Technology Convergence Report 2025

Precision bio-production From personalized medicine to programmable cells and food systems, precision bio-production employs engineering biology technologies, including enzyme and molecule engineering, AI-driven predictive modelling and digital twins, to create tailored materials, molecules and biological systems. One outcome of this combination is precision biomedicine, which evolves the approach to individualized proactive diagnosis, treatment and prevention. These applications integrate patient-specific data, genomics and clinical information, with AI tools processing these multi-layered datasets to reveal how biological systems interact and influence outcomes. Another outcome is in enzymatic and molecular- level manufacturing, where enzymes function as programmable, modular components within a dynamic bio-production stack to custom-made biomanufacturing products. What makes this combination particularly powerful is its ability to create self-sustaining, adaptive bio products that can evolve and respond to changing environmental conditions. 3 3 3 22 3 4 32 4Precision bio- productionLLMs Domain-specific models Supervised learning Computer vision Smart drug delivery systemsBiocompatible materialsBioinformatics Biocomputing Biosensors CRISPR systemsTechnology domain Engineering biology Artificial intelligence Advanced materials Maturity level 3 Product4 Commodity 1 Genesis2 Custom-builtN This combination highlights how precision bio- systems are transforming the delivery of engineering biology solutions, making them increasingly personalized and tailored to specific needs. These advancements cut across industry value chains, from healthcare to agriculture and energy. Industry Company Outcomes HealthcareMerckAI-driven drug formulation enables personalized treatments, scaling research, analyzing unprecedented data and improving the health of every patient. AgricultureDSM- FirmenichDSM-Firmenich uses their AI platform to optimize microbial culture innovation for improved crop resilience and an expanded product offering. EnergyCemvitaSynthetic biology produces biofuel for low-carbon feedstock creation, streamlined processing and an accelerated energy transition towards a carbon-neutral future. Technology Convergence Report 26