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Cancer Case Studies Using Ozone and IVC Protocol
YouTube video by Dr. Frank Shallenberger (https://www.youtube.com/watch?v=x5wOX4NSb90). Transcript is the auto-caption track — verbatim ASR, not a certified transcript.
[Music] like to bring Frank back up and he has uh put together cancer case studies using ozone and the IVC protocol and immediately following that I'll have Dr. Celely come up and we will embark. I've got already about 10 questions up here and so if you're thinking of questions, now is a good time to write them out and bring them up and we'll we'll address them u in the Q&A session immediately following Frank's uh case presentation. So, thank you Frank. Thanks. What did I do with the pointer? I got it. I got it. Okay. All right. So, um I just, you know, I want to kind of see what I got here. Okay, I got you. Okay. So, I'm just going to kind of explain a little bit about um what I'm doing and uh and then we'll see what happens with the Okay. So, uh, some of the stuff you're going to probably could answer by now. How do oxidation therapies act to decrease, um, to reverse the decrease in oxygen utilization? Okay, so let's talk a little bit about the difference between an oxidation therapy and oxygenation therapy. They're similar. They have some overlap, but they're actually different in concept. An oxygenation therapy is where you provide more oxygen to the tissue. That's not what you do with oxidation. Like I've heard I've heard critics say, well, your ozone can't possibly work because the amount of ozone that you're amount of oxygen you're giving in an ozone treatment is less than the amount of oxygen you get in a half a breath. So that couldn't be work. And they're absolutely right. But that they're thinking of it's like being a supplier of oxygen. It's not. Oxidation is a different deal. oxygenation therapies or would be like an EWAT therapy, an exercising with oxygen therapy where you've got a mask on and you're you're inhaling oxygen at 100% and you're exercising so you're getting a greater delivery to oxygen to tissues or hyperbaric oxygen that'd be an oxygenation therapy. just just regular aerobic training uh uh can be an oxygen oxygenation therapy assuming you don't get anorobic in your training at that point it becomes an oxidation therapy uh simp it basically just delivers more oxygen to the areas that are deprived of it does not directly decrease reverse decrease oxygen utilization indirectly it can because let's face it if you have an area that isn't getting enough oxygen it's going to have low oxygen utilization By definition, uh if if you have uh if one of your problems is endothelial in origin and your endothelial cells are all swollen up, so your capillary diameter is effectively decreased. You can't deliver blood to the area, i.e. you can't get oxygen to the area. You can reverse that with oxygenation therapies. So they do tie in. So there would be a place to to have somebody do an oxygenation therapy and tag it onto an oxidation therapy. There's a place for that and you could give easily and I would recommend this if you do HBO I would recommend that you prior to the HBO you give your patient an ozone treatment then put them in the chamber. Uh that said they are different. Oxidation therapies do not provide more oxygen. That's not what they're about. Instead they they do one thing basically at least in my mind. um uh in terms of oxygen metabolism and how they do other things too but but uh they basically change the ratio the NAD to NADH ratio. They're going to oxidize the NADH back to NAD. So kinds of oxidation therapies would be interval training. So interval training is where you um you're exercising and you're sort of warming up and then you go at a pace that you could not possibly sustain. You go at a pace where after about two minutes, three minutes, um, you're you're in a state of complete anorobic metabolism. You hurt, you're dizzy, you're a little nauseated, you're queasy, you don't feel so good, your heart's pounding, you're way short of breath, and you're thinking to yourself, I pretty much hate this. Now, you're doing interval training. What you've just done is you've put yourselves your cells in a state of oxygen deprivation. they can't keep up what you're making them do. And as you do that repetitively, short bursts, if you do a really long burst, you just kill yourselves. I'll tell you an interesting story in a second, but uh you do a short burst of it. So, just a little bit of that. And if as you do that over time, what's going to happen is your cells are going to upregulate the way they use oxygen. They're going to improve in the way they use oxygen because you're demanding that adaptation from them. Um, however, you can't do it too much. So, so I'll tell you a story. I have um I have a number of uh patients who are uh like they run marathons or triathlons, things like that. And uh of course, if when you measure their oxygen utilization, off the charts good, that figures. Uh anybody with lousy oxygen utilization isn't going to be doing that for starters and won't be able to do that. But these guys look great. But a few times they've come to see me and I've checked their and they usually typically see me once a year for this. And they come to see me and I'll check their oxygen utilization. It's in the tank. Totally in the tank. Guess what they did? They just ran a marathon about three days before. They destroyed their mitochondria. Flat out destroyed it. Okay? And uh and so what do I tell them in each case? Don't train. Don't do anything. I want you sleeping and eating and that's it. They come back in two weeks. I recheck them. They're right back to their former glory. Okay. It's pretty sobering when you see that happen. Uh and so that you can realize that one of one of the things you don't want to do is overtrain. How many people in here are guilty of possibly overtraining? There's one back there. Okay. Mostly we're guilty of undertraining. But there are these kinds of people out there that will push themselves and then you'll see these patients. They'll come in and they'll I've had world class athletes or at least nationally ranked athletes uh come in with s who are sick with chronic fatigue syndrome. How they get that way? They got that way because they didn't get enough rest period for the mitochondria to recover. So when you do interval training, you basically do it for maybe two minutes and then you go into almost nothing mode for about four or five minutes. Let everything recover, settle down. all the free radicals are cleared out, all the acids cleared out, blah blah blah, and then you feel pretty good, and bang, you go hit it again. And you don't do it too often. You maybe do maybe do three maximum five intervals at a session. But that would be an that would be a really good oxidation therapy for you guys to get into