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Pfizer Documents (PHMPT/FDA)

Pfizer Bla Submission

Pfizer 16 Plus Documents

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Document text

PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 1 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited. Topic  Script Verbiage and Logic 
1.0 Live Operator Script  Welcome for PP-CVV- USA -0303  
1.0 Welcome  1.1 Good (Morning/Afternoon/Evening) and thank you for calling the customer service 
center for the Pfizer -BioNTech COVID -19 vaccine, also known as COMIRNATY® 
(COVID -19 Vaccine, mRNA)*.  
 
*The licensed COMIRNATY® vaccine has the same formulation as the authorize d 
vaccine Pfizer- BioNTech Covid- 19 Vaccine, and the products can be used 
interchangeably to provide the vaccination series without presenting any safety or  
effectiveness  concerns.  The products  are legally  distinct,  with certain  differences  
that  do not impact safety or  effectiveness.  
 
My name is . How may I  help you today?  
 Before  we continue,  I need  to share the following  important  safety  information  with                  
you…  
 COMIRNATY®  (COVID -19 Vaccine, mRNA) is an FDA -approved COVID -19 
vaccine made by Pfizer for BioNTech.  
 
• It is approved  as a 2-dose  series  for prevention of COVID -19 in 
individuals  16 years  of age and older  
• It is also authorized under  Emergency  Use Authorization (EUA) to be 
administered for emergency use to: 
o prevent  COVID -19 in individuals  12 through 15 years,  and 
o provide a third dose to individuals  12 years  of age and older  who 
have been  determined  to have certain kinds  of 
immunocompromise  
 
The Pfizer -BioNTech  COVID -19 Vaccine  has received  EUA from FDA to: 
• prevent  COVID -19 in individuals  12 years  of age and older,  and 
• provide a third dose to individuals  12 years  of age and older  who have  
been  determined to have certain kinds  of immunocompromise  
 
The FDA -approved COMIRNATY ® (COVID -19 Vaccine, mRNA) and the EUA- 
authorized Pfizer -BioNTech COVID -19 Vaccine have  the same  formulation and 
can  be used interchangeably to provide the COVID- 19 vaccination series. An 
individual   may be offered either COMIRNATY ® (COVID -19 Vaccine, mRNA) or 
the Pfizer -BioNTech COVID -19 Vaccine to prevent coronavirus disease 2019 
(COVID -19) caused by SARS -CoV-2. 
 
The emergency use of the product has not been approved or licensed by FDA, but has been authorized by FDA, under an Emergency Use Authorization (EUA) to prevent Coronavirus Disease 2019 (COVID -19) for use in individuals 
12 years of age and older; and the emergency use of  this product is only 
authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of the medical product under Section 564(b)(1) of the FD&C Act unless the declaration is terminated or authorization 
revoked sooner.  This is an update to PP -CVV-
USA-0303, Section 1.0 
Greeting. Only the updated 
section has been submitted. 
Please see live operator map 
on page 7 for a detailed 
explanation of the section that 
has been updated and PP -
CVV-USA -0303 for the 
remaining pages. PP -CVV -
USA-0303 has been submitted 
to CBER with copy to APLB on 
08/04/2021  
FDA-CBER-2021-5683-0951443
PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 2 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited. You should not get the Pfizer -BioNTech COVID -19 Vaccine if you: 
• had a severe  allergic  reaction after a previous  dose of this  vaccine  
• had a severe  allergic  reaction to any ingredient  of this vaccine  
 
Tell the vaccination provider  about  all of your medical  conditions,  including if you: 
• have any allergies  
• have had myocarditis  (inflammation  of the heart  muscle)  or pericarditis 
(inflammation of  the lining  outside the heart)  
• have a fever  
• have a bleeding disorder  or are on a blood thinner  
• are immunocompromised or are on a medicine that affects  your 
immune     system  
• are pregnant,  plan to become pregnant,  or are breastfeeding  
• have received  another COVID -19 vaccine  
• have ever fainted in association with an injection   
The vaccine  may not  protect  everyone.  
Side effects  reported with the vaccine  include:  
There is a remote  chance that the vaccine  could cause  a severe  allergic     reaction  
 
• A severe allergic reaction would usually occur within a few minutes to one 
hour after getting a dose of the vaccine.  For this reason,  your     vaccination 
provider may ask you to stay at the place where you received your 
vaccine  for monitoring after vaccination  
 
▪ Signs of a severe allergic reaction can include difficulty 
breathing,  swelling of your face and throat, a fast heartbeat, a 
bad rash all over  your body,  dizziness,  and weakness  
 
▪ If you experience a severe allergic reaction, call 9-1- 1 or go 
to the   nearest  hospital  
 
