congress.gov News Web Result

Oversight of Gain-of-Function Research with Pathogens: Issues for Congress | Congress.gov | Library of Congress

The term gain of function (GOF) refers to any genetic mutation in an organism that confers a new or enhanced ability. Such changes often occur naturally. Additionally, scientists can induce such changes to organisms through experimentation.

Read article → AI? https://www.congress.gov/crs-product/R47114 2025-07-01

sciencedaily.com News Web Result

Scientists discover gene that helps the brain repair itself | ScienceDaily

These metabolites support the growth and maturation of oligodendrocytes, which in turn helps rebuild the myelin sheath. When researchers administered ATDR to mice with an MS-like condition, the animals showed reduced disease severity and improved motor function.

Read article → AI? https://www.sciencedaily.com/releases/2026/04/260415043630.htm 2026-08-10

brownstone.org News Web Result

What Good Comes from Gain-of-Function? - Brownstone Institute

Sep 14, 2026 · The simple definition of gain-of-function research is the introduction of a mutation that enhances a gene’s function or property—a process used commonly in genetic, biologic, and microbiologic research.”

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news.northeastern.edu News Web Result

What is ‘gain of function’? Why scientists are divided about the risk and benefits of experimenting with deadly viruses

The idea is to better comprehend what a virus looks like so that scientists can respond with therapies, vaccines or even further genetic manipulation to deprive it of a dangerous function, Auclair says. “You understand what a gain of function mutation might do, and how we might prevent it,” he says.

Read article → AI? https://news.northeastern.edu/2025/01/30/what-is-gain-of-function/ 2025-02-03

cidrap.umn.edu News Web Result

Feds shut down ‘dangerous’ gain-of-function research, tighten oversight of foreign collaboration | CIDRAP

Gain-of-function research is the study of infectious agents or toxins that are altered to increase their ability to cause disease, transmissibility, or host range to help scientists attempt to predict viral evolution, design vaccines, and develop effective countermeasures should an outbreak nationally occur.

Read article → AI? https://www.cidrap.umn.edu/dual-use-research/feds-shut-down-dangerous-gain-funct... 2026-07-29

news-medical.net News Web Result

What is Gain-of-Function Research? - News-Medical

Gain-of-function research (GOFR) refers to the serial passaging of microorganisms to increase their transmissibility, virulence, immunogenicity, and host tropism by applying selective pressure to a culture.

Read article → AI? https://www.news-medical.net/health/What-is-Gain-of-Function-Research.aspx 2022-09-05

bakerinstitute.org News Web Result

Gain-of-Function Research Is Vital to US Innovation | Baker Institute

Gain-of-function research is an important tool in medicine and other areas that leads to new biotechnologies, therapies, and tools. Instead of banning it, existing oversight can be used to ensure its safety.

Read article → AI? https://www.bakerinstitute.org/research/gain-function-research-vital-us-innovati... 2024-10-25

virology.ws News Web Result

Gain of function research explained | Virology Blog

Sep 9, 2021 ... Gain of function (GoF) research gives an organism a new property or enhances an existing one. The organism can be a virus, bacterium, fungus, ...

Read article → AI? https://virology.ws/2021/09/09/gain-of-function-explained/ 2021-09-09

sciencedirect.com News Web Result

Gain-of-function research - ScienceDirect

The term Gain-of-Function (GoF) describes the gain of new functions by organisms through genetic changes, which can naturally occur or by experimental…

Read article → AI? https://www.sciencedirect.com/science/chapter/bookseries/abs/pii/S00652164220001... 2022-07-13

bigthink.com News Web Result

The truth about banning "dangerous gain-of-function" research - Big Think

If the virus originated naturally, with parts of it found in animals that were located in a wild population in Laos, which genetic sequencing uncovered in 2021 indicates, the lab leak hypothesis is ruled out as a possibility. You cannot create something through gain-of-function research that will have an identical genetic code to something that came about in the wild through natural processes such as recombination.

Read article → AI? https://bigthink.com/starts-with-a-bang/truth-gain-of-function-research/ 2025-03-04

ncbi.nlm.nih.gov News Web Result

Gain-of-Function Research: Background and Alternatives - NCBI - NIH

In other words, any selection process involving an alteration of genotypes and their resulting phenotypes is considered a type of Gain-of-Function (GoF) ...

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sciencebasedmedicine.org News Web Result

"Gain of Function" Research Is Misunderstood - And That Is A Problem

Dec 4, 2025 · What Is Gain-of-Function Research? In the simplest terms, “gain of function” is a broad category of research that involves genetically altering an organism to give it new abilities or characteristics. In biomedical or other sciences, GoF studies have many purposes:

Read article → AI? https://sciencebasedmedicine.org/gain-of-function-research-is-misunderstood-and-...

asm.org News Web Result

PDF Gain of Function Research - American Society for Microbiology

of function.”) This may be accomplished in the lab by adding to or changing the organism’s genetic sequence, and this type of research has had a positive impact on basic and applied life science research. ... Outside of the lab, where microbes are facilitated by only natural selection in their respective environments, gain of function is a naturally occurring evolutionary process.

Read article → AI? https://asm.org/getmedia/24ebbde0-d618-4a8a-901c-6e297e6f92aa/hd-918-asm-gof-fac...

research.charlotte.edu News Web Result

Gain of Function (GoF) Q&A - Division of Research - UNC Charlotte

Gain-of-function (GOF) refers broadly to experimental techniques or natural processes that result in an organism acquiring new, or enhanced, biological traits. Life Sciences Research is research “pertaining to the study or use of living organisms, viruses, or their products, including all ...

Read article → AI? https://research.charlotte.edu/departments/office-of-research-protections-and-in... 2025-06-23

pmc.ncbi.nlm.nih.gov Pfizer Sponsored News Web Result

Gain-of-Function Research: Ethical Analysis - PMC

Gain-of-function (GOF) research involves experimentation that aims or is expected to (and/or, perhaps, actually does) increase the transmissibility and/or virulence of pathogens. Such research, when conducted by responsible scientists, usually aims ...

Read article → AI? https://pmc.ncbi.nlm.nih.gov/articles/PMC4996883/