some interval training. I would suggest three to five, two-minute intervals, three times a week. It'd be pretty nice. I see some good improvement with that. Introvenous hydrogen peroxide is a great way to go. Uh I like ozone because ozone has so many in a general medical practice which is what I have. You can use it in virtually every patient you see for anything from low back pain to dental infections to Lyme disease to cancer. I mean it's got the applications of it are huge. Hydrogen peroxide applications are much more narrow. Uh but from a systemic perspective hydrogen peroxide can be very very helpful. uh EDTA EDTA chilation therapy due to its effect on uh iron uh iron feric to ferish ratios is is it has a certain oxidation aspect to it so that you can tag all these things together and I know a lot of docs will put put combine the chelation with either ozone like I do or with hydrogen peroxide you can tag them together um ultraviolet light uh blood radiation typically is an oxidation therapy chemotherapy radiation therapy obviously are oxidation therapies. Uh vitamin C and the high dose in a sense is an oxidation therapy isn't it? So uh uh in the issue about uh can you mix vitamin C with oxidation therapies? You know in the ozone world this has been actually a no no for many many many many years. Everybody thought if you mix the two, uh, you one's going to cancel the other. And I have to say I was a complete believer in that just because everybody told it to me. I never tested it out. Nobody, by the way, has ever tested it out. It's just one of those little myths. It's handed down because it makes sort of sense, right? Uh, that, you know, an antioxidant therapy would antagonize an oxidant therapy. That makes sense. It's not the way it works, though. Over the last year or two, we have uh due due to anecdotal reports that I've gotten from other physicians and some of the reports we've been getting out of the academy at the an annual meetings. Uh I have now been combining uh highdose vitamin C with ozone therapy. Uh I've been combining um Oh yeah. And I and I also like highdose oral vitamin C with ozone therapy and it works great. They work great tag team right on another. I'll give somebody uh you know 100 grams of vitamin C and right after that give them an ozone. I'll give glutathione. That's another one. Glutathione is a potent antioxidant and we see dramatic results uh administering ozone for about 30 minutes then giving them a bolus of say thousand milligrams of glutathione then another 30 minutes of ozone. We see with my Lyme disease patients I have to tell you it's almost a slam dunk. Um, so you think they counteract each other, but they don't. So, uh, I'm I'm telling people, listen, you no, not only no longer don't h have to tell your patients, don't take any vitamin C on the day of your therapy. In fact, you should tell your patients to do that. There is a synergism there. And I hope to maybe explain what's going on. I have a theory about what's going on there a little bit later. I'll go get into that. Uh, ozone forms peroxide. So you know the thing is that um when you inject ozone into a body cavity or into blood or whatever method that you're using uh it instantaneously in nanconds reacts with lipids. It finds double bonds. It wants it wants to uh give away its electrons and dismutate itself. So it instantaneously reacts with double bonds. So when we inject ozone, for example, into blood that's in a bag, uh the systemic way you usually do it is you pull blood out into a bag and then you inject the gas. Ozone is a gas into the bag and uh it interacts with the blood instantaneously. Uh there's no more ozone in that bag. Okay? What's in that bag now is peroxides. So basically, it's a peroxide treatment. When you stop, think about it. When you inject ozone into the rectum, 30 seconds later, there's no more ozone in the rectum. It's just oxygen. All you have in the rectum now is peroxides in the rectal mucosa. Now these peroxides promugate they move and uh so they do have systemic uh activities to them. When you put a patient in an ozone sauna you make peroxides in the skin. If you give them ozonated water you got peroxides going in the GI tract and so forth and so on. So the ozone reacts with the double bonds in the lipids and all the double bonds. Okay? So it really breaks them down into very short chain peroxides. These are little small molecules. These molecules can literally go through membranes and so uh and and they last a long time. So the ozenides are shortchained. They can penetrate membranes easily. Um they're stable for a long time. So after you give an ozone treatment, you know, you still got these uh these peroxides around for at least a week. You can measure them if you want. just do a serum lipid peroxide level and you'll see they go up. Um, they're selective reactive. I think what they do, and there's some good evidence to this, what they do is they get into the cells and they oxidize the NADH in people that have an NAD to NADH ratio. Now, what do they do in people that already have a good NADA ratio? Nothing. They don't do anything. We've seen this. We've we've studied this where we'll take somebody that's got a already has good mitochondrial function, give them an ozone therapy, nothing happens. So, if you're already in great shape, you're not going to benefit by giving yourself ozone, I don't believe. But if you're not in great shape, that's the way to do it. Uh, this just shows there's your double bond. There's the ozone interacting, licing the double bond, producing the peroxide. There's zillions of these peroxides. Nobody knows how to catalog them. They just call them ozonides and they do all kinds of things. Most of them are in cell membranes, right? So, uh they're in the red cell membranes and in the white cell membranes and no matter where you inject, if you're injecting a bladder or whatever, it's going to hit hit membranes and start inducing intracellular changes. Uh basically, just to reiterate, there's your ozenite that we just made. It interacts to produce the NAD. also get a little oxygen bust, but that's that's not really what's happening. Okay. So, you could also say that oxidation therapies are going to be enhanced with certain things. They don't work in a vacuum, do they? Uh so, so the NAD has to have something to work on. It's got to have some carnitine there. Okay. So, uh so there are certain things that can help with this. One thing that would be really obvious would be nascin. And so uh we find out that a lot of times uh if you just give your patients you know five to 10 uh 10 thousand uh uh five to 500 to 1,000 milligrams of niacin a day marvelous stuff starts to happen and it can it can combine very nicely with ozone. The other the other intermediate I didn't mention is a riboflavin intermediate that's FAD. Uh so riboflavin seems to be valuable. Then anything has to do with