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9873 documents

Resources and Workforce Development for Research on NIH/NIAID High Priority Pathogens at the University of Missouri Regional Biocontainment Laboratory

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Wendy L. Picking · UNIVERSITY OF MISSOURI-COLUMBIA · 2023 · $2,595,464 — Overall Project Summary Resources and Workforce Development for Research on NIH/NIAID High Priority Pathogens at the University of Missouri Regional Biocontainment Laboratory The University of Missouri Regional Biocontainment Laboratory (RBL) was commissioned in 2009 as an $18M, 12,377 NSF BSL-3/ABS…

HPMI: Host Pathogen Mapping Initiative

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Nevan J Krogan · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2023 · $2,489,172 — THE HOST PATHOGEN MAP INITIATIVE 2.0 OVERALL SUMMARY The Host-Pathogen Map Initiative (HPMI) 2.0 is an interdisciplinary program that aims to improve our understanding of the interactions between host cellular systems and respiratory pathogens and builds upon the success of its previous iteration. T…

The Southwest National Primate Research Center

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Larry S. Schlesinger · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2023 · $73,260 — OVERALL ABSTRACT The Mission of the Southwest National Primate Research Center (SNPRC) is to improve the health of our global community through innovative biomedical research with nonhuman primates (NHPs). One way that it achieves this goal is by serving as a global resource to scientists that ca…

Society of Behavioral Medicine 2023 Annual Meeting & Scientific Sessions

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Margaret L Schneider · SOCIETY OF BEHAVIORAL MEDICINE · 2023 · $12,687 — PROJECT ABSTRACT The Society of Behavioral Medicine (SBM) will hold its 44th Annual Meeting & Scientific Sessions April 26-29, 2023, in Phoenix, AZ. This application seeks funding in support of meeting programming addressing the following specific aims: (1) Train attendees in the skills necessary to…

Center for Translational Pediatric Research

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Alan Tackett · ARKANSAS CHILDREN'S HOSPITAL RES INST · 2023 · $955,666 — Project Summary Parent award. The parent award for this supplement is associated with the Arkansas Children's Research Institute (ACRI) Center for Translational Pediatric Research (CTPR: P20GM121293-05S1). The CTPR aims to build an innovative, multi-disciplinary pediatric research center that utiliz…

Northern New England Clinical and Translational Research Network - N3C Initiative

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

CLIFFORD JAMES ROSEN · MAINEHEALTH · 2023 · $348,252 — ABSTRACT The National Covid Cohort Collaborative (N3C), sponsored by the National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (Cd2H) have created a centralized national database on a cloud-based analytic platform for scientists to use to study COVID…

Respiratory pathogen-specific T cell signatures following vaccination, natural infection, and treatment

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Alessandro Sette · LA JOLLA INSTITUTE FOR IMMUNOLOGY · 2023 · $2,391,540 — Project Summary – Overall The La Jolla HIPC team will focus on pathogens causing infectious diseases of the upper and lower respiratory tract that lead to substantial mortality and morbidity. Our approach is unique and innovative, as it focuses on defining immune signatures (IMS) of antigen-specifi…

Multivariate spatiotemporal models to quantify disparities in COVID-19 health outcomes

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Brian Neelon · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2023 · $185,516 — PROJECT SUMMARY Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has created a global public health crisis since its onset in late 2019. Although the pandemic has affected all communities, recent work suggests that socially vulnerable po…

A randomized controlled trial of smell training and trigeminal nerve stimulation in the treatment of COVID-related persistent smell loss

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Bashar W Badran · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2023 · $637,973 — ABSTRACT COVID exposed the critical need for new and improved treatment interventions for chemosensory (i.e. smell and taste) dysfunction. Evidence indicates that COVID-related smell loss (SL) often endures well past recovery of the initial infection and is highly associated with other long COVID ne…

Development of simulated 3-D virtual reality testing for baboon AD/dementia and spatial cognition research

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Larry S. Schlesinger · TEXAS BIOMEDICAL RESEARCH INSTITUTE · 2023 · $499,999 — OVERALL ABSTRACT The Mission of the Southwest National Primate Research Center (SNPRC) is to improve the health of our global community through innovative biomedical research with nonhuman primates (NHPs). One way that it achieves this goal is by serving as a global resource to scientists that ca…

