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9873 documents

Leveraging SNAP to Improve Mental Health Outcomes: Evidence from the COVID-19 Emergency Response

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Chima Ndumele · YALE UNIVERSITY · 2024 · $557,800 — Project Summary Social determinants, including those related to food and housing, have a powerful impact on health, but there is uncertainty on how to best leverage policy to improve individuals’ social circumstances and related health outcomes. Presently, 11% of Americans have food insecurity, incl…

Temporal Phenotypes and Risk Models for the Post-COVID Syndrome and its sub-types

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Hossein Estiri · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $818,071 — Project Summary/Abstract The fight against the SARS-CoV-2, the coronavirus that causes COVID-19, is ramping up with vaccinations and therapeutics. Yet there is a growing urgency to study and address the other side of the pandemic, a shapeshifting byproduct known as the post-acute sequelae of COVID-1…

BLRD Research Career Scientist Award Application

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Wendy B Bollag · CHARLIE NORWOOD VA MEDICAL CENTER · 2024 — Project Summary/Abstract This application requests the appointment of Dr. Wendy Bollag, a Research Physiologist at the Charlie Norwood VA Medical Center in Augusta, Georgia and a Professor of Physiology at the affiliate institution (Augusta University), to the position of Research Career Scientist.…

Auto-antibodies as predictive markers for Post treatment Lyme Disease Syndrome

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Linden T Hu · TUFTS UNIVERSITY BOSTON · 2024 · $616,612 — ABSTRACT As an organism that persists in its natural hosts for long periods of time, Borrelia burgdorferi, the causative agent of Lyme disease, has adapted many strategies for survival and evasion of host immune responses. It has a very small genome and is unable to produce many essential nutrients …

Using Data Science to Quantify the Impact of Misinformation, Mistrust, and Other Key Psychosocial Factors on Vaccine Hesitancy Among Vulnerable People Experiencing Psychopathology

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Michael V Bronstein · UNIVERSITY OF MINNESOTA · 2024 · $187,261 — People with severe mental illness (SMI) are ~3x more likely to contract and ~7x more likely to die from vaccine- preventable disease. And yet, vaccine uptake is significantly lower among people with SMI, likely due to greater vaccine delay/refusal despite availability (“hesitancy”). Critical knowled…

Expanding Swabseq sequencing technology to enable readiness for emerging pathogens

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Valerie A Arboleda · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $575,226 — This application aims to develop improved methods for detecting novel pathogens that can be deployed on a large scale and are flexible to multiple pathogens. The method uses the power of next generation sequencing technology to analyse hundreds of thousands of samples simultaneously. In contrast to …

K-VAC: Kentucky Vaccinating Appalachian Communities

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Kathryn Marie Cardarelli · UNIVERSITY OF KENTUCKY · 2024 · $607,507 — ABSTRACT Vaccination of adults is central to control of SARS-CoV-2/COVID-19 and multiple other infectious diseases. Failure to engage in vaccine uptake is a complex, multilevel systems problem--individual factors such as fatalism, lack of factual information, medical and government mistrust, and pol…

Home Health, ADRD, Telehealth, and Patient Outcomes

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

DANA B MUKAMEL · UNIVERSITY OF CALIFORNIA-IRVINE · 2024 · $665,894 — PROJECT SUMMARY/ABSTRACT Close to 40% of home health patients have been identified as persons with Alzheimer’s Disease or Related Dementias (ADRD). As the prevalence of ADRD in the population in general is expected to double by 2050, so will the percent of patients with ADRD treated by home health a…

Multidisciplinary Investigations in Visual Science

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Val C. Sheffield · UNIVERSITY OF IOWA · 2024 · $618,000 — PROJECT SUMMARY The goal of this National Eye Institute (NEI) P30 competitive renewal is to continue to enhance the research activities of NEI-funded investigators at The University of Iowa. This will be achieved by providing a suite of Core Services, performed by skilled technical staff and supervi…

The Utah Regional Network for Excellence in Neuroscience Clinical Trials (UR-NEXT)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Joshua Leitch Bonkowsky · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2024 · $410,407 — Multicenter clinical trials face numerous challenges including recruitment, lack of clinical trial expertise, and inefficiencies in IRB approval and contracting. The Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT) has addressed these by organizing 25 research sites and central Dat…

Mitigating effects of telehealth uptake on disparities in maternal care access, quality, outcomes, and expenditures during the COVID-19 pandemic