methylation remember they're one-on-one. So uh anything to do with methylation can be very helpful. You can actually even give oral NAD and we do this. You give oral NAD. You can give it introvenously. I suppose I just haven't done that. And so now you got NAD in the bloodstream because you just gave it orally or introvenously. You peroxides are going to what they're going to do to that NADH that's in the bloodstream immediately form NAD out of it. Um, so does it really work in the real world? Uh, I presented a lot of theory to you guys, but you know, unfortunately, we don't have a lot of indisputable hardcore data. I will mention to you, by the way, though, if you go to the academy website, uh, it's a aot. American Academy ozone therapy. AaOT us. You can access a library there for free. You don't have to be a member. You can access a library there that'll get you can search over about anywhere from four to 5,000 different published studies over the last 50 years through that library. You can just plug in psoriasis and you'll get any study of anybody's published on ozone psoriasis for example. Um that said uh you know how do we know this theory actually works? Well, this was an interesting paper that uh came out a few years ago and it is called pharmacological stimulation of ad NADH oxidation. It's what we're talking about. Ameliorates obesity and related phenotypes in mice. So the authors point out that the NADNADH ratio quote plays a crucial role in cellular energy metabolism and the disregulated ratio in other words decreased ratios is implicated in metabolic syndrome. I'm flat out here to tell you that's what causes it. That's your cause of all the diabetes we got going on around here. So they use a substance called beta lapone. They didn't use ozone. Same idea though. And beta lapone oxidizes NADH. And they did this in diet induced obesity mice. And the conclusion was uh that the NADH oxidation strongly provoked mitochondrial fatty acid oxidation in vitro and in vivo and dramatically am ameliorated the key symptoms such as increased atyposity, glucose intolerance, dysipidemia, fatty liver. I mean is this like common? This seem like what we see all day long half the time. Uh this is good though. Then uh it says the treated mice also showed higher expressions of the genes related to mitochondrial energy metabolism. We shouldn't be too shocked like sir 21 uh uh consistent with increased mitochondrial biogenesis. It actually makes you make more mitochondria. uh and the conclusions were that the pharmacological activation of NADH by oxidation by that betalapone resolves obesity and related phenotypes in mice opening the possibility that may provide the basis for new therapies and so forth so on but you know in in a in if I were president uh everybody that's overweight would go in and get an ozone treatment every day until they weren't overweight anymore they'd probably get some dietary advice while while we were at it um Okay, another take-home message. It's uncommon that ozone therapy will successfully treat a patient as a standalone therapy. I do not believe it's a standalone therapy. You really have to integrate it. I've had patients that come to my workshops and and they go home and then they call not patients but doctors they go they call me back like three months later says I'm not getting results like you. I said what are you doing? Well, I'm giving the ozone therapy. What else are you doing? Oh, nothing. You're not giving them thyroid. No, you're not getting any B vitamins. No, you're not putting them on low carb diet. No. So, it needs to be combined. So, here's the point. Whatever your thing is, whether you're an acupuncturist or you're into detoxification or whatever your deal is, ozone will augment what you're doing. You don't stop doing what you're doing. You just add this in. You got another bullet in your chamber. Okay. So, how's it helpful for cancer in in my world? Uh, I don't know how you guys are like I only get the worst cases. Is that like this is a wrong thing. This is wrong. I'll tell you a funny story. We had had a little autistic kid. Cutest little kid you ever saw. His name is Stevie. He's got the big horn room glasses. He's about seven years old and just cuter than heck. And u his mother says, "I want to give him some ozone therapy." I said, "Well, you know, it's it should work. It's there's a mitochondrial issue here and there's certainly a detoxification issue and and uh you know we know that ozone especially when you give it rectily intensifies the um the P450 uh detoxification systems in the liver and which autistic kids they don't do that. So let's let's give him a little rectal ozone. Now I was thinking to myself, I don't know if an autistic kid's going to buy that. Uh but anyhow, let's try it out. So I said, I also have a sauna. Let's see how he does in the sauna. So he goes in the sauna and he comes out of the sauna. I said, "Mom, how do you do?" He said, "Oh, he likes it in there." It was kind of funny because we had to give him a bunch of cushions and his head is just barely peeking out the top. And so then the next thing I know is we put him in the room. We give him a little rectal and I now hear Stevie standing there. This is not supposed to happen. That kid's a genius. Yeah, sounds really wrong with that. Sorry. Anyhow, um, so ozone therapy for cancer. Um, uh, so yeah. So, anyhow, I don't know how I got off on that, but, uh, I I get like the world's worst cancer cases. I mean, they're just god- aful horrible. Um, like not very many of them live through their cancer. Like maybe maybe one in 30 30 or something actually live through it. But up until the time they die, they have a really good quality of life. I mean, they probably only have it really bad for about two to four weeks. I mean, they're out riding their bike and then 30 days later they're dead. And that's so that's what I can tell you my experience has been. Um, we do IPs with them. We do vitamin C's um and we do a lot of detoxification all you know that so the whole approach that the first speaker was a bit talking about um so what's the ozone how's the ozone therapy helping for for one we we know studies show that it increases antioxidant enzyme activity in healthy cells the healthy cells here's the thing if you um if if you give an individual who has poor antioxidant uh activity and in other words excessive of uh oxidant stress and you give him a bunch of vitamin C or antioxidants. Are you fixing him? Not really. Okay. You're band-aiding him. Is a guy with a headache and you're giving him aspirin. Long as you give them aspirin, the headache's not there. Take the aspirin away, he's in the same mess. Because what these substances do is they back up the enzymes. They back up the catalase and the glutathione peroxidase. The enzymes are what actually do the oxidant control. So if you don't have the enzymes, you got a problem. Yeah, you