125742 S118 M1 pp cvv usa 0426

Pfizer Documents (PHMPT/FDA)

Pfizer Bla Submission

Pfizer 16 Plus Documents

8

Document text

PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 1 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
  
 
 
1.0 Live Operator Script  Welcome for PP-CVV -USA- 0303  
1.0 New Greeting  
 
 
 
 1.1 Good (Morning/Afternoon/Evening) and thank you for calling the customer service  
center  for the Pfizer -BioNTech COVID-19 vaccine, also known as COMIRNATY® 
(COVID-19 Vaccine, mRNA).  
*The licensed COMIRNATY® vaccine has the same formulation as the authorized 
vaccine Pfizer -BioNTech Covid-19 Vaccine, and the products can be used 
interchangeably to provide the vaccination series without  presenting any safety or  
effectiveness  concerns.  The products  are legally  distinct,  with certain differences  that 
do not impact  safety or  effectiveness.  
The emergency uses of the vaccine have not been approved or licensed by FDA, but have been authorized by FDA, under an Emergency Use Authorization (EUA) to 
prevent Coronavirus Disease 2019 (COVID-19) for use in individuals 12 years of age 
and older. The emergency uses are only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of the medical product under Section 564(b)(1) of the FD&C Act unless the declaration is terminated or authorization revoked sooner.  
My name is . How may I  help you today?  
Before we continue,  I need to share the following important  safety  information with 
you…  
 
INDICATION & AUTHORIZED USE  
 HOW IS THE VACCINE GIVEN?  
 The vaccine will be given to you as an injection into the muscle.  
 
Primary Series: The vaccine is administered as a 2-dose series, 3 weeks apart. A third 
dose may be administered at least 4 weeks after the second dose to individuals who are determined to have certain kinds of immunocompromise.  
 Booster Dose: A single booster dose of the vaccine may be administered to individuals:  
• 65 years of age and older  
• 18 through 64 years of age at high risk of severe COVID-19 
• 18 through 64 years of age whose frequent institutional or occupational exposure to SARS -CoV -2 puts them at high risk of serious complications of 
COVID -19 including severe COVID‑ 19 
 
WHAT IS THE INDICATION AND AUTHORIZED USE?  
 
The FDA -approved COMIRNATY® (COVID-19 Vaccine, mRNA) and the FDA -
authorized Pfizer -BioNTech COVID-19 Vaccine under Emergency Use Authorization 
(EUA) have the same formulation and can be used interchangeably to provide the COVID -19 vaccination series  
 COMIRNATY® (COVID-19 Vaccine, mRNA) is an FDA -approved COVID-19 vaccine 
made by Pfizer for BioNTech.  
• It is approved as a 2-dose series for prevention of COVID-19 in individuals 16 years of age and older  
• It is al so authorized under EUA to provide:  This is an update to PP -CVV-
USA-0303, Section 1.0 
Greeting and replaces PP -
CVV-USA -0378-01 Section 
1.0. Only the updated section has been submitted. Please see live operator map on page 7 for a detailed explanation of 
the section that has been 
updated and PP -CVV -USA -
0303 for the remaining pages. 
PP-CVV -USA -0303 has been 
submitted to CBER with a copy to APLB on 08/04/2021 
 
 
FDA-CBER-2021-5683-0951793
PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 2 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
 • a two -dose primary series in individuals 12 through 15 years  
• a third primary series dose in individuals 12 years of age and older 
who have been determined to have certain kinds of immunocompromise  
• a single booster dose in individuals:   
o 65 years of age and older  
o 18 through 64 years of age at high risk of severe COV ID-19 
o 18 through 64 years of age whose frequent institutional or occupational exposure to SARS -CoV -
2 puts them at high risk 
of serious complications of COVID-19 including severe 
COVID ‑19 
 
