $2,035,602 — PROJECT SUMMARY Approximately half of all people with HIV (PWH) in the United States (US) have one or more mental health disorder. Ending the HIV Epidemic in the US requires addressing the mental health needs of, and improving HIV treatment outcomes for, PWH with mental health disorders. The goal of…
Tené T Lewis · EMORY UNIVERSITY · 2023 · $375,646 — PROJECT SUMMARY The novel coronavirus disease 2019 (COVID-19) global pandemic was arguably one of the most devastating Public Health crises of the last century. In the US, African-Americans have been disproportionately impacted, with overall rates of infection and mortality 2 to 4 times higher than …
Margaret L Schneider · SOCIETY OF BEHAVIORAL MEDICINE · 2023 · $65,000 — PROJECT ABSTRACT The Society of Behavioral Medicine (SBM) will hold its 44th Annual Meeting & Scientific Sessions April 26-29, 2023, in Phoenix, AZ. This application seeks funding in support of meeting programming addressing the following specific aims: (1) Train attendees in the skills necessary to…
Olga Juliana Baker · GORDON RESEARCH CONFERENCES · 2023 · $15,000 — PROJECT SUMMARY This proposal requests partial support for the thirteenth Gordon Research Conference (GRC) and the third Gordon Research Seminar (GRS) entitled Salivary Glands and Exocrine Biology: Understanding the Biology of Secretory Function and Diseases of Exocrine Tissues to be held from Back …