can make up for that problem by dumping in a lot of vitamin C. It's true. As soon as you take the vitamin C away, you're back in the same bag. Unless somehow at the same time, you've upregulated their enzymes. And that's what ozone therapy. That's what oxidation therapies do. They upregulate the enzymes. In the in the course, I show slides after slide where you can see this definitely happening. Glutathione peroxidase goes up, catalase goes up, SOD goes up, all of them go up after oxidation therapies. And in patients, so I have a lot of patients that come in and I measure these things on them and they're low and they've been on high mega doses of antioxidants for years and they still have low enzymes. It doesn't fix anything. But you throw the ozone in combination with that, now you got something going. So it works great with the antioxidants and actually makes them work better and and in that way it protects against so many of the side effects because most of the side if not all the side effects of radiation and chemo due to its oxidant stress on healthy cells. Uh it increases the chemo radiation efficacy. So we the previous speaker alluded to that along with vitamin C by adding additional oxidant stress. Uh my patients come in, my nurse for a while there um worked at the local hospital over in the chemo center for about two months. That's about as long as uh she lasted. And uh she said she said, "You can't believe it. I go over there and they look like a bunch of zombies and they're all dying and people over here are like, you know, reading their books and chitchatting and so forth and so on. And you know, after they get their treatment, they go out. My office is right on a golf course and they go right out and play golf and and you know it's just a world of difference. So these these people you most of them you wouldn't even know had cancer even though they have serious advanced disease. It induces anti-cancer enzymes. So the the studies clearly show the TNF alpha interferon gamma interlucan 2 all stimulated by ozone therapy. Um it directly direct contact kills cancer cells. So, I've had cases where they have a non-penetrating bladder lesion and we just shoot ozone in the bladder and that's the end of that. Had a few cases of anal carcinoma uh which were ear early discovered that we just shoot ozone into the rectum and that takes care of that. So, if you can get it right on the cancer cells, you can get rid rid of the cancer. Uh but mostly it's a systemic treatment. Uh it can normalize marginal cancer cells. So if you we have this concept of marginal cancer cells again these are the cells that we were previously talking about that are about ready to move over in that direction but haven't quite made the move. It can prevent them from going in that direction and it stimulates apoptosis. So everything I just told you there if you were to go to the course I'd be showing you studies that back me up on that. Um lots How we doing time wise about five minutes. Okay let me see what I got here. All right. So, I Okay, maybe we can squeeze a little bit more out. Uh, different ways of doing it. You The most common way is you pull blood out into a bottle or bag, inject ozone gas in there. The ozone inter interacts immediately with the white cells and the red cells in the bag, creating all these peroxides and inducing cytoines and everything. So, you got this sort of activated blood, if you will. Then you run that back into the patient. Um, you can also put it in put it any place. We have an opthalmologist in the academy that's injecting it into the eyeball. I haven't done that yet, but anyhow, you can put it any place. If you get the dose down, it's entirely safe. You can put it in any place. So, in the intestines, in the vagina, bladder, stomach. I had a patient that was uh what was that? Uh gosh darn it, gastroparesis. So, a severe case of gastroparesis in the hospital, came out of the hospital into my clinic with an NG tube in place. I said, "What the heck?" I took uh some uh syringes of ozone gas and injected right down the NG tube into the stomach. Ozone gas into the stomach. I thought, "I've never done this before. It's got to be fun." So, I just I shot in maybe 500 cc's of gas into his stomach. Um he started burping. I started pulling gas out and stuff like that. Guess what happened to gastroparesis? Gone. Pretty amazing. So, you can put in anything any place you want except lungs. Can't put in lungs. Uh so when you see that thing down there says lung inhalation that means that's a different sort of deal. You the lung inhalation thing is you bubble the ozone gas up through olive oil. Turppen are formed. It interacts with the olive oil to form vaporized turppen and then you inhale those turppines. Now that's a whole another deal. Um but that's the only place you can't put it. You can put in ears. We we for metastatic pancreatic carcinoma we'll put it right into a parinal cavity. So I'll have an indwelling caparit parinal tube especially if they get continual parinal um uh uh if they get continuous and we'll pull the fluid out through there and shoot some ozone in there and that can be very helpful. Uh you can put it around tumors, put it right into tumors. I don't think it works very well right in tumors. Uh you can you can use oil that's been ozenated. You can put the oil into body cavities. You can eat the oil. You can put it on teeth for periodontal periodontitis issues. You can ozenate saline and uh and then drip in the ozenated saline. You can give it by sauna. So there's lots of ways you can do it. I did want to before we go kind of uh you guys can tell me if I have this right or not, but I think this is sort of the deal. um that uh the the action of ascorbic acid is on the Fe3 and that produces the yeah okay so I'm right there so uh what happens is that the DHA then goes to uh stimulate collagen and so this would be one of the ways that uh uh in in a in a tumor that lacks catalace one of the ways that you would generate uh the hydroxal annion and kill the tumor so as I understand it that's the kind of way that can go. So, um this this is what I think might be happening with the ozenides is that the ozenides are actually producing more DHA and under the influence of lipoic acid. And what we typically do is we load the patient up with maybe 600 milligrams of oral lipoic acid about 60 minutes before an ozone treatment. And um so we think maybe this is what's going on. I don't I don't really know, but But I will tell you they're synergistic. There's no two ways about that. Let's see what I got here. Um, okay. So, just some real quick case studies. Uh, erectile adinoma carcinoma in C2 with high-grade dysplasia. 