• Myocarditis (inflammation of the heart muscle) and pericarditis 
(inflammation   of the lining outside the heart) have occurred in some 
people who have received the vacc ine. In most of these people, 
symptoms began within a few   days following receipt of the second 
dose of the vaccine. The chance of  having this occur  is very low. You 
should seek  medical  attention  right away  if  you have any  of the 
following  symptoms  after receiving the vaccine:  
 
▪ chest  pain 
 
FDA-CBER-2021-5683-0951444
PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 3 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited. ▪ shortness  of breath  
 
▪ feelings  of having a fast-beating,  fluttering,  or pounding heart  
 
• Side effects  that have been reported with the vaccine  include:  
 
▪ severe  allergic  reactions;  non-severe  allergic  reactions  such  as 
rash,  itching, hives, or swelling of the face; myocarditis 
(inflammation of  the heart muscle); pericarditis (inflammation of 
the lining outside the heart); injection site pain; tiredness; 
headache; muscle pain; chills;  joint pain; fever; injection site 
swelling; injection site redness;  nausea; feeling unwell; swollen 
lymph nodes (lymphadenopathy);  diarrhea;  vomiting;  arm pain 
 
• These may not be all the possible side effects of the vaccine. Serious and 
unexpected side effects may occur. The vaccine is still being studied in 
clinical  trials.  Call the vaccination provider  or your healthcare provider  if 
you have  any side effects  that bother  you or do not go away  
 
There is no  information on the use of this vaccine with other  vaccines.  
 
Patients should always ask their healthcare providers for medical advice about  
adverse events. Report negative side effects of vaccines to the US Food and Drug  
Administration (FDA) and the Centers for Disease Control and Prevention (CDC).  
Visit http://www.vaers.hhs.gov or call 1 ‐800‐822 ‐7967. In addition, you can report  
side effects to Pfizer Inc. at www.pfizersafetyreporting.com or by calling 1 -800-
438- 1985.  
 Please visit www.comirnaty.com for full Prescribing Information (16+ years of age) 
and Recipient  and Caregiver Fact Sheet  (12+ years  of age).  
 
                                                                                                         PP-CVV -USA-0378-01 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
FDA-CBER-2021-5683-0951445
PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 4 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited. 1.0 IVR Script Welcome  for PP -CVV-USA -0304  
1.1 Welcome Transfers from Pfizer Trade IVR for PP -CVV-USA -0304  
1.0 
1. 1 Welcome    Thank you for calling the customer service center for the Pfizer -BioNTech    
  COVID -19      Vaccine,  also known as COMIRNATY®  (COVID- 19 Vaccine,     
  mRNA)*.  
 
*The licensed COMIRNATY® vaccine has the same formulation as the 
authorized vaccine Pfizer- BioNTech Covid -19 Vaccine, and the products can be 
used  interchangeably to provide the vaccination series without presenting any 
safety or  effectiveness  concerns.  The products  are legally  distinct,  with certain 
differences  that  do not impact  safety or  effectiveness.  
 
Before  we continue,  I need  to share the following  important  safety  information  
with  you…  
 
COMIRNATY ® (COVID- 19 Vaccine, mRNA) is an FDA -approved COVID -19 
vaccine         made by Pfizer for  BioNTech.  
 
• It is approved  as a 2-dose  series  for prevention of COVID -19 in individuals  
16 years  of age and older  
 
• It is also authorized under  Emergency  Use Authorization (EUA) to be 
administered for emergency use to: 
 
▪ prevent  COVID -19 in individuals  12 through 15 years,  and 
▪ provide a third dose to individuals  12 years  of age and older  
who  have  been determined to have certain kinds of  
immunocompromise  
 The Pfizer -BioNTech  COVID -19 Vaccine  has received  EUA from FDA to: 
• prevent  COVID -19 in individuals  12 years  of age and older,  and 
• provide a third dose to individuals  12 years  of age and older  who have  
been  determined to have certain kinds  of immunocompromise  
 
The FDA -approved COMIRNATY ® (COVID -19 Vaccine, mRNA) and the EUA - 
authorized Pfizer -BioNTech COVID -19 Vaccine have  the same  formulation and 
can  be used interchangeably to provide the COVID- 19 vaccination series. An 
individual   may be offered either COMIRNATY ® (COVID -19 Vaccine, mRNA) or 
the Pfizer -BioNTech COVID -19 Vaccine to prevent coronavirus disease 2019 
(COVID -19) caused by SARS -CoV-2. 
 