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Peiyin Hung · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · 2024 · $603,549 — Project Summary The Coronavirus disease 2019 (COVID-19) pandemic has caused significant social, healthcare, and economic devastation in the United States (US), potentially exacerbating the maternal health disparities facing rural women and women of color. Telehealth represents a promising opportunit…

Enteric Pathogen Force of Infection among Children using Serology

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Benjamin F Arnold · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2024 · $724,079 — Enteric pathogen infections are a leading cause of the global disease burden, with the largest burden among children in low-resource settings. Stool-based PCR methods have dramatically improved our ability to measure enteric infections, but the challenge of collecting stool and need for near-continu…

Increasing Peer Support for OUD Recovery during COVID-19 through Digital Health: A National Randomized Controlled Trial

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Francesca Beaudoin · BROWN UNIVERSITY · 2024 · $790,495 — PROJECT SUMMARY Increasing numbers of opioid overdoses have been observed during the COVID-19 pandemic, likely reflecting the pandemic’s multiple effects on this already vulnerable population. People in recovery from opioid use disorder (OUD) have reported disproportionate psychosocial distress and …

Glial activation and metabolite contributions to 'brain fog' post-acute sequelae of COVID-19 (PASC)

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Michael B VanElzakker · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $208,750 — Project summary The COVID-19 pandemic has left potentially millions of individuals with ongoing symptoms months after initial infection by SARS-CoV-2, a syndrome called post-acute sequalae of COVID-19, or PASC. A common and often-debilitating core symptom of PASC is colloquially known as "brain fog,…

Sympathetic-Vascular Dysfunction in Obesity-Related Hypertension

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

SETH WILLIAM HOLWERDA · UNIVERSITY OF KANSAS MEDICAL CENTER · 2024 · $362,678 — PROJECT SUMMARY Obesity is highly prevalent in the U.S. and has significant consequences for mortality and quality of life. Obesity is the primary gateway to additional cardiovascular disease (CVD) risk factors such as increased insulin resistance, dyslipidemia, and hypertension. Prospective studie…

North STAR Trial: Specialty Telemedicine Access for Referrals in Rural Alaska

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Susan Davis Emmett · UNIV OF ARKANSAS FOR MED SCIS · 2024 · $649,512 — ABSTRACT Rural Alaska Native children experience a high prevalence of preventable childhood hearing loss. School-based programs provide the only access to preventive services for many underserved rural and minority children, yet loss to follow-up from school hearing screening is common and scarcity …

CODA: COvid and Diabetes Assessment

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Jason Perry Block · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $7,977,662 — Project Summary Several studies have found that infection with SARS-CoV-2 and COVID-19 diagnosis are associated with the development and progression of both Type 1 (T1D) and Type 2 Diabetes (T2D), possibly through infection of beta cells, increased insulin resistance, increased inflammation and fibr…

Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment for Opioid Use Disorder

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Nina Cooperman · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $669,776 — PROJECT SUMMARY The United States is experiencing an opioid use and overdose crisis. To address this crisis, programs that provide medication for opioid use disorder (MOUD) are being expanded and enhanced. MOUD is the most effective intervention for an OUD, and methadone treatment (MT) is the most …

Effects of Early and Prolonged Parent-Child Separation: Understanding Mental Health among Separated-Reunited Chinese American Children

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Shaobing Su · UNIV OF MASSACHUSETTS MED SCH WORCESTER · 2024 · $248,329 — PROJECT SUMMARY/ABSTRACT The goal of this K99/R00 proposal is to facilitate Dr. Shaobing Su's transition into the role of independent investigator focused on understanding how early and prolonged parent-child separation (i.e., separated at ages 0-6 for at least 6 months per year) shapes the mental …

Multi-level evidence-based intervention to reduce health and education disparities among children of color in high-poverty schools in historically disinvested neighborhoods hardest hit by the pandemic

NIH Pandemic-Era Grants · Pandemic Era Grants / 2024

Laurie Miller Brotman · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2024 · $716,351 — PROJECT SUMMARY/ABSTRACT This study evaluates the enduring protective impacts of a multi-level evidence-based intervention, ParentCorps, in high-poverty schools with pre-Kindergarten (pre-K) programs serving primarily Black and Latino children in New York City (NYC) neighborhoods hit hard by the COV…