NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2022 · $4,251,842 — West Virginia (WV), the only state located entirely in Appalachia, has the lowest life expectancy in the nation and ranks at or near the bottom in many chronic disease categories. The WV Clinical and Translational Science Institute (WVCTSI) was created in 2012 through the initial Institutional Devel…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Mariano Juan Kanamori Nishimura · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2022 · $777,784 — PROJECT SUMMARY/ABSTRACT LatiNET will use a multilevel social network model to examine how SARS-CoV-2 misinformation and Conspiracy Theory (CT) messages are shared across five settings (friends, family, work, health service and influencers), impacting Latinx vaccine hesitancy. Social networks are se…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Amir Kol · UNIVERSITY OF CALIFORNIA AT DAVIS · 2022 · $196,510 — This R21 proposes to fill a major scientific gap by investigating a new therapeutic approach for multisystem inflammatory syndrome in children (MIS-C) using an innovative and clinically relevant feline model. We propose to test a novel multi-pronged therapeutic paradigm targeting viral replication, …
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
ALBERTO ASCHERIO · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2022 · $483,619 — PROJECT SUMMARY The highest priority recommended by NINDS for clinical Parkinson’s research is to define “the features and natural history of prodromal Parkinson disease (PPD), including the events that underlie phenoconversion to clinically manifest PD, and biomarkers or other determinants of prodr…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
MANUEL R AMIEVA · STANFORD UNIVERSITY · 2022 · $1,511,551 — Stanford/UNC Biomimetic U19 Research Center PROJECT SUMMARY/ABSTRACT – CENTER OVERVIEW Infectious diseases continue to pervasively afflict global health and socioeconomic stability despite substantial prevention and treatment initiatives. Respiratory and gastrointestinal pathogens rank amongst the m…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Robyn S. Klein · WASHINGTON UNIVERSITY · 2022 · $1,181,250 — PROJECT SUMMARY/ABSTRACT Viral infections are now recognized as risk factors for diseases of progressive pathological forgetting, supporting a new paradigm in neuroimmunology whereby innate immune molecules that function as modulators of a variety of normal CNS functions induce neurodegenerative dis…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Farhang Alem · GEORGE MASON UNIVERSITY · 2022 · $4,039,853 — Project Summary/Abstract: The ongoing COVID pandemic has demonstrated the need for state-of-the-art facilities and infrastructure to improve our preparedness for subsequent epidemics and/or pandemics. George Mason University (GMU), leveraging the Regional Biocontainment Laboratory, designated as the…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Anilkumar Pillai · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 2022 · $445,694 — Chronic stress is a risk factor for the development of multiple psychiatric disorders for which current treatments are inadequate. Evidence from our laboratory and others suggest that chronic stress can also provoke elevated inflammation and exaggerated inflammatory responses in both humans and anim…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Rebecca Bradford · AMERICAN TYPE CULTURE COLLECTION · 2022 · $3,862,721 — Project Summary: The proposed project aims to renovate ATCC's High Containment Facility (HCF) at the American Type Culture Collection (ATCC) in Manassas, Virginia. ATCC's 7,500 ft2 biocontainment facility was built in 2007 with funding from NIAID and has been dedicated to developing infectious disea…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
sandra Paige story · NUBAD, LLC · 2022 · $299,900 — PROJECT SUMMARY The world is immersed in a health crisis rivaled only by the Spanish flu pandemic of 1918-1919. The difference between the crisis of today and the crisis a century ago is that we have advanced communication technology greatly so that huge populations of people around the globe are aw…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Margaret Juliana McElrath · FRED HUTCHINSON CANCER CENTER · 2022 · $929,677 — Abstract: With the rapid onset of the COVID-19 pandemic, we recognize there is a significant gap in knowledge in the field on the contribution of immune functions involved in preventing infection, in modifying COVID-19 disease, and in clearing viral infection. We believe the HVTN is well placed to s…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Sally Lynn Hodder · WEST VIRGINIA UNIVERSITY · 2022 · $645,360 — Electronic Health Record (EHR) data collected during routine clinical care offer real world evidence to support decision making and observational research. The National COVID Cohort Collaborative (N3C) is a centralized national EHR data resource for the study of COVID-19 patient outcomes. Centers su…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
DEAN R MADDEN · DARTMOUTH COLLEGE · 2022 · $2,460,000 — The Dartmouth Institute for Biomolecular Targeting (bioMT) infuses mechanistic investigations with a sophisticated awareness of disease pathology and therapeutic need, enhancing the quality of even the most fundamental research. At the same time, it helps orient mechanistic investigations towards lo…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Dennis A Bente · THOMAS JEFFERSON UNIVERSITY · 2022 · $779,687 — Crimean-Congo hemorrhagic fever virus (CCHFV) causes severe disease in humans, with fatality rates reaching 40%. CCHFV is endemic to parts of Africa, Asia, the Middle East, and Europe, specifically to regions where the tick vector, species of the Hyalomma genus, is present. Classified as an NIH/NIAI…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Patricia L Hibberd · BOSTON UNIVERSITY MEDICAL CAMPUS · 2022 · $568,497 — Coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS- CoV-2) was first reported in Wuhan, Hubei Province of China in December 2019 and by early 2021, there have been more than 100 million cases of COVID-19 globally. The consequences of COVID-19 in preg…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Jonathan B Overdevest · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2022 · $178,610 — PROJECT SUMMARY Smell loss is a common neurosensory disability accompanying infection with SARS-CoV-2 novel coronavirus. The frequency and persistence of alteration in the ability to smell, or olfactory dysfunction (OD), observed during the COVID-19 pandemic highlight a knowledge gap, where risk fac…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Margaret Leighton McNairy · WEILL MEDICAL COLL OF CORNELL UNIV · 2022 · $124,224 — ABSTRACT: The goals of this K24 proposal are to train clinical investigators in the conduct of patient-oriented cardiovascular disease (CVD) research primarily in Haiti, with a new project in Tanzania and to conduct a new study on environmental lead exposure and CVD risk factors in Haiti (Aim 1). Th…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Benjamin F Arnold · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2022 · $723,537 — Enteric pathogen infections are a leading cause of the global disease burden, with the largest burden among children in low-resource settings. Stool-based PCR methods have dramatically improved our ability to measure enteric infections, but the challenge of collecting stool and need for near-continu…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
JOHN BILLIMEK · UNIVERSITY OF CALIFORNIA-IRVINE · 2022 · $595,273 — Project Abstract Community health workers (CHWs) played an essential role in addressing multi-level, community barriers to accessing COVID-19 information, testing, risk mitigation, and vaccination; however, little is known about how CHWs managed their roles in light of enormous social, community, an…
NIH Pandemic-Era Grants
· Pandemic Era Grants
/ 2022
Michelle Weiss Katzow · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · 2022 · $190,836 — PROJECT SUMMARY/ABSTRACT This Mentored Patient-Oriented Research Career Development Award (K23) proposal will address an urgent need to advance the science of child obesity prevention in low-income, minority communities, a priority of the National Heart, Lung, and Blood Institute. Simultaneously, it…