78-year-old female, 12-month history of rectal bleeding, difficulty passing stools, has 3 cm rectal mass, CA slightly up, 99 slightly up. uh give erectile ozone plus ultraviolet light two times a day. Two times a day. Okay. Uh uh and we do that four days a week for two weeks. Uh the mass is half size. The bleeding has stopped. This is typical. Now I might not cure this patient, but this is typical. Uh continued above for three more weeks. All the bleeding stopped. Stool is easy to pass. The mass has gone all the way down to 3 mm. At that point, we put some IP in there. And that patient did really well. 3 years later, uh, esophageal CA with METS. This was an amazing case. 68-year-old uh, guy uh, with a four-month history. He had he just absolutely refused any conventional treatment. He couldn't swallow. He's having constant hiccups. He got literally couldn't swallow his saliva. Um, we we just initiated the IP following by MAH. He did really really well in about um, a month or month and a half. the swelling is almost normal. His hiccups was gone. He started to feel good. Uh and uh you know two three months later the PET CT scan shows a 50% decrease in mass. We continued the treatments and u pet scan became absolutely normal. Couldn't find anything in him. About 2 three months after treatment he was eating and swallowing and he looked like the healthiest guy on the planet. He actually he lives in Alaska. He went up Alaska and started hauling in 400 lb halibits in his boat. Uh here's a 68-y old male diagnosed with squamous cell, pretty rough cancer. He had radiation at VA hospital. Uh oh yeah, this guy was good. So prior to each radiation session, we gave him hydrogen peroxide. So he gave him hydrogen peroxide, sent him right over for his radiation. So he had complete resolution of the cancer. This was like 10 years ago or something. Uh no recurrence. Um and so his doctor goes to him and says, "You know what, Fred? You have done so well with our treatments here that we want you to talk to the other patients and uh you know, and tell him how great things are here at the VA." And he says, "Yeah, I will, doc, but I got to tell you, I lied to you." He says, "What do you mean?" He says, "You said I I you know, I shouldn't get any more therapies, and I promised you that I wouldn't, but I did in fact get hydrogen peroxide before all the radiation treatments you gave me." And the doc's response was, "Oh, great. We'll tell all the patients that that you got the hydroxin that really are." Not exactly. Doctor's response was, "Uh, on second thought, maybe you better not talk to them." A 65year-old asymptomatic male with heepsi. Oh, this is a great case. So, this is a good case that exemplifies things. This guy just died about a month ago. Uh, when he first came in, though, uh, he was in deep. They give him like two months. This is like two years ago. Hepsi. Uh they started him on some saraphanib at the VA. Gave him a four-month prognosis. His uh alphatheta protein was 82. His enzymes were way high. We did the vitamin C every week. We gave him rectal ozone because those rectalone go straight to the liver. Uh and uh sure enough, a couple months later, his AFP is all the way up to 133. That's actually good. You know, getting some cancer die off. His enzymes are coming down. The MRI shows an increasing mass. I take that to be swelling. Uh and then the then the a the AFP starts going down and uh the last bullet there say patient remains asymptomatic fully functional. This is a year and a half later. His AFP is less than 30 and his liver function tests are normal and that's all he's getting folks is that he did really really really well until finally he didn't. But he had he had this guy was in good shape, working, having a life, doing his thing, going fishing for a solid two and a half years before he died. A 51 year Oh, this is another good exemplary case. So, here's a 51-year-old woman diagnosed in '07. Had the whole deal, the mastctomy, the radiation, the whole the whole thing. Uh, basically was a failure of conventional therapy. Bone mats, liver mats, weakness, anemia, just a massive disaster. just a beautiful woman, just a real little heartbreaker. Uh we started treatment on her. Sure enough, man, uh you know what she complained about a year and a half later? Uh her hip was hurting her. I thought, "Oh, you got a bony metastasis." She said, "No, I was riding my bike. I was on a mountain bike trail and I crashed it and hurt my hip." I mean, that's a year and a half after I first started seeing her. Uh ultimately, the disease started to progress and she declined. She went into liver failure and died in about two weeks. She went from riding her bike to dead in two weeks. She had a good uh two years or so out of that. Um okay, that's just the vitamin C stuff. You guys know about that. Okay. Uh colon cancer, 73 year old male with three-year history of recurrent CA. Also, diabetes, too. Infected foot, AIBs, cerosis. These are my people. These are my guys. Uh weakness, diarrhea four times a day. all kinds of medications lab unremarkable now that's remarkable that it's unremarkable so we did some IP um and um we also followed it with mAh uh and he did really well insulin insulin potentiation that's what I mean so it's a form of chemo you guys probably mostly know that it's a form of chemo where you do low lower dose and potentiate it with insulin uh and I think this might well I got two more do I have a little bit time still. Okay. So, a 78-y year fe uh female with 12-month history of rectal bleeding. Uh oh, yeah. This is wild. Uh she passed she had a palpable rectal mass. Um and you know what happened was uh after a while uh she passed a piece of plastic. uh she had had some sort of bladder repair operation and the doc left in some kind of piece of plastic in there and it went out of the surgical site down into the rectum formed an abscess. She got a cancer from that and the next thing we know we're in there I'm palpating her mass all the time and now comes this piece of plastic and when the piece of plastic came out everything healed up really nicely. Pretty crazy. Uh we were given we were putting oz on into her rectum all the time. Uh okay so 65 year old female post 12 months of ineffective alternative treatments. Um I don't know what she was getting. Uh fungating bleeding fixed breast mass. It was nasty looking. Uh she uh had a mastctomy on 610. All the margins were positive. In 910 she had pain and weakness. CA was 15. We started on IP. Each time she got the IP, she followed it with an MAH. That's the ozone treatment. We did an ultrasound of her liver a couple weeks a couple months later. Uh she was seeing a 50% response and her CA was down. She felt great. And that's the thing that of course I want to emphasize. Uh on 411, the PTCT showed dramatic improvement. Uh the treatments continued but decreased. We just started spacing them out more. And finally in uh July of 11, this is roughly a year later, um the wound haded healed up uh she had no residual disease on PT and then she went back home and uh uh didn't get any more therapy and then subsequently