125742 S1 M5 5351 bnt162 01 interim3 discontinued patients

Pfizer Documents (PHMPT/FDA)

Pfizer Bla Submission

Pfizer 16 Plus Documents

2

Document text

Bio
NTech RNA Pharmaceuticals GmbH /  Listi
ngs - 6. Sn
apshot All TLFs Final 1.0  BNT16
2b1 
BNT16
2-01 Created
 on 20NOV2020   
 
 
 
 
 
 
Staburo G
mbH. Based on clean SDTM data received on 03NOV2020. Data cut -off: 23O
CT2020.  Listing
 16.2.1 -3-1: 
Listing of subjects with premature discontinuation - BNT
162b1  
Safety
 set 
 
Dose g
roup Subj
ect number  Date o
f last 
vis
it/contact  Date o
f premature 
termi
nation  Mai
n reason for premature termination  Epi/ 
Pandemic 
rela
ted 
10 µg
 Younger  10010  22M
AY2020  19M
AY2020  Adve
rse Event  No 
20 µg
 Younger  10178  09SEP2
020 09SEP2
020 Othe
r (private reason)  No 
10182  06O
CT2020  23J
UL2020  Wit
hdrawal By Subject  No 
50 µg
 Younger  10050  03J
UN2020  03J
UN2020  Othe
r (due to private reason.)  No 
 
Progra
m: Lba
se_Disp_3.sas          (Page 1 of 1) 
090177e1959f772d\Approved\Approved On: 27-Nov-2020 03:38 (GMT) 
Page 1
FDA-CBER-2021-5683-0049417
Bio
NTech RNA Pharmaceuticals GmbH /  Listi
ngs - 6. Sn
apshot All TLFs Final 1.0  BNT16
2b2 
BNT16
2-01 Created
 on 20NOV2020   
 
 
 
 
 
 
Staburo G
mbH. Based on clean SDTM data rece
ived on 03NOV2020. Data cut -off: 23O
CT2020.  Listing
 16.2.1 -3-3: 
Listing of subjects with premature discontinuation - BNT
162b2  
Safety
 set 
 
Dose g
roup Subj
ect number  Date o
f last 
vis
it/contact  Date o
f premature 
termi
nation  Mai
n reason for premature termination  Epi/ 
Pandemic 
rela
ted 
1 µg Y
ounger  20160  31J
UL2020  30J
UL2020  Wit
hdrawal By Subject  No 
10 µg
 Younger  20116  04AUG
2020  16J
UL2020  Adve
rse Event  No 
 
Progra
m: Lba
se_Disp_3.sas          (Page 1 of 1) 
090177e1959f772e\Approved\Approved On: 27-Nov-2020 03:38 (GMT) 
Page 2
FDA-CBER-2021-5683-0049418