Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
SHAUN GRANNIS · REGENSTRIEF INSTITUTE, INC. · 2024 · $3,237,500 — National COVID-19 Cohort Collaborative (N3C): The N3C Data Enclave is a secure platform storing harmonized clinical data provided by more than 50 contributing members. The Enclave hosts over 651 million clinical observations on over 6.5 million persons, including over 2.1 million COVID cases, amount…
ANSHU SHRESTHA · PUBLIC HEALTH INSTITUTE · 2024 · $244,943 — The National Cancer Institute (NCI) Patterns of Care (POC) studies describe, characterize, and compare practice patterns and treatments provided for cancer in different geographic areas of the United States. POC Studies are conducted periodically, typically annually, to satisfy a congressional direc…
lynn briscoe · LEIDOS BIOMEDICAL RESEARCH, INC. · 2024 · $420,000 — The following support shall be provided for Therapeutic Development Branch: • Continuation of the "Integrated Data Resource for Rare Diseases" working with Advanced Biomedical Computational Science at Leidos Biomedical Research, Inc.; • Assay validation and non-GMP and GMP manufacturing of batches o…
GARY MAYS · AXLE INFORMATICS, LLC · 2024 · $3,152,339 — National COVID-19 Cohort Collaborative (N3C): The National COVID-19 Cohort Collaborative (N3C) sponsors the NIH COVID-19 Data Enclave, one of the largest data enclaves in the world supporting COVID-19 research. N3C is a partnership among the NCATS-supported Clinical and Translational Science Awards …
GARY MAYS · AXLE INFORMATICS, LLC · 2024 · $10,367,151 — National COVID-19 Cohort Collaborative (N3C): The National COVID-19 Cohort Collaborative (N3C) sponsors the NIH COVID-19 Data Enclave, one of the largest data enclaves in the world supporting COVID-19 research. N3C is a partnership among the NCATS-supported Clinical and Translational Science Awards …
GARY MAYS · AXLE INFORMATICS, LLC · 2024 · $1,825,925 — National COVID-19 Cohort Collaborative (N3C): The National COVID-19 Cohort Collaborative (N3C) sponsors the NIH COVID-19 Data Enclave, one of the largest data enclaves in the world supporting COVID-19 research. N3C is a partnership among the NCATS-supported Clinical and Translational Science Awards …
Adolfo Garcia-Sastre · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2024 · $702,405 — PROJECT 2: Ex Vivo Analysis of Coronavirus Tropism, Adaptation, Replication, and Host Response In this proposal, we hypothesize that multiple and discrete virus-host interactions and host responses to infection dictate the pathogenic outcome and host tropism of SARS-CoV-2. We further hypothesize th…
Monica Kraft · UNIVERSITY OF ARIZONA · 2024 · $798,118 — This U19 Asthma and Allergic Diseases Cooperative Research Center (AACDRC) Program brings together a team of investigators in three interactive projects and two cores to focus on the pathobiology of specific innate immune mechanisms in viral infection and asthma. In the renewal of our AADCRC program…
Neil King · UNIVERSITY OF WASHINGTON · 2024 · $4,642,108 — PROJECT SUMMARY – PROJECT 4: PROTEIN NANOPARTICLE VACCINES Project 4 focuses on developing generalizable approaches to the design, production, and evaluation of two-component protein nanoparticle vaccines for arenaviruses, phenuiviruses, and paramyxoviruses. These approaches will be enabled by power…
Jianrong Li · OHIO STATE UNIVERSITY · 2024 · $376,173 — Biological Reagents and Infection Core Core 3 - ABSTRACT The overall goals of this Program Project Grant (P01) are to define the functional and molecular roles of caspase- 4/11 (CASP4/11) and RNA epigenetic modifications in SARS-CoV-2 pathobiology in the lung, brain, blood, and heart, to characteriz…
Li Liang · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $7,511,446 — Project Summary/Abstract - Project 1: Adjuvanted Protein Vaccines for Pandemic Preparedness In preparation for possible future pandemics, our goals for Project 1 are to characterize immune responses and to develop new adjuvanted multivalent recombinant protein vaccines that are cross-protective with…
Norbert Pardi · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $3,953,703 — Project Summary/Abstract – Project 2: mRNA Vaccine Development against Bunyaviruses, Paramyxoviruses and Picornaviruses As the emergence of new pathogenic outbreaks in the future is not a matter of “if”, but of “when”, development of prophylactic vaccines against viruses with high pandemic potential…
Jason Scott McLellan · WASHINGTON UNIVERSITY · 2024 · $4,043,107 — PROJECT SUMMARY - Core C: Structure Core Structure-based vaccine antigen design is a key component of the prototype pathogen approach to pandemic preparedness. For each prototype pathogen, vaccine developers must choose which viral protein(s) to include in the vaccine as well as which form of the vi…
Ali Hassan Ellebedy · WASHINGTON UNIVERSITY · 2024 · $5,212,836 — ABSTRACT Core D: Antibody Core Washington University (Ellebedy, Ali) Respiroviruses, Rubulaviruses, Peribunyaviruses, and Phenuiviruses present major health burdens and have pandemic potential. There are no preventative or therapeutic measures against most of the viruses in these families. Infection…
Sharon M Moe · INDIANA UNIVERSITY INDIANAPOLIS · 2024 · $183,572 — The Indiana Center for Musculoskeletal Health (ICMH) Clinical Research Center (ICMH-CRC) will serve as the cornerstone for clinical research conducted in the ICMH. The mission of the ICMH-CRC is to promote and advance clinical research in musculoskeletal (MSK) disorders leading to prevention, diagno…
CAROL D. RYFF · UNIVERSITY OF WISCONSIN-MADISON · 2024 · $249,862 — ABSTRACT – STATISTICS CORE The Core’s overarching goal is to provide methodological and statistical support for all research projects in the U19 and Adjunct AD/ADRD U01, and facilitate the use of the rich MIDUS longitudinal data to the fullest extent possible by investigators. Core activities encour…
David E Lanfear · WAYNE STATE UNIVERSITY · 2024 · $310,406 — Abstract Heart failure (HF) is one of the most common, costly, and deadly diseases affecting humans. Hypertension is the largest single risk factor for HF, accounting for over half of all new cases. Moreover, Black adults with hypertension have a much greater risk, perhaps 20-fold, of developing …
Jaymia Ann Mitchell · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2024 · $150,948 — COMMUNITY LIAISON AND RECRUITMENT CORE (CLRC) ABSTRACT African American older adults continue to lag dramatically behind Non-Hispanic Whites in terms of both health outcomes and participation in health research. The most common barriers to research recruitment are fear and mistrust. The Healthier Bl…
HEATHER KIRKORIAN · GEORGETOWN UNIVERSITY · 2024 · $142,773 — PROJECT SUMMARY/ABSTRACT Parents’ mental health predicts their young children’s media use. Yet, research often ignores the family context in which media are used, overlooking the influence of parents as gatekeepers of their children’s digital media exposure. To address the gap in understanding the …
Reno L Charette · AMERICAN INDIAN HIGHER EDUCATION CONSRTM · 2024 · $495,553 — AIHEC BIRCH Overall Core Project/Narrative The vision of the American Indian Higher Education Consortium’s (AIHEC) “Building Indigenous Research Capacity in Health” (BIRCH) project is sovereign Tribal Nations asserting full ownership, direction, and control of the health research needed to help thei…