Pandemic-era NIH grants (FY2019-2024) covering coronavirus, gain-of-function research, mRNA vaccines, biosafety, and related funding flows. Metadata + abstracts from NIH RePORTER.
Get an AI answer drawn only from the NIH Pandemic-Era Grants documents indexed here — every claim cited back to the filing or proceeding it came from. It will tell you plainly when the record doesn't cover your question, rather than guessing.
Wei Ji Ma · NEW YORK UNIVERSITY · 2024 · $326,116 — PROGRAM SUMMARY The Training Program in Computational Neuroscience (TPCN) will support integrated undergraduate and graduate training in computational neuroscience at New York University. The program will be hosted by the Center for Neural Science (CNS) and the Cognition and Perception (C&P) program…
Abigail S. Friedman · YALE UNIVERSITY · 2024 · $521,709 — PROJECT SUMMARY The past 20 years have seen significant changes in the US’s legal cannabis landscape alongside marked changes in tobacco use, the leading cause of preventable mortality. Yet recreational cannabis legalization’s (RCL’s) effects on tobacco product use remain unclear: few peer-reviewed …
Daniel Berry · MAYO CLINIC ROCHESTER · 2024 · $647,503 — ABSTRACT - OVERALL Total joint arthroplasty (TJA) is the most common and fastest growing surgery in the nation with more than 7 million Americans currently living with artificial joints. Despite the high surgery volume, the evidence base for TJA procedures, technologies and associated interventions …
Kimberly Elizabeth Beatty · OREGON HEALTH & SCIENCE UNIVERSITY · 2024 · $385,000 — Abstract The Beatty group's research program is investigating how cellular proteins organize and interact in space and time. We use the principles of chemical biology to create new technologies for labeling and imaging proteins with an innovative set of reporters. Recent advances in imaging instru…
Gabrelle Lavender Hackman · UNIVERSITY OF TEXAS AT AUSTIN · 2024 · $39,539 — PROJECT SUMMARY Broad Impact: Prostate cancer (PCa) is the most commonly diagnosed cancer in American men and in 2022 alone will result in the death of over 34,000 men. PCa mortality is typically caused by disease that has advanced to the metastatic castration-resistant stage (mCRPC) and has spread …
Louise Mewton · UNIVERSITY OF SYDNEY · 2024 · $239,452 — PROJECT SUMMARY/ABSTRACT Globally, 1.34 billion people consume alcohol in harmful amounts, with alcohol use accounting for 1.78 million deaths in 2020. Alcohol use often begins, and noticeably escalates, throughout adolescence. Incidence of alcohol use disorder (AUD) and related symptomatology follo…
Rebecca Ashare · STATE UNIVERSITY OF NEW YORK AT BUFFALO · 2024 · $599,442 — Project Abstract Up to 40% of patients report using cannabis for symptom management during and after cancer treatments despite gaps in our understanding of its longitudinal therapeutic uses and harms. Simultaneously, immuno- oncology is a rapidly advancing field of cancer treatment. Nearly 44% of ca…
William Dylan Hale · JOHNS HOPKINS UNIVERSITY · 2024 · $102,973 — PROJECT SUMMARY AMPA-type glutamate receptors (AMPARs) are the major excitatory neurotransmitter receptors in the brain and changes in AMPAR number at synapses underlie learning and memory as well as human disease. A detailed understanding of how AMPARs are organized at synapses is critical to unde…
Karen SACHS · MODULO BIO, INC. · 2024 · $1,428,644 — Project Summary/Abstract: ALS and FTD are fatal neurodegenerative diseases that presently have no cure. To date, one focus area in ALS research has been developing model systems to characterize the condition, with over 20 different ALS mouse models, and more recently, numerous iPSC based models, eac…
Taneisha Gillyard Cheairs · MEHARRY MEDICAL COLLEGE · 2024 · $363,750 — Project Summary/ Abstract The goal of the STrengthening Research OpportuNities for Growth at Meharry Medical College (Meharry- STRONG) Program is to assess research capacity and develop an institution-wide action plan to meet our specific needs identified. We hypothesize that first developing an inf…
Baltazar Chilundo · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $304,377 — PROJECT ABSTRACT Mozambique has made considerable strides in its national HIV response, specifically in its progress towards the lofty UNAIDS 95-95-95 goals. Yet, despite this progress, significant gaps persist, including numerous incident infections, large numbers of persons living with HIV (PLWH) …
Havell Markus · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · 2024 · $34,800 — PROJECT SUMMARY/ABSTRACT The human X chromosome has long been hypothesized to play a significant role in the etiology of sex-biased diseases and traits, particularly autoimmune diseases like lupus. Despite its importance, the X chromosome is largely understudied in genetic association and functional…
Allan Guymon · UNIVERSITY OF IOWA · 2024 · $581,274 — Project Summary Cochlear implant (CI) electrode arrays are made of platinum wires and contacts encased in a silastic housing. These materials provide mechanical stability and flexibility critical to the long-term function of the CI. However, they also induce local tissue reactions that can have detr…
Wolfgang Beckabir · UNIV OF NORTH CAROLINA CHAPEL HILL · 2024 · $53,974 — Project Summary/Abstract Bladder cancer is a prevalent and deadly cancer, with over 80,000 new cases and 17,000 deaths annually in the United States. Advanced bladder cancer has only a 15% 5-year survival rate. One of the most effective treatments for advanced bladder cancer is immune checkpoint blo…
Frank G. Ondrey · UNIVERSITY OF MINNESOTA · 2024 · $103,823 — Project Summary/Abstract With stagnant cure rates, there is a severe unmet need for strategies to improve oral and all other types of aerodigestive cancer survival. There are no robust chemoprevention drugs or other treatments for high risk oral precancerous conditions or field carcinogenesis despit…
Karen Woo · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2024 · $314,566 — Project Summary/Abstract Patients with end-stage kidney disease (ESKD), who use hemodialysis as their kidney replacement method, require vascular access in the form of an arteriovenous fistula, arteriovenous graft, or central venous catheter to receive life-sustaining hemodialysis. Providers and pat…
ANDREY ZINCHUK · YALE UNIVERSITY · 2024 · $172,260 — Candidate. My goal is to become an independent physician-scientist who merges physiology and patient-ori- ented research methods to personalize care for patients with obstructive sleep apnea (OSA). My training as an engineer and a doctor in Pulmonary, Critical Care and Sleep Medicine (PCCSM), comple…
Paul L. Auer · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 · $703,426 — Project Summary With age, dividing cells acquire DNA mutations. A small number of these somatic mutations confer a selective advantage leading to a clonal proliferation of cells harboring the somatic mutation. In blood, this process is termed ‘clonal hematopoiesis’. These mutations include both poin…
Benjamin Greenbaum · SLOAN-KETTERING INST CAN RESEARCH · 2024 · $617,031 — PROJECT SUMMARY Transcriptional dysregulation in tumors can induce the abundant expression of repetitive elements in cancerous cells compared to normal tissues, where they are often transcriptionally silent. Such transcripts have been associated with better outcomes to cancer immunotherapies, as the…
YONG XU · BAYLOR COLLEGE OF MEDICINE · 2024 · $601,556 — PROJECT SUMMARY Regular physical activity is a powerful intervention that reduces obesity and confers protection against obesity-associated metabolic diseases. The mechanisms responsible are incompletely understood but are likely to extend beyond activity-associated increases in energy expenditure a…