Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Emad M Boctor · JOHNS HOPKINS UNIVERSITY · 2024 · $377,461 — Project Summary Vascular access is the most common medical procedure in the world, with over a billion insertions performed annually. In the United States, over 350-million peripheral intravenous (IV) catheters are sold yearly, in addition to millions of central and arterial lines. However, peripher…
Gregory Patrick Davis · WEILL MEDICAL COLL OF CORNELL UNIV · 2024 · $79,284 — PROJECT SUMMARY / ABSTRACT Persistent activity in neural circuits supports a variety of brain functions from motor control to navigation to perceptual decision-making. Correlational studies show significant variation in persistent activity patterns during different behaviors, suggesting that individ…
Nicholas W Simon · UNIVERSITY OF MEMPHIS · 2024 · $173,417 — Abstract A fundamental characteristic of substance use disorder (SUD) is ongoing drug seeking and misuse despite physical, financial, and legal consequences. Critically, aversive consequences following a substantial delay, such as withdrawal after substance use, are often underestimated. Despite the…
Christine Elissa Eyler · DUKE UNIVERSITY · 2024 · $239,693 — PROJECT SUMMARY/ABSTRACT Locally advanced rectal cancer, defined by spread to lymph nodes or extension through the full rectal wall thickness, is diagnosed in over 15,000 US patients yearly. Standard treatment for locally advanced rectal cancer in the US involves chemotherapy and radiation therapy (…
Anisha Babu · UNIVERSITY OF OREGON · 2024 · $48,735 — PROJECT SUMMARY The hippocampus plays an essential role in encoding long-term episodic memories. However, because many of the experiences we encode share similar features (people, locations, objects), a critical challenge for the episodic memory system is to prevent interference or confusion between…
Daniel W McNeil · UNIVERSITY OF FLORIDA · 2024 · $733,029 — Project Summary/Abstract The University of Florida (UF) College of Dentistry and East Carolina University (ECU) School of Dental Medicine are collaborating to establish an academic multidisciplinary practice-based research network within and between their respective dental schools to provide clinic…
ANAEZE C OFFODILE · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $494,244 — Project Summary/Abstract In 2014, the state of Maryland, under a federal waiver, enacted an all-payer Global Budget Revenue (GBR) model that prospectively set limits on hospital revenue. It also required the state to limit growth in per-capita spending and mandated reductions in preventable complic…
Lamia Haque · YALE UNIVERSITY · 2024 · $194,267 — ABSTRACT Deaths due to alcohol-associated liver disease (ALD), a serious consequence of alcohol use disorder (AUD), have risen substantially over the past two decades. Although reduction and cessation of alcohol use is a vital component of treating ALD, few patients with AUD and ALD receive treatmen…
Amy Monasterio · BOSTON UNIVERSITY MEDICAL CAMPUS · 2024 · $48,694 — PROJECT SUMMARY/ABSTRACT Defining how we form, store, and retrieve memories is one of neuroscience’s most researched areas. The hippocampus is a well-characterized forebrain structure with a crucial role in the formation and retrieval of episodic memory, and is known to be vulnerable to age-related …
Kathleen R Chirco · OREGON HEALTH & SCIENCE UNIVERSITY · 2024 · $248,998 — As the leading cause of inherited retinal degeneration, retinitis pigmentosa (RP) affects about 1.5 million people worldwide. Bardet-Biedl syndrome (BBS) is the second most common causes of syndromic RP, and is characterized as an autosomal recessive ciliopathy with severe photoreceptor degeneration…
Todd Schoenbaum · AUGUSTA UNIVERSITY · 2024 · $147,251 — Project Abstract Training in Clinical Dental Research is fundamental to the progress of the profession and patient care. Current opportunities in US dental schools are limited. Our proposal will recruit and train the next generation of Dental Clinician-Scientists. Our project will create a new 2-yea…
Christopher D. Houck · KLEIN BUENDEL, INC. · 2024 · $938,856 — Internet-based TRAC (i-TRAC): Interactive Emotion Regulation Skills Training to Improve Adolescent Sexual Health Adolescence is a critical developmental period during which behavioral patterns are formed that have powerful influences on current and future health. This is particularly true for sexua…
Marisol Tellez Merchan · TEMPLE UNIV OF THE COMMONWEALTH · 2024 · $710,819 — SUMMARY The Collaborative ICPRS clinically-oriented predoctoral/postdoctoral administered development current proposal titled “Sequential Modeling for Prediction of Periodontal Disea ses: An I ntra- Practice-Based Research Study ( ICPRS)” is developed in response to RFA-DE-23-012 . The will seek t…
WILLIAM C BECKER · VA CONNECTICUT HEALTHCARE SYSTEM · 2024 — The intersecting problems of high-impact chronic pain and the opioid overdose crisis continue to be major public health concerns because of prevalence, costs, disparities, and societal burden, yet very few solutions to support comorbid chronic pain, opioid dependence, and opioid-related harms are av…
THERESA E HAHN · ROSWELL PARK CANCER INSTITUTE CORP · 2024 · $735,428 — ABSTRACT Immune checkpoint inhibitors (ICIs) have markedly transformed the therapeutic landscape for many types of advanced malignancies over the past decade. A sizable proportion of patients with advanced cancer derive durable benefits from ICIs and achieve longer periods of progression-free surviv…
JOSHUA A SONNEN · TUFTS UNIVERSITY MEDFORD · 2024 · $594,130 — Project Summary 1) Objectives: We will define associations and pathways through which exposure to PM2.5 and metals contribute to dementia-associated neuropathology (DAN), incident dementia, and cognitive function. We will do so by leveraging resources from the Adult Changes in Thought (ACT) study, a…
Anna Michael Gorczyca · UNIVERSITY OF KANSAS MEDICAL CENTER · 2024 · $637,649 — PROJECT SUMMARY Diabetes disproportionately impacts the 60 million individuals living in rural areas where the prevalence of Type 2 diabetes (T2D) is ~17% higher than in urban areas. The Centers for Disease Control and Prevention’s (CDC) National Diabetes Prevention Program (NDPP) which includes a m…
Tejabhiram Yadavalli · UNIVERSITY OF ILLINOIS AT CHICAGO · 2024 · $398,369 — Ocular inflammatory diseases are the primary cause of blindness in the USA. While emergence of ocular inflammation can be genetic or idiopathic, pathogens such as bacteria, fungi and viruses that infect the eye are primary causes. Microbial infections are treated with antimicrobials followed by anti…
Diane Bimczok · MONTANA STATE UNIVERSITY - BOZEMAN · 2024 · $325,205 — SUMMARY Minority graduates are significantly underrepresented in biomedical PhD programs nationwide. Montana State University (MSU), a research-intensive public land-grant university, serves a significant number of first- generation rural and low-income students who rarely enroll in PhD programs. L…
RANDY PATRICK AUERBACH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2024 · $964,336 — Project Summary Over the past 15 years, suicide rates among adolescents have increased ~60%. Recently, problematic social media use has been linked to the emergence of suicidal thoughts and behaviors (STB), perhaps reflecting greater interpersonal stress exposure. Understanding the type, timing, an…