The Pfizer -BioNTech COVID-19 Vaccine has received EUA from FDA to pr ovide:  
• a two-dose primary series in individuals 12 years of age and older  
• a third primary series dose for individuals 12 years of age and older who have 
been determined to have certain kinds of immunocompromise  
• a single booster dose in individuals:  
• 65 years of age and older  
• 18 through 64 years of age at high risk of severe COVID-19 
• 18 through 64 years of age whose frequent institutional or occupational exposure to SARS -CoV -2 puts them at high risk of 
serious complications of COVID-19 including severe COVI D‑19 
 
IMPORTANT SAFETY INFORMATION  
 You should not get the vaccine if you:  
• had a severe allergic reaction after a previous dose of this vaccine 
• had a severe allergic reaction to any ingredient of this vaccine  
 Tell the vaccination provider about all of your medical conditions, including if you:  
• have any allergies  
• have had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart)  
• have a fever  
• have a bleeding disorder or are on a blood thinner   
• are immunocompromised or are on a medicine that affects your immune system 
• are pregnant, plan to become pregnant, or are breastfeeding  
• have received another  COVID -19 vaccine 
• have ever fainted in association with an injection 
 The vaccine may not protect everyone.  
 Side effects reported with the vaccine include:  
• There is a remote chance that the vaccine could cause a severe allergic reaction.  
• A severe allergic reaction would usually occur within a few minutes to one hour after getting a dose of the vaccine. For this reason, your vaccination provider may ask you to stay at the place where you received your vaccine for monitoring after vaccination 
• Signs of a severe allergic reaction can include difficulty breathing, swelling of your face and throat, a fast heartbeat, a bad rash all over your body, dizziness, and weakness  
• If you experience a severe allergic reaction, call 9-1-1 or go to the 
nearest hospital  
FDA-CBER-2021-5683-0951794
PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 3 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
  
• Myocarditis (inflammation of the heart muscle) and pericarditis (inflammation 
of the lining outside the heart) have occurred in some people who have received the vaccine. In most of these people, symptoms began within a few days following receipt  of the second dose of the vaccine. The chance of 
having this occur is very low. You should seek medical attention right away if you have any of the following symptoms after receiving the vaccine:  
• chest pain 
• shortness of breath 
• feelings of having a fast -beating, fluttering, or pounding heart  
 
• Side effects that have been reported with the vaccine include:  
• severe allergic reactions; non-severe allergic reactions such as rash, 
itching, hives, or swelling of the face; myocarditis (inflammation of the 
heart muscle); pericarditis (inflammation of the lining outside the heart); injection site pain; tiredness; headache; muscle pain; chills; 
joint pain; fever; injection site swelling; injection site redness; nausea; 
feeling unwell; swollen lymph nodes (lymphadenopathy); decreased appetite; diarrhea; vomiting; arm pain; fainting in association with injection of the vaccine  
 
• These may not be all the possible side effects of the vaccine. Serious and unexpected side effects may occur. The possible side effects of the vac cine 
are still being studied in clinical trials. Call the vaccination provider or your healthcare provider if you have any side effects that bother you or do not go away  
 
Data on administration of this vaccine at the same time as other vaccines have not ye t 
been submitted to FDA. If you are considering receiving this vaccine with other vaccines, discuss your options with your healthcare provider.  
 
Patients should always ask their healthcare providers for medical advice about adverse events. Report negative side effects of vaccines to the US Food and Drug 
Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit 
http://www.vaers.hhs.gov or call 1 ‑800 ‑822 ‑7967. In addit ion, you can report side 
effects to Pfizer Inc. at www.pfizersafetyreporting.com or by calling 1-800-438-1985.  
 For the most recent full Prescribing Information (16 + years of age), EUA Fact Sheet for Vaccination Providers (12+ years of age) , and Recipient s and Caregiver s Fact 
Sheet (12 + years of age) please visit www.Comirnaty.com
  
 
PP-CVV -USA -0426- 01 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FDA-CBER-2021-5683-0951795
PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 4 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
  