they found the brain mets and they did some radiation to her and then she died. So that's it. That just gives you a little taste of the little poperria of some cases that really had fabulous results. But in general, every one of my patients does really well. They have a life. Uh even right now, I'm treating a a lady that Jerry Taylor sent me that uh for the last I want to say year and a half, two years, has had a horrible situation with her cancer, but she's had a life. She doesn't have a problem. She gets up and she does. You'd never know there's anything wrong with her. She looks healthier than heck. Um, so there it is. Um, okay. So, thank you. [Applause] Before you go too far, Frank, excuse me, I just swallowed the wrong way. I have about five cards asking how you measure oxygen utilization and mitochondrial function. U, the best the best thing to do is to email me and I'll send you a lot of stuff I've written on it. Uh, so my email address is the word doctor and the domain is pretty easy. It's anti-agingmed.com. So doctor at anti-agingmed.com. Just tell me you want some info on that. Uh, the gist of it is this. R, no. Yeah, it's doctor spelled out d oct t- o r. Uh, the gist is of it is this. Um, uh, we use a pulmonary gas analyzer. So this is a piece of equipment. uh it's about yay big and uh you wear a mask and it's tracking your breath so it knows how much oxygen is disappearing into your body simultaneous to how much carbon dioxide is coming out of your body and again remember that's the definition of how efficiently you're processing the oxygen is the amount of CO2 coming out relative to the amount of O2 going in so we do that with the patient resting that gives me their basal metabolism and all their basal data and then I put them on a treadmill or an exerciser and we do that for about 15 20 minutes and we keep ramping them up. Uh uh and then we see how efficiently they do it under under an exertional load and based upon that we take that information run it through uh I have a patented uh algorithmic uh program that runs that through then gives you all the the data on the mitochondria and that's how we do it. simpler and heck, anybody can do it. Um, it the equipment is, uh, you know, it's not that much. It's like 15 grand for everything. Lights, buzzers, everything you want to do. Uh, there's there's actually codes for it. You can build Medicare for it if you so desire. Uh, and, uh, it's a very handy test. It's easy to do. I'll be glad to tell you more about it if you get any of my books. Uh so I have a book called Bursting with Energy and I have another one called the type two diabetes breakthrough. Um they're very similar but they both discuss this process uh to Several while you're here at the mic several uh questions regarding the legal status in various states and uh putting ozone therapy on your website. Does that is that a red flag or have you had any problems legally along that line? you know, uh that was that was more of an issue in years ago. We we don't typically see that. Uh we have uh uh doctors in in all 50 states that are using ozone therapy now. You know, they don't really go out of their way to push it in everybody's face, so to speak. Uh but um but they do use it. Uh most medical boards these days, you have to check with yours, but most medical boards these days will say, you know what, if you're giving your patient an informed consent about what you're doing, we're okay with it as long as you're not killing them. Um for those now, there are some people and like I think KY's a pretty rough spot. Uh I think Ohio might be a rough spot. Um there are some states that uh you don't even want them knowing what you're doing in that regard. Um what can be helpful for people that are in environments that are unhealthy in that way is that the academy has uh uh an institutional review board sponsored research project going on has been going on for about a year now. We have maybe 30 co-investigators on this. I'm the principal investigator. It's an ongoing project studying the cost effectiveness, efficacy and safety of ozone in its various forms of therapy. So, uh I do happen to know that a certain amount of our co-investigators are signed up for that uh uh that project. Uh pardon me. Yeah. Well, it's it's what happens when when you're doing research is that um uh that research is no longer um under the jurisdiction of your medical board. Okay? So, so the medical board says, you know, Dr. Shalom, I don't like the fact that you're giving ozone to the these patients and and your response is, "Yeah, well, this is part of a research project, so you don't have any jurisdiction on it." The FDA has jurisdiction on it, so they can come in and check out what you're doing. But as long as you're adhering to the protocols, this is all FDA approved. Basically, it's what the IRB does. And um uh so I know some doctors that are just doing that so that they don't have to fiddle with their medical board. But it's really nice for us because we get uh uh a lot of really interesting information. And one of the things about ozone therapy that's pretty neat is it's cheap. You know, vitamin C can cost you. Ozone therapy is cheap. And so what we can show is real cost effectiveness, especially with certain things like pain. Ozone, I didn't mention this, but ozone will take away pain. So for your for your cancer patients that have like bone pain or something like that, shoot some ozone in there. They don't have it anymore. And um so for so in terms of pain and other issues, ozone therapy is very cost effective and we're hoping to be able to publish data. Ultimately, my plan is within five years it'll be covered by Medicare. That's my plan. We've seen this happen in some of the European countries. So I don't think it's completely unrealistic. Just need some data on that. Uh but mostly you have to check with your medical board if you want to know what they're going to think about it. Yeah. Question for Dr. Cely. Uh what is the average cost of a patient to go through the research that you're doing? no. Okay, now it's on. Thank you. Um so for the cost would be uh our cost for for IV vitamin C for a patient would be is 165 Canadian which is roughly um a little bit less. American would be about 150 now I think. Uh and then the the the consultations with the naturopathic doctors those are about an hour and a half. The charge is 205. So patients are probably spending anywhere from I would say 350 on the low range um well for initiation per month uh up to maybe 1,500 per month and even potentially higher if they're doing all the therapies. Most people are spending probably about $400 a month. What's a typical 50 gram vitamin C infusion up in Canada? Uh about 150 to 185 per session. Okay. Thank you. Uh and then another question to you Dr. Cely. were asking uh using which which type of glucometer do you use or or either one of you could answer that