Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
DEBABRATA MUKHOPADHYAY · MAYO CLINIC JACKSONVILLE · 2024 · $667,504 — Project Summary The long-term objective of this application is to understand the molecular pathways of myocardial infraction (MI)- mediated cardiac fibrosis and eventually heart failure. In our last grant cycle, we elucidated thoroughly the role of Neuropilin-1 (NRP1), a multi-ligand receptor/adapto…
Kirsty Donald · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $521,003 — Maternal substance use disorders are a substantial public health concern and the neurological consequences of prenatal exposure are a major threat to the long-term health of offspring. Globally, prevalence of Fetal Alcohol Syndrome (FAS) and Fetal Alcohol Spectrum Disorders (FASD) is between 2-7 and…
IRENE S DAVIS · UNIVERSITY OF SOUTH FLORIDA · 2024 · $497,235 — Plantar fasciitis, a repetitive strain injury, is one of the most common causes of foot pain. Ten percent of aging adults experience plantar fasciitis with 50% of the cases being disabling. Foot pain can lead to other problems such as reduced mobility, depression and prescription medication use, lea…
Shannon Delia Glenn · PENNSYLVANIA STATE UNIVERSITY, THE · 2024 · $48,974 — ABSTRACT College drinking continues to be a major public health concern in the United States and a priority area within NIAAA. About 1 in 3 students report heavy episodic drinking (HED; 4+/5+ females/males) and 1 in 10 engage in high-intensity drinking (HID; 8+/10+ females/males). Students who engag…
Fiona Horner · CARNEGIE-MELLON UNIVERSITY · 2024 · $42,574 — PROJECT SUMMARY/ABSTRACT Type 1 diabetes is an exceptionally challenging disease to manage, requiring a host of complex behaviors to manually regulate one’s blood glucose. Importantly, these disease management behaviors must be responsive to the ever-changing needs of one’s day-to-day environment; t…
Sabrina Todaro · UNIVERSITY OF RHODE ISLAND · 2024 · $48,974 — Project Summary/Abstract Simultaneous use of alcohol and cannabis, or co-use (i.e., the use of both substances so that effects overlap), is an increasingly significant public health concern among young adults between the ages of 18 and 25 in the U.S. Compared to single substance use occasions of alc…
Charles Heckman · NORTHWESTERN UNIVERSITY AT CHICAGO · 2024 · $388,000 — Summary/Abstract All motor commands flow through motoneurons (MNs), which are probably the most thoroughly studied of all spinal neurons. Perhaps the most striking result to emerge from the many studies of MNs is that neuromodulatory input from the brainstem exerts an enormous impact on motoneuron e…
Anna Shafer-Skelton · UNIVERSITY OF PENNSYLVANIA · 2024 · $74,284 — PROJECT SUMMARY/ABSTRACT Spatial neuroscience has uncovered a great deal about how animals—primarily rodents—form allocentric (world-centered) spatial maps of the world. Rodents explore by moving their bodies through the world. In contrast, primates explore the world visually, and recent work sugge…
Alex Yashchenko · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2024 · $37,439 — PROJECT SUMMARY/ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is the most commonly inherited kidney disease in the world. It is characterized by large fluid-filled cysts that disrupt kidney function, eventually leading to end stage kidney disease. Previous literature indicates that k…
Stephanie Roslyn-Isabelle Chung · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $37,329 — PROJECT SUMMARY/ ABSTRACT Family planning prevents unwanted pregnancy and reduces maternal and child mortality in low-resourced settings; however, women in these settings encounter unnecessary medical barriers to contraceptive care. Inappropriate medical contraindications (IMCs) occur when providers…
Moses O Oyewumi · NORTHEAST OHIO MEDICAL UNIVERSITY · 2024 · $406,394 — Summary The use of autogenous bone graft is the most common clinical approach for bone regeneration. Although, the practice has resulted in high rates of fusion success, there are challenges with increased operative time, limited availability of autologous bone, blood loss and donor-site morbidity. …
MATTI HAMALAINEN · AALTO UNIVERSITY · 2024 · $507,643 — Project Summary During the past three decades non-invasive functional brain imaging has developed immensely in terms of measurement technologies, analysis methods, and innovative paradigms to capture information about brain function both in healthy and diseased individuals. While functional MRI (fMR…
Hannah LF Cooper · EMORY UNIVERSITY · 2024 · $704,248 — Abstract: People who use drugs (PWUD) and are pregnant or postpartum are trying to survive at the intersection of 2 of the gravest public health crises confronting the 21st century US: epidemics of (1) drug-related harms, and (2) maternal morbidity and mortality. The US has the highest rate of mater…
KAREN L. MOHLKE · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $638,741 — Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text. Genome-wide association studies (GWAS) have successfully identified thousands of genetic signals associated with common, complex diseases and quantitative traits. How…
Christopher Lee Pulliam · CASE WESTERN RESERVE UNIVERSITY · 2024 · $24,724 — PROJECT SUMMARY The journey from health research to patient-centered solutions, especially in the realm of neural engineering and neurotechnology, presents numerous challenges. These span from the intricacies of clinical requirements to the complexities of regulatory landscapes. Moreover, traditiona…
Greta Bushnell · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · 2024 · $58,998 — PROJECT SUMMARY/ABSTRACT. This Mentored Research Scientist Development Award (K01) proposal will develop Dr. Greta Bushnell’s career as an independent investigator, and enable her to advance into a new line of research focused on evaluating misuse and abuse related morbidity of medicines prescribed …
Evan Plys · MASSACHUSETTS GENERAL HOSPITAL · 2024 · $193,637 — The timing of a skilled nursing facility (SNF) stay is met with significant psychological stress for both patients and family care-partners (CPs), which can negatively impact recovery as well as long-term health and psychological outcomes. These consequences may be magnified among socioeconomically …
Mary Catherine Andorfer · MICHIGAN STATE UNIVERSITY · 2024 · $284,903 — PROJECT SUMMARY Glycyl radical enzymes (GREs) are a growing superfamily that catalyzes an impressive array of chemical transformations critical to both human health and the environment. GREs share a common glycyl radical cofactor which allows them to perform challenging, otherwise inaccessible chemi…
Arum Han · UNIVERSITY OF TEXAS MED BR GALVESTON · 2024 · $234,053 — ABSTRACT Spontaneous preterm birth (PTB) affects approximately 11% of all births and is a significant contributor to neonatal mortalities and morbidities. Current interventions in PTB are designed to stop maternal uterine contractions to delay delivery but have limited success. Infection and host in…
Xiangming Ji · EPIC NUTRITION FOR Y LLC · 2024 · $194,275 — PROJECT SUMMARY/ABSTRACT: Obesity is a major public health problem in the United States. It is linked to insulin resistance and type 2 diabetes, two devastating diseases that affect millions of Americans. Current treatments for obesity have largely failed to achieve long-term success, highlighting t…