1.0 IVR Script  Welcome  and 1.1 Welcome Transfers from Pfizer Trade IVR for PP-CVV -0304 
   New Greeting       
callrecording  
 
  Thank you for calling the customer service  center for the Pfizer -BioNTech 
COVID -19 vaccine, also known as COMIRNATY® (COVID-19 Vaccine, mRNA).  
*The licensed COMIRNATY® vaccine has the same formulation as the authorized 
vaccine Pfizer -BioNTech Covid-19 Vaccine, and the products can be used 
interchangeably to provide the vaccination series without presenting any safety or  
effectiveness  concerns.  The products  are legally  distinct,  with certain differences  that 
do not impact  safety or  effectiveness.  
The emergency uses of the vaccine have not been approved or licensed by FDA, but have been authorized by FDA, under an Emergency Use Authorization (EUA) to 
prevent Coronavirus Disease 2019 (COVID-19) for use in individuals 12 years of age 
and older. The emergency uses are only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of the medical product under Section 564(b)(1) of the FD&C Act unless the declaration is terminated or authorization revoked sooner.  
 Before we continue,  I need to share the following important  safety  information with 
you…  
 
INDICATION & AUTHORIZED USE  
 
HOW IS THE VACCINE GIVEN?  
 
The vaccine will be given to you as an injection into the muscle.  
 
Primary Series: The vaccine is administered as a 2- dose series, 3 weeks apart. A third 
dose may be administered at least 4 weeks after the second dose to individuals who are determined to have certain kinds of immunocompromise.  
 Booster Dose: A single booster dose of the vaccine may be administered to individuals:  
• 65 years of age and older  
• 18 through 64 years of age at high risk of severe COVID-19 
• 18 through 64 years of age whose frequent institutional or occupational exposure to SARS -CoV -2 puts them at high risk of serious complications of 
COVID -19 including severe COVID‑ 19 
 
WHAT IS THE INDICATION AND AUTHORIZED USE?  
 
The FDA -approved COMIRNATY® (COVID-19 Vaccine, mRNA) and the FDA -
authorized Pfizer -BioNTech COVID-19 Vaccine under Emergency Use Authorization 
(EUA) have the same formulation and can be used interchangeably to provide the COVID -19 vaccination series  
 COMIRNATY® (COVID-19 Vaccine, mRNA) is an FDA -approved COVID-19 vaccine 
made by Pfizer for BioNTech.  
• It is approved as a 2-dose series for prevention of COVID-19 in individuals 16 years of age and older  
• It is also authorized under EUA to provide:  
• a two-dose primary series in individuals 12 through 15 years  
• a third primary series dose in individuals 12 years of age and older 
who have been determined to have certain kinds of 
immunocompromise  This is an update to PP -CVV-
USA-0304, Section 1.0 
Welcome and 1.1 Welcome 
Transfers from Pfizer Trade 
IVR and replaces PP -CVV -
USA-0378-02 Section 1.0 IVR 
Script Welcome and 1.1 Welcome Transfers from Pfizer Trade IVR for PP -CVV -USA -
0304. Only the updated section has been submitted. Please see live operator map on page 8 for a detailed explanation of 
the section that has been updated and PP -CVV -USA -
0304 for the remaining pages. PP-CVV -USA -0304 has been 
submitted to CBER with a copy to APLB on 08/04/2021 
 
 
FDA-CBER-2021-5683-0951796
PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 5 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
 • a single booster dose in individuals:   
o 65 years of age and older  
o 18 through 64 years of age at high risk of severe COVID-19 
o 18 through 64 years of age whose frequent institutional or 
occupational exposure to SARS -CoV -2 puts them at high risk 
of serious complications of COVID-19 including severe 
COVID ‑19 
 