question in terms of using the glucometer as a way of monitoring vitamin C to see if you're getting it up at least into the what we would consider a prooxidant therapeutic range and I don't know if there's a one type that you prefer. Uh we use the precision I got the question earlier I couldn't answer it but it's the precision uh ultra or not the precision ultra it's precision uh and then there's a precision ultra which does ketones as well although I've heard they're discontinuing production of those but that's what we use and it works it's been working effectively to get 350 to 400 range milligrams do you do that same thing Frank you use yeah I I I I don't know when we use either but exact I do the exact same thing you do with same measurements and everything 350 400 over baseline. Okay. Uh several questions about things that are added uh to IV vitamin C. Can you add ozone to meers? Uh or do you start running into the problem of of uh oxidizing certain nutrients or causing other side effects when you start putting a bunch of multiple nutrients in You would not want to take u say a bag with nutrients in it like vitamin C or B vitamins or anything really. You want to take that bag and shoot ozone into that bag. That makes no sense at all. You're just going to oxidize all the products in the bag. But you administer that bag to the patient. Now it's in their bloodstream. Okay? Then you take an aloquat of that blood. Now of course some of those nutrients are in that blood but how much? Very little. So you might be oxidizing them a little bit but but so you piggyback these things. So yeah we use all the time. So uh a typical for me would be patient comes in we we give them the vitamin C after the vitamin C we give them an ozone after an ozone we give them a meyers send them Does ozone therapy have any efficacy in H uh okay so I don't really have enough information on that. I've had a couple of cases and uh we've not done very well. I apply ozone oil to those cases and I think it's been helpful but it's not cleared it up. Uh Dr. Cely u are there any major objections to IVC that that this person was saying is there data or failure of treatment that we don't know about? I thought you covered that pretty well, but is your any thought any thoughts about um why you wouldn't want to do IV vitamin C other than the normal contraindications? Um really would be based on on cost and time for the patient. That's the major issue. And we're typically using IV vitamin C for more advanced cancer patients. Uh not so much for early stage. We're using other things like oral natural health products, maybe subcutaneous mistletoe. So we're not we're yeah the majority of the patients that are doing IVC are are advanced uh patients. So we have a question here about what strength of ozone do you use? So that's the kind of thing you want to go to the course for. So if you go to the course, we do a course uh in October. Uh it's already sold out. We do another one in in April. That one's about threequarters sold out. So don't wait in the last minute if you want to go to the course. Uh you can access registration for that course either through the academy website aaot. us or you can go to ozonecourse.com and you can register for it. But you really ought to go to the course if you want to learn how to do this. That said, I wrote a book called the principles and applications of ozone therapy. There's a lot of protocols in that book. Just get it from Amazon. Okay. Dr. Celely, do you have any experience using highdosese IV vitamin C plus DMSO? No, not at all. Oh, okay. Easy question. We might uh we can talk uh Virginia will be back on the stage this afternoon. That question might be relevant there. And what about uh using ozone in HIV patients? Yeah, you know, uh, ozone has, um, HIV, I don't want to make this too long an answer, but, uh, the problem with HIV patient, one of the problems with HIV patients is they have a shift from their TH1 immune regulated mechanism to a TH2 immune regulated mechan mechanism. And this creates a ton of antibodies and immune complexes and makes them sick and gives them inflammation. It's a big-time problem, gives them fevers and such. You can absolutely turn that around with ozone. So, you're not going to cure them, but you will make them feel a lot better. Uh, and the disease will pretty much stop a lot of its progression, and it tandemss in real nicely with the antiviral uh, medications. Question about polyenva, giving it IV, and does it work similar to lapoic acid in upregulating the mitochondrial function of the cancer cells such that they they start using oxygen and start to have more apoptosis. Is that theoretically the mechanism of polymbba or is it what what's your thoughts on polymbba? Anyone? Um I've used poly mva for for quite a while. I have to say I'm not so sure it's all that great. Um I like I do the RGCC test and it tests for poly. Um I don't know how they test it. I don't know how they determine uh if it's if it's that efficacious. they usually give it a say at best maybe a 30% rating of efficacy whereas the chemo drugs are you know 78 82% efficacy. Um so I have to say I'm not I'm not so sure it's that that great but sometimes I just use it just because it comes up on the test and it seems like good idea. Okay, here's a question about uh how do you balance improve thyroid function if you don't use traditional blood tests? And I for that person who's asking the test and I don't know how you feel about this Frank or or Dr. Sely uh I think the new thing as far as the the I I as as Dr. Broa Barnes used to say he wouldn't give a nickel for a carload of the usual thyroid test. I think we might have something better now in terms of measuring the free T3 reverse T3 ratio which I alluded to in my presentation. Uh but generally how do you assess thyroid function when you're dealing with uh your cancer patients? H that's a good one. Okay. In general, I'm of the opinion that uh measuring hormone levels, and I don't care what hormone level you're measuring, luteinizing hormone, testosterone, T3, I don't care what it is, in general, measuring hormone levels is an absolutely poor way to diagnose who needs a hormone. The ranges are gigantic. So unless you're at the top end of the range, you don't know if you're getting enough. The other thing is remember hormones by and large work with the cellular membrane receptors. So if you have a ton of cell membrane receptors and not much hormone, you get a good effect from the hormone. If you have a huge amount of hormone and very few receptors, you get a lousy effect from the hormone. And you can't measure the receptors. So there's an unknown in there. Uh so basically my my advice to anybody would be if you're going to diagnose a hormone deficiency in your patient, don't use a lab test to do it. Just diagnose it clinically. Now with thyroid, I like to do basal metabolic rates. So that