At its core, an intelligent health system delivers value to individuals. By linking data across the full care continuum, it transforms how people understand and manage their health – enabling interventions that are tailored, equitable and preventive. Abu Dhabi’s experience shows how intelligence at scale can enable individuals to act early, protect their families and reduce the burden of disease across generations.3.4 Better health outcomes for individuals The Emirati Genome Programme (EGP) is a cornerstone of Abu Dhabi’s intelligent health system, turning genomic discovery into actionable prevention. By detecting hereditary risks at an early stage, the programme enables citizens to take proactive measures for themselves and their families while informing broader public-health strategies. This approach demonstrates how intelligence at scale bridges genetic insight and real-world impact across generations. Aisha Legge Aisha Legge’s experience illustrates how Abu Dhabi’s intelligent health system translates genomic insight into early intervention. Through the EGP’s advanced analytics, a hereditary ovarian- cancer mutation was identified before onset, allowing Aisha to undertake preventive care for herself and her family. Recognizing the value of early detection, she encouraged her children to participate, extending prevention across generations and building a culture of health literacy and shared responsibility. Community health impact Aisha’s story shows how an intelligent health system can transform individual genomic insight into collective benefit. By linking EGP findings to Abu Dhabi’s Population Health Intelligence Platform, patterns of hereditary risk are detected at scale, informing community screening and policy decisions. This integration reduces future disease burden and institutionalizes a culture of prevention across the population.CASE STUDY 4 Personalized preventionThe Emirati Genome Programme is a powerful tool in identifying patients and families at risk. By addressing these risks early, we shift the focus from treatment to prevention, ultimately improving outcomes and saving lives. Stephen Grobmyer, Chair, Cancer Institute, Cleveland Clinic Abu Dhabi Emirati Genome Programme BOX 5 The Emirati Genome Programme (EGP) is one of the world’s largest national genomic initiatives. With more than 850,000 genomes sequenced,28 it addresses the historic under-representation of Arab populations in global datasets, building a foundation for inclusive precision medicine. By integrating genomic data within Abu Dhabi’s intelligent health system, the programme accelerates rare-disease discovery, early diagnosis and pharmacogenomic research, transforming prevention into a measurable national capability. Scaled genomic sequencing is a public health necessity. We see population-wide sequencing as the foundation for a new model of care, one that, when combined with clinical records and artificial intelligence, shifts health systems from reactive treatment to precise, preventative and predictive care that is accessible. When nations sequence at scale, they generate insights that unlock real clinical impact, forming the backbone of a healthier, more resilient global future for all. Dimitris Moulavasilis, Group Chief Executive Officer, M42 A New Era for Digital Health: Abu Dhabi’s Leap to Health Intelligence 23

A New Era for Digital Health 2026