The Pfizer -BioNTech COVID-19 Vaccine has received EUA from FDA to provide:  
• a two-dose primary series in individuals 12 years of age and older  
• a third primary series dose for individuals 12 years of age and older who have 
been determined to have certain kinds of immunocompromise  
• a single booster dose in individuals:  
• 65 years of age and older  
• 18 through 64 years of age at high risk of severe COVID-19 
• 18 through 64 years of age whose frequent institutional or occupational exposure to SARS -CoV -2 puts them at high risk of 
serious complications of COVID-19 including severe COVID‑ 19 
 
IMPORTANT SAFETY INFORMATION  
 You should not get the vaccine if you:  
• had a severe allergic reaction after a previous dose of this vaccine 
• had a severe allergic reaction to any ingredient of this vaccine  
 Tell the vaccination provider about all of your medical conditions, including if you:  
• have any allergies  
• have had myocarditis (inflammation of the heart muscle) or pericarditis (inflammation of the lining outside the heart)  
• have a fever  
• have a bleeding disorder or are on a blood thinner   
• are immunocompromised or are on a medicine that affects your immune 
system 
• are pregnant, plan to become pregnant, or are breastfeeding  
• have received another COVID-19 vaccine 
• have ever fainted in association with an injection 
 The vaccine may not protect everyone.  
 Side effects reported with the vaccine include:  
• There is a remote chance that the vaccine could cause a severe allergic 
reaction.  
• A severe allergic reaction would usually occur within a few minutes to 
one hour after getting a dose of the vaccine. For  this reason, your 
vaccination provider may ask you to stay at the place where you received your vaccine for monitoring after vaccination 
• Signs of a severe allergic reaction can include difficulty breathing, swelling of your face and throat, a fast heartbeat, a bad rash all over 
your body, dizziness, and weakness  
• If you experience a severe allergic reaction, call 9-1-1 or go to the 
nearest hospital 
 
• Myocarditis (inflammation of the heart muscle) and pericarditis (inflammation of the lining outside the heart) have occurred in some people who have 
received the vaccine. In most of these people, symptoms began within a few 
FDA-CBER-2021-5683-0951797
PFIZER  
COVID -19 vaccine, also known as COMIRNATY® IVR & Live Operator Script Greetings   
PP-CVV -USA-0426  
877-829-2619 (877-VAX -CO19)  
PP-CVV-USA -0426_Pfizer -BioNTech  Covid -19 Vaccine  also known  as Comirnaty_IVR  and Live Operator  Script_Greetings  Page 6 of 8 
Confidential  Pfizer  document  - for internal  use only.  
Reproduction  and/or  distr bution  of this document  for any purpose  without express  written  consent  from Pfizer  is prohibited.   
 days following receipt of the second dose of the vaccine. The chance of 
having this occur is very low. You should seek medical attention right away if 
you have any of the following symptoms after receiving the vaccine:  
• chest pain 
• shortness of breath 
• feelings of having a fast -beating, fluttering, or pounding heart  
 
• Side effects that have been reported with the vaccine include:  
• severe allergic reactions; non-severe allergic reactions such as rash, 
itching, hives, or swelling of the face; myocarditis (inflammation of the 
heart muscle); pericarditis (inflammation of the lining outside the 
heart); injection site pain; tiredness; headache; muscle pain; chills; 
joint pain; fever; injection site swelling; injection site redness; nausea; 
feeling unwell; swollen lymph nodes (lymphadenopathy); decreased 
appetite; diarrhea; vomiting; arm pain; fainting in association with 
injection of the vaccine  
 
• These may not be all the possible side effects of the vaccine. Serious and unexpected side effects may occur. The possible side effects of the vaccine are still being studied in clinical trials. Call the vaccination provider or your healthcare provider if  you have any side effects that bother you or do not go 
away  
 
Data on administration of this vaccine at the same time as other vaccines have not yet 
been submitted to FDA. If you are considering receiving this vaccine with other vaccines, discuss your options with your healthcare provider.  
 