The eme 
rgency use of the product has not been approved or licensed by FDA, 
but has been authorized by FDA, under an Emergency Use Authorization (EUA) 
to prevent Coronavirus Disease 2019 (COVID -19) for use in individuals 12 years 
of age and older; and the emergency use of this product is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of the medical product under Section 564(b)(1) of the FD&C Act 
unless the declaration is terminated or authorization revoked sooner.  
 This is an update to PP -CVV-
USA-0304, Section 1.0 
Welcome and Section 1.1 
Welcome Transfers from Pfizer 
Trade IVR. Only the updated 
sections have been submitted. 
Please see IVR map on page 
8 for a detailed explanation of 
the section that has been 
updated and PP -CVV -USA -
0304 for the remaining pages. 
PP-CVV -USA -0304 has been 
submitted to CBER with copy 
to APLB on 08/04/2021  
FDA-CBER-2021-5683-0951446
PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 5 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited.  
You should not get the Pfizer -BioNTech COVID -19 Vaccine if you: 
• had a severe  allergic  reaction after a previous  dose of this vaccine  
• had a severe  allergic  reaction to any ingredient  of this vaccine  
 
Tell the vaccination provider  about  all of your medical  conditions,  including if you: 
• have any allergies  
• have had myocarditis  (inflammation  of the heart  muscle)  or 
pericarditis   (inflammation of  the lining  outside the heart)  
• have a fever  
• have a bleeding disorder  or are on a blood thinner  
• are immunocompromised or are on a medicine that affects your 
immune  system  
• are pregnant,  plan to become pregnant,  or are breastfeeding  
• have received  another COVID -19 vaccine  
• have ever fainted in association with an injection  
 The vaccine  may not protect  everyone.  
  Side  effects  reported with the vaccine  include:  
• There is a remote chance that the vaccine  could cause  a severe 
allergic      reactio n  
▪ A severe  allergic  reaction would usually occur within  a few 
minutes to one hour after getting a dose of the vaccine.  
For this reason,  your  vaccination provider  may ask you to 
stay at the place where  you received your vaccine  for 
monitoring after vaccination  
▪ Signs of a severe allergic reaction can include difficulty 
breathing,  swelling  of your face and throat,  a fast 
heartbeat,  a bad rash all over  your body,  dizziness,  and 
weakness  
▪ If you experience a severe allergic reaction, call 9-1- 1 or 
go to the  nearest  hospital  
 
• Myocarditis (inflammation of the heart muscle) and pericarditis 
(inflammation   of the lining outside the heart) have occurred in some 
people who have received the vacc ine. In most of these people, 
symptoms began within a few   days following receipt of the second 
dose of the vaccine. The chance of  having this occur  is very low. You 
should seek  medical  attention  right away  if    you have any  of the 
following  symptoms  after receiving the vaccine:  
 
▪ chest  pain 
FDA-CBER-2021-5683-0951447
PFIZER  
Pfizer-BioNTech COVID -19 Vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings  
PP-CVV -USA-0378 
877-829-2619 (877-VAX -CO19)  
                                                  
 
PP-CVV-USA-0378_Pfizer-BioNTech Covid-19 Vaccine  also known as Comirnaty_IVR and Live Operator Script_Greetings   Page 6 of 6  
 
Confidential Pfizer document - for internal use only.   
Reproduction and/or distribution of this document for any purpose without express written consent from Pfizer is proh bited.  
▪ shortness  of breath  
 
▪ feelings  of having a fast-beating,  fluttering,  or pounding heart  
 
 
• Side effects that have been reported with the vaccine include:  
 
▪ severe allergic reactions; non- severe allergic reactions such as 
rash, itching, hives, or swelling of the face; myocarditis 
(inflammation of the heart muscle); pericarditis (inflammation of the lining outside the heart); injection site pain; tiredness; 
headache; muscle pain; chills; joint pain; fever; injection site 
swelling; injection site redness; nausea; feeling unwell; swollen lymph nodes (lymphadenopathy); diarrhea; vomiting; arm pain.  
 
• These may not be all the possible side effects of the vaccine. Serious and unexpected side effects may occur. The vaccine is still being studied in 
clinical  trials.  Call the vaccination provider  or your healthcare provider  if 
you have  any side effects  that bother  you or do not go away  
 
There is no  information on the use of this vaccine with other  vaccines.  
 
Patients should always ask their healthcare providers for medical advice about  
adverse events.  Report  negative side effects  of vaccines  to the US Food and Drug         
Administration (FDA) and the Centers for Disease Control and Prevention (CDC).  
Visit http://www.vaers.hhs.gov  or call 1 ‐800‐822 ‐7967.  In addition,  you can report 
side effects  to Pfizer  Inc. at www.pfizersafetyreporting.com  or by calling  1-800-
438-1985.  
 
Please visit www.comirnaty.com for full Prescribing Information (16+ years of age)  
and Recipient  and Caregiver Fact Sheet  (12+ years  of age).  
 
                                                                                           PP-CVV-USA-0378 -02 
 
FDA-CBER-2021-5683-0951448
 
FDA-CBER-2021-5683-0951449
 
FDA-CBER-2021-5683-0951450