49 BLA 125742 0 08 06 2021 Letter UNII Code Notificat

Pfizer Documents (PHMPT/FDA)

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FDA-CBER-2021-5683-1150219
 
U.S. Food  & Drug  Administration  
10903 New  Hampshire  Avenue  
Silver  Spring,  MD 20993 
w ww.fda.gov   
Our STN:  BL 125742/0  UNIQUE INGREDIENT IDENTIFIER 
 (UNII) CODE ASSIGNMENT  
 August 6, 2021 
BioNTech Manufacturing GmbH  
Attention:  Elisa Harkins   
Pfizer Inc.  
500 Arcola Road 
Collegeville , PA  19426  
 
Dear Ms. Harkins : 
 The Food and Drug Administration Amendments Act of 2007 (Pub. L. No. 110-85) 
(FDAAA) requires that establishment registration and drug listing be accomplished 
electronically.  To facilitate your electronic establishment registration and drug listing 
process, we have assigned Unique Ingredient Identifier  (UNII) codes for  your product , 
COVID -19 Vaccine,  mRNA . 
 Active Ingredient/Active Moiety/ Basis of Strength:        UNII:  
BNT162b2 drug substance      5085ZFP6SJ  
 Excipients :          UNII:  
ALC-0159        PJH39UMU6H    
ALC-0315         AVX8DX713V    
POTASSIUM CHLORIDE       660YQ98I10   
MONOBASIC POTASSIUM PHOSPHATE    4J9FJ0HL51  
SODIUM CHLORIDE       451W47IQ8X    
SODIUM PHO SPHATE, DIBASIC, UNSPECIFIED FORM  GR686LBA74   
SUCROSE         C151H8M554   
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE  043IPI2M0K    
CHOLESTEROL        97C5T2UQ7J  
WATER         059QF0KO0R  
 Please be aware that your UNII codes  and substance name have been published on 
our Structured Product Labeling Resources website at https://www.fda.gov/industry/fda-
resources -data-standards/structured-product -labeling-resources .  If you need to contact 
us, please refer to BL 125742/0. 
 UNI
I codes  are a part of the joint United States Pharmacopeia (USP)/FDA Substance 
Registration System (SRS), which has been designed to support healt h information 
technology initiatives by providing unique identifiers for substances in drugs, biologics, foods, and devices based on molecular structure and/or descriptive information.   
 
FDA-CBER-2021-5683-1150220
Page 2 – STN BL 125742/0 – Elisa Harkins  
 These names and identifiers are accessible through the USP website at 
http://www.usp.org  and U SP publications, the Data Standards Council website at 
https://www.fda.gov/indus try/fda -resources -data-standards/fda-data-standards -council  
and the NCI Thesaurus website at http://evs.nci.nih.gov . 
 
If you have any questions, please contact me  at 301-796-2640 or 
[email protected] . 
  
Sincerely , 
 
 
  CAPT Mike Smith, Ph.D. 
Regulatory Project Manager  
Division of Vaccines and  
  Related Product Applications  
Office of Vaccines  
  Research and Review  
Center for Biologics  
  Evaluation and Research 
FDA-CBER-2021-5683-1150221