Blood DNA Methylation Biomarkers of Post AcuteSequelae of SARS CoV 2 Infection (PASC)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Reid Spencer Alisch · ALBANY MEDICAL COLLEGE · 2023 · $812,430 — Project Summary: DNA 5'-C-phosphate-G-3' (CpG) methylation is a covalent epigenetic modification that regulates gene expression and is highly sensitive to age and environmental factors. Critically ill patients exhibit altered circulating blood DNA methylation profiles. We have recently reported a la…

Feasibility of conducting HIV surveillance in community wastewater

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Julie Parsonnet · STANFORD UNIVERSITY · 2023 · $231,713 — PROJECT SUMMARY At the start of the COVID-19 pandemic in late 2019, an estimated 1.2 million people—including 158,500 (13%) with undiagnosed infection—were living with HIV in the United States. Since then, HIV control efforts have been complicated by disruptions to HIV testing, care-related services…

Temple University Gastroparesis Clinical Center

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

HENRY PAUL PARKMAN · TEMPLE UNIV OF THE COMMONWEALTH · 2023 · $393,626 — PROJECT SUMMARY Patients with gastroparesis often suffer with chronic symptoms that are not adequately treated due to both a lack of understanding of the underlying pathophysiology of gastroparesis and lack of effective treatments. Participation of Temple University as a clinical center in the NIDDK…

RADx-UP CDCC

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Michael Cohen-Wolkowiez · DUKE UNIVERSITY · 2023 · $32,364,105 — ABSTRACT There is an urgent need to reduce disparities in COVID-19 associated morbidity and mortality outcomes in historically marginalized and vulnerable populations disproportionately affected by the COVID-19 pandemic. To address this need the Rapid Acceleration of Diagnostics for Underserved Popu…

Integrated Research Facility at Fort Detrick

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Connie Schmaljohn · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · 2023 · $42,480,499 — The Integrated Research Facility - Frederick (IRF-Frederick) plays a central role in U.S. Governments high-containment research on emerging infectious diseases. In FY2023, the IRF-Frederick continued support for COVID-19 research and initiated multiple non-COVID-19 research studies. COVID-19 in vi…

Collaborative Research: DMS/NIGMS 1: Identifiability investigation of Multi-scale Models of Infectious Diseases

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Stanca M. Ciupe · VIRGINIA POLYTECHNIC INST AND ST UNIV · 2023 · $183,401 — The emergence and re-emergence of pathogens and their impact on society has reinforced the need for integration and synergy across scientific fields and biological scales in order to advance understanding, predicting, and responding to pathogen spread. Multi-scale mathematical models that consider…

RADx-UP CDCC

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Michael Cohen-Wolkowiez · DUKE UNIVERSITY · 2023 · $12,729,140 — ABSTRACT There is an urgent need to reduce disparities in COVID-19 associated morbidity and mortality outcomes in historically marginalized and vulnerable populations disproportionately affected by the COVID-19 pandemic. To address this need the Rapid Acceleration of Diagnostics for Underserved Popu…

Mechanistic Studies of Gut Dysfunction Exacerbation due to SARS-CoV-2 in HIV/SIV infected Individuals

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

Ivona Vasile Pandrea · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2023 · $397,500 — Abstract With more than 60 million SARS-CoV-2 -infected patients worldwide and nearly 1.5 million COVID-19-related deaths recoreded thus far (November 25), the COVID pandemic is one of the most critical global health problem ever known to humankind, and a major emergency in the US. COVID-19 disprop…

Tulane National Primate Research Center

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

L Lee HAMM · TULANE UNIVERSITY OF LOUISIANA · 2023 · $2,396,052 — Project Summary – Overall The Tulane National Primate Research Center (TNPRC) is affiliated with Tulane University of Louisiana and was dedicated in 1964. The Center is part of Tulane University Health Sciences along with the School of Medicine, the School of Public Health and Tropical Medicine, and…

25th International Workshop on Long-term Complications of HIV and SARS-CoV-2

NIH Pandemic-Era Grants · Pandemic Era Grants / 2023

TODD T BROWN · JOHNS HOPKINS UNIVERSITY · 2023 · $68,333 — With the success of antiretroviral therapy (ART), comorbid diseases are now the leading causes of death and disability in people living with HIV around the globe, including in low- and middle- income countries (LMIC). Large meetings are important venues for scientific exchange regarding the latest a…