NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2021 · $3,008,705 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
TIMOTHY STEDMAN · AMERICAN TYPE CULTURE COLLECTION · 2021 · $171,926 — This contract provides unique and quality-assured infectious reagents and resources to the scientific community for use in basic research and product development. The scope of this contract includes the acquisition, authentication, production, preservation, storage, and distribution of research and …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
PETER MYLER · SEATTLE CHILDREN'S HOSPITAL · 2021 · $410,584 — The goal of the Structural Genomics Centers for Infectious Diseases is to apply state-of-the-art, high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins on the NIAID Category A-C priority pathogens list and organisms…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
PETER MYLER · SEATTLE CHILDREN'S HOSPITAL · 2021 · $584,724 — The goal of the Structural Genomics Centers for Infectious Diseases is to apply state-of-the-art, high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins on the NIAID Category A-C priority pathogens list and organisms…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
DANIEL K. BENJAMIN · DUKE UNIVERSITY · 2021 · $38,494,599 — ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel betacoronavirus that first emerged in December 2019 and has since caused a global pandemic unseen in almost a century with respect to the number of cases and overall mortality. Over 2020, advances were made for treatmen…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Mohamed Abdel Mohsen · RUSH UNIVERSITY MEDICAL CENTER · 2021 · $215,870 — PROJECT SUMMARY Recent data show that 10-30% of coronavirus disease 2019 (COVID-19) patients do not fully recover and suffer from a wide range of symptoms that persist after the SARS-CoV-2 infection has been cleared (so-called post- COVID-19 syndrome or Long Hauler). Severe COVID-19 and associated r…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Robert D Bullard · DEEP SOUTH CENTER FOR ENVIRONMENTAL JUSTICE, INC. · 2021 · $268,524 — Project Summary/Abstract The Historically Black Colleges/Universities and Communities Consortium (HBCUCC) is directed by the Deep South Center for Environmental Justice (DSCEJ) in New Orleans, Louisiana, in partnership with the Barbara Jordan Mickey Leland School of Public Affairs at Texas Southern…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Robyn S. Klein · WASHINGTON UNIVERSITY · 2021 · $868,760 — PROJECT SUMMARY/ABSTRACT Viral infections are now recognized as risk factors for diseases of progressive pathological forgetting, supporting a new paradigm in neuroimmunology whereby innate immune molecules that function as modulators of a variety of normal CNS functions induce neurodegenerative dis…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
David M Koelle · UNIVERSITY OF WASHINGTON · 2021 · $264,749 — Summary The acquired, antigen-specific immune response to SARS-CoV-2-infection is likely central to determining the outcome of COVID-19 and the efficacy and durability of vaccination. CD4 T cell help is required for lasting, avid antibody responses. The leading vaccine candidates include some format…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Benjamin Scott Lepene · CERES NANOSCIENCES, LLLP · 2021 · $162,371 — PROJECT SUMMARY SARS-CoV-2 is the β-coronavirus causing the current coronavirus disease 2019 (COVID-19) outbreak. Large- scale diagnostic testing and large-scale screening are key tools used to contain outbreaks, and are especially important for something as transmissible as SARS-CoV-2. While variou…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
STEVEN A BENNER · FOUNDATION FOR APPLIED MOLECULAR EVOLUTN · 2021 · $313,900 — Easily Used Kits to Evolve Reagents that Covalently Tag and Inactivate Proteins Foundation for Applied Molecular Evolution Steven Benner ABSTRACT Under PAR-19-253, the NIGMS seeks new technologies that create a positive feedback loop that drives science forward by allowing new questions to be ask…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
PAUL JOSEPH UTZ · STANFORD UNIVERSITY · 2021 · $158,000 — 7. Project Summary/Abstract The overarching goal of this New Aim 4 is to test the hypothesis that SARS-CoV-2 (CoV-2) causes autoimmune disease (AI) in a subset of infected patients. Our preliminary studies on 336 COVID-19 samples from 282 COVID19 patients (four COVID-19 cohorts in three geographical…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
CHRISTIAN FORST · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2021 · $211,875 — Project Summary Emergent viral infections, such as SARS-CoV-2 and new influenza strains, pose an enormous health and economic burden on patients and the society. Viral cycles between the animal reservoir and the human population cause millions of hospitalizations and thousands of deaths each year, …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Jean-Laurent Casanova · ROCKEFELLER UNIVERSITY · 2021 · $446,039 — Project Summary In December 2019, a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, China, and quickly spread worldwide, with an increasing number of cases and deaths. In populations naive to this new pathogen, there has been immense inter-individual clinical variability among infected …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Reynold Alexander Panettieri · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · 2021 · $1,200,946 — SUMMARY The COVID-19 pandemic disproportionately impacts members of under-represented minority (URM) communi- ties. Unfortunately, URM and other vulnerable communities remain profoundly under-tested. As such, new ap- proaches are needed to disseminate and accomplish testing that could be generalized…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Leonard A Jason · DE PAUL UNIVERSITY · 2021 · $282,868 — Abstract Behavioral and pathophysiological underpinnings of the development of COVID-19 are poorly understood. From 2014 through 2018, our research group collected psychological and biological data of 4,501 young adults. We are currently funded to re-contact and interview these subjects regarding sy…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Scott C Weaver · UNIVERSITY OF TEXAS MED BR GALVESTON · 2021 · $987,497 — ABSTRACT As underscored by pandemic COVID-19, Zika, yellow fever and chikungunya viruses, new and emerging viruses represent increasing threats to human health, yet their mechanisms of emergence remain poorly understood, and effective interventions are not available for most. Research on their patho…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Pamina Mae Gorbach · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2021 · $400,898 — ABSTRACT In response to RFA-DA-17-019 we propose to establish a Coordinating Center for the NIDA Cohorts entitled “C3NPO” * to manage and stimulate use of the data generated to address high priority research on HIV/AIDS in the context of substance abuse. Our focus is cutting-edge science powered by …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
Gloria David · RHO FEDERAL SYSTEMS DIVISION, INC. · 2021 · $15,843,849 — PROJECT SUMMARY / ABSTRACT The SARS-CoV-2 virus has triggered a world-wide pandemic with over 28 million cases and more than 500,000 deaths in the United States as of March 1, 2021 (Centers for Disease Control and Prevention, COVID Data Tracker). The Food and Drug Administration (FDA) has given Emer…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2021
DANIEL K. BENJAMIN · DUKE UNIVERSITY · 2021 · $77,049,200 — ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel betacoronavirus that first emerged in December 2019 and has since caused a global pandemic unseen in almost a century with respect to the number of cases and overall mortality. Over 2020, advances were made for treatmen…