Patients should always ask their healthcare providers for medical advice about adverse events. Report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and 
Prevention (CDC). Visit 
http://www.vaers.hhs.gov or call 1 ‑800 ‑822 ‑7967. In addit ion, you can report side 
effects to Pfizer Inc. at www.pfizersafetyreporting.com or by calling 1-800-438-1985.  
 For the most recent full Prescribing Information (16 + years of age), EUA Fact Sheet 
for Vaccination Providers (12+ years of age) , and Recipients and Caregivers Fact 
Sheet (12 + years of age) please visit www.Comirnaty.com
  
 
PP-CVV -USA -0426- 02 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
FDA-CBER-2021-5683-0951798
 
  
Name  Capture  
7.0 
 
Address  Capture  
8.0 
 
Phone Number  
Capture  
9.0 
FAQs  are at the bottom  of the script  and noted  as HCP  or Consumer  FAQs  
HCP FAQs  
Access  
Administration  
Storage  and Stability  
Diluent  
Dry Ice  
Shipping Container  
Additional  FAQs  
 
CONSUMER  FAQs  
Access  
Additional  FAQs  
 
NOTE:  Agents  will follow  directions  in FAQs  for transfers  and reading  the ISI where  noted.   
 
 
Warm Transfer  
Pfizer DSU  
Pfizer  MI 
Pfizer  Trade   
ISI 
HCP  12.5 
Consumer 13.0  
 
  
 
Callers  come in  from:  
IVR 
Pfizer Trade  
First  Connect  
 
 
 
 
Welcome     
1.0 
 
 
  
 
  
 
  
 
  
  
Privacy  Statement  
6.0 PFIZER  
Pfizer -BioNTech COVID -19 Vaccine IVR Script  
PP-CVV-USA- 0303  
877-829-2619  (877-VAX-CO19)  
Previous  Caller  
4.0 YES 
Additional  
Questions  
12.0  NO  
FAQs  
HCP  10.0 
Consumer 11.0  
Phone Number  
Lookup  
5.0  
Caller  Type  
3.0 
 
YES 
HCP  Closing  14.0  
Consumer 15.0  
 
AE PQC MI   
Acknowledgement  
2.0 NO 
FDA-CBER-2021-5683-0951799
 
 Recipients  
Care Givers 
Fact Sheet  
10.5   
FAQs  
9.01  Operator/Failure  
Operator Business Hours 13.0  
Operator  Outside  Business  Hours  13.5 
Failure  Business  Hours 14.0 
Failure  Outside  Business Hours  14.5  
 
     
 
 
877- 829-2619 (877 -VAX-CO19)  
OR 
Transfer  from  Pfizer  Trade  
 
   
 
Transfer  to Pfizer  
Drug  Safety  Welcome  
1.0 From  Main  Number  
1.1 From  Pfizer  Trade  Canada  Customer  
Service  
     
 
Caller Type     
1.5 
     
 
 
Consumer  
Main Menu 
2.5 Failure  
Failure  Closing  15.0  
HCP Main  
Menu 
2.0 
 
      
 
   
 
 
        
 
 
 
      
 Operator/Failure  
Operator Business Hours 11.0  
Operator  Outside  Business  Hours  11.5 
Failure  Business  Hours 12.0 
Failure  Outside  Business Hours  12.5 Questions  
FAQs  
9.0 Container  
FAQs  
8.0 Dry Ice  
FAQs  
7.0 Diluent  
FAQs  
6.0 Storage  
FAQs  
5.0 Administration  
FAQs  
4.0  
Access  FAQs  
3.0 Recipients  
Care  Givers  
Fact Sheet  
10.5  HCP 
Fact  Sheet  
10.0  PFIZER  
Pfizer -BioNTech COVID -19 Vaccine IVR Script  
PP-CVV-USA- 0304  
877-829-2619  (877-VAX-CO19)  
 
HCP  
Consumer  
FDA-CBER-2021-5683-0951800