Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
INDRA N SARKAR · AMERICAN MEDICAL INFORMATICS ASSN · 2024 · $20,000 — Project Summary The field of biomedical informatics continues to face an urgent need to expand the pipeline of talented students to meet the increased demand for biomedical informatics and health data science expertise and to improve diversity in the field. Nationally, there is increased awareness o…
JACQUELINE MARGO BROOKS CARTHON · UNIVERSITY OF PENNSYLVANIA · 2024 · $495,067 — This is a continuation application for years 26 through 30 of the Advanced Training in Nursing Outcomes Research (T32NR007104) pre- and post-doctoral training program, funded by NINR. Over its lifetime, our T32 program has trained 32 PhDs and 43 postdoctoral trainees who are now doing research in mo…
MIGUEL S ESTEVES · NORTHWESTERN UNIVERSITY · 2024 · $548,624 — Abstract: Real-Time Tracking of Gene Therapy by Bioactivated MR contrast Probes With mean survival rate of 5 years (and most cases are fatal) lysomal storage diseases (LSD) are among the most dismal of prognosis in all of medicine. LSD's represent a large number of monogenetic diseases and while ra…
Kamrul M Hasan · CHARLES R. DREW UNIVERSITY OF MED & SCI · 2024 · $144,500 — Project Summary: With the dramatic increase in obesity and diabetes, the prevalence of nonalcoholic fatty liver diseases (NAFLD) is increasing at an alarming rate worldwide. NAFLD is a significant risk factor for insulin resistance (IR), type 2 diabetes (T2DM), and cardiovascular diseases. We need t…
Bhavana Patel · UNIVERSITY OF FLORIDA · 2024 · $138,960 — Project Summary/Abstract Lewy body dementia (LBD) is the second most common neurodegenerative dementia in the United States and one of the Alzheimer’s disease-related dementias (ADRDs). It affects 1.4 million Americans and their caregivers. Individuals with LBD are affected by both physical and cogn…
Leslie J Crofford · VANDERBILT UNIVERSITY · 2024 · $348,873 — PROJECT SUMMARY This renewal application seeks continued support for the T-32, Interdisciplinary Training in Rheumatic Diseases at Vanderbilt University. The program seeks support for 2 predoctoral and 3 postdoctoral positions. The goal of the program is to provide the next generation of investigato…
Timothy William Dunn · DUKE UNIVERSITY · 2024 · $584,488 — Scope of Work Duke will complete all work for the machine learning model building and implementation of the model into the Duke clinical workflow. For Aim 1 of the project, this work will include data extraction and cleaning, neural network architecture design, and model optimization and validation.…
Gary Thomas · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $564,186 — Project Summary PACS2 syndrome is a recently identified neurodevelopmental disorder caused by a recurrent de novo missense mutation in PACS2 (p.Glu209Lys (PACS2E209K)). Patients carrying this missense mutation suffer from developmental and epileptic encephalopathy-66 (DEE66), and share several defic…
Rosalie Griffin · MAYO CLINIC ROCHESTER · 2024 · $245,120 — ABSTRACT Monoclonal B-cell lymphocytosis (MBL) is a precancerous state affecting 8-10 million adults with no existing cancer control strategies. As a precursor to chronic lymphocytic leukemia (CLL), MBL is characterized by the presence of monoclonal B-cell clones in the peripheral blood of otherwis…
Scott Alan Smith · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $763,421 — PROJECT SUMMARY There is a growing body of evidence that the allergic immune response is directed toward ectoparasites, like it is helminths (endoparasites), possibly playing a central role in the phenomenon known as acquired tick resistance. We hypothesize that human immunity naturally develops fol…
Victor J. Thannickal · TULANE UNIVERSITY OF LOUISIANA · 2024 · $609,272 — PROJECT SUMMARY Cell metabolism regulates epigenetic reprograming to determine cellular identity and fate. Intermediary metabolites serve as essential cofactors for epigenetic modifying enzymes. Epithelial- mesenchymal crosstalk is critical for the maintenance of adult tissues/organs and in regener…
Margaret Taylor Davis · YALE UNIVERSITY · 2024 · $798,272 — PROJECT SUMMARY The goal of this study is to investigate the role of the kappa opioid receptor (KOR) in the symptomatology of borderline personality disorder (BPD), a condition associated with alarmingly elevated risk for suicide attempt (SA; up to 75%) and death by suicide (up to 10%). Despite BPD…
Kim Tran · DES MOINES UNIV OSTEOPATHIC MEDICAL CTR · 2024 · $453,404 — PROJECT SUMMARY Reduced nitric oxide (NO) availability is a common pathophysiological feature of many cardiovascular diseases. While NO donors are used, significant issues limit their utility, including the development of nitrate tolerance and endothelial dysfunction. Although intermittent nitrate …
Gulchekhra Pirova · UNIVERSITY OF ILLINOIS AT CHICAGO · 2024 · $227,031 — Abstract This R34 application responds to RFA-MH-23-260 by adapting and piloting a novel intervention for suicide prevention in primary care for women at moderate or high risk for suicide in a low- and middle income countries. The study takes place in Tajikistan, a postwar country in Central Asia, w…
Seth Tichenor · DUQUESNE UNIVERSITY · 2024 · $390,959 — PROJECT SUMMARY The term adverse impact refers to the negative personal reactions, broader speech- or communication-related consequences, and overall life challenges that adults who stutter may experience as a result of their speaking difficulties. Though the risk of broader life impact is widely ac…
Summer Braun · UNIVERSITY OF ALABAMA IN TUSCALOOSA · 2024 · $455,477 — PROJECT SUMMARY/ABSTRACT Mental health concerns in teachers have escalated since the onset of the pandemic, and the deterioration of mental health can begin as early as the teacher training period. Accessible and scalable programs that prepare teachers for the stress of the profession are urgently …
Jennifer Leslie Fish · UNIVERSITY OF MASSACHUSETTS LOWELL · 2024 · $455,939 — PROJECT SUMMARY Craniofacial malformations are among the most common human birth defects. Tissues of the head and neck derive from the pharyngeal arches (PAs). PAs are transient developmental structures formed by mesenchymal populations, the neural crest (NC) and mesoderm, that migrate in between ep…
Christy Michelle McKinney · UNIVERSITY OF WASHINGTON · 2024 · $194,400 — The proposed NIH KL2 INCLUDE Career Development Award supports a promising dual-degree (DDS, PhD) early career faculty to train in the clinical and translational research to improve and extend the oral healthspan in people with Down syndrome (DS). With a higher prevalence of oral inflammatory diseas…
KATHRYN M ROEDER · CARNEGIE-MELLON UNIVERSITY · 2024 · $592,551 — Project summary/abstract In this application, we request continuation of MH123184, which aimed to understand how genetic variation alters transcription in specific cells and thereby produces psychopathology. Our research developed statistical methods to integrate single cell and tissue-level transcr…
Keri Elizabeth Lunsford · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $748,049 — PROJECT SUMMARY Due to organ shortage, livers are transplanted in order of recipient medical urgency; however, ethical principles dictate avoidance of futile transplantation. The most common cause of death early after liver transplant (i.e. futility) relates to consequences of an immune system which…