equipment I was just talking to you about a few minutes ago gives me a basal metabolic rate. And I like to do those maybe every six weeks on my cancer patients. and I'll keep pushing the thyroid and I'm seeing what happens on the metabolic rate. Now, I do use hormone tests to follow my therapy. In other words, if they have a testosterone level of say 400 and I give them testosterone, I want to see where, you know, did I give is their level now 2,000? So, you know, I want to follow it that way. Uh, but I don't ever believe you ought to use a hormone level of any kind, saliva, blood, urine, whatever to diagnose who should and shouldn't get a hormone. Specifically with thyroid, I I like never have a problem if I just use a bas metabolic rate. I want the basal metabolic rate to be at least 90% of predicted using what's called the lusk formula, which is a formula that goes all the way back to the 30s, by the way. And if they're over if they're at 90% I'm a happy guy and I don't get any problems with them. A lot of my patients with cancer down done down in the low 70s if not the 60s. And I I would encourage all of you if you don't have that equipment, a reverse T3 is becoming available in just about any lab. And just looking at that alone will tell you most of the people who have insulin resistance, fatigue, cancer, just about any kind of chronic illness will have an elevated reverse T3. And then when you throw in the T3 ratio in there, that gives you an even better way of looking at it. And any therapy that you do that improves their oxygen utilization, you'll often see the reverse T3 coming down and you can watch the free T3, it may come up, but it's the ratio that really counts. Uh, and then they'll tell you that they're feeling better. The other thing I'd like to just comment about hormone therapy too is there's so many other variables that enter into the picture. A lot of people who are using the troies or lozenes, they're not using them properly. They're swallowing it. they're upregulating their uh thyroid binding globulin, their sex hormone binding globbulin. So you have higher binding globbulins. So you're not even getting the hormone even though you have a better total. uh you may you may not have very good free and so there there's a lot of pitfalls in hormone management and I I really think you have to get to know your patients and some of the things the main reason to measure hormones is to make sure you don't have someone that's taking too much in an effort to get an extraordinary result I tell people that hormones are to help you feel normal not extraordinary just and normal for a lot of people is extraordinary but if you can do that safely that's your best way of using natural hormone therapy. Uh can what about the use of uh artis artisinate? Are you using artisinate or resveratrol or any of the uh or either one of you if you have a comment on those? Uh those are new therapies that are being introduced for cancer patients. Comment we don't use either of those two as far as IV therapy. I know our testate there's a lot of um there's some good data coming out of uh Seattle uh that seems that the combination of artate with IV vitamin C is providing some benefit um particularly again for more advanced cancer cases. So we're looking at doing this but we're not doing it yet. So ditto ditto. Okay. I'm I think we're kind of got most of the questions covered here. Does anyone have any questions from the floor that we would you would like to direct? Yes. Um, you identified the common pattern was your patients with your approaches got extraordinary results, better quality of life and then they died anyway so to speak uh with kind of a rapid downhill course but they died I assume most likely of their cancers. So question I had is what is your understanding of what's happening there? Why that pattern? And it seems to me um there must be there's some that opens the door to well what's missing? Why is this pattern happening and what might we add to get to to change that pattern? Oh boy, that's something I thought about. Huh. Um, so there there gets to be a point where you're beyond repair. That's all I can say. And certainly, uh, when you treat cancer depending on what it's blocking it, you could have have a blocking process of the portal vein or, you know, some duct or some artery or something, you're going to have some problems based upon that. And even when the cancer goes away, the scar creates a problem. So my my theory is that number one um it's it's almost impossible to literally stop the process to the point that the patient's going to live forever and not have and not die of the cancer. I have just not seen that happen in my practice. Uh what we can do is slow it down. We can minimize the clinical effects of it. But in terms of taking an advanced uh cancer patient and quote curing them of the disease, it's happened. I've done it a few times. I think one or two of those patients I mentioned to you. But you know, there's a whole lot of patients that that didn't happen to. So I think realistically speaking, I'm just looking and then when I have that conversation with the patients, I don't exclude the possibility that they could go into a full remission and even remain that way for many years. Uh, but I kind of related a little bit to what you were talking about in terms of the money. The money is a big issue. Uh, as far as, you know, I do pretty well until they run out of money, you know, that's sort of and I don't want to like cop to that. Would you you want to say something about that? Yeah. Okay. I don't want to like cop as an excuse, but it it just does seem that way. I want to say this is precisely the situation I was talking about earlier in what Dr. Joseph is established in the 50s. He had advanced metastatic cancer patients and he reported 97% of those patients had root canals or infected teeth. So this is precisely the circumstance and we all talk about something's causing oxidative stress and we're relieving oxidative stress. I guarantee you, you'll help an enormous number of those patients maintain their remissions and god forbid have cures if the dental revision is a routine part of the cancer therapy. The toxins inside root canal treated teeth, I'll tell you right now, they're present in 100% of them. They were found by Dr. Boyd Haley. All of them are on the line of toxicity as much or greater than botulinam toxin and they disseminate throughout the body and they absolutely assassinate the antioxidant status of your body. So this was the you can't dry off until you're out of you can't dry off while you're still in the shower. So, I strongly encourage you and over time uh we're going to try to get some dental therapy here at the uh Rearen Clinic and make it a a larger part of the protocol, but try to find a dentist in your community. I'll do my best to help you through further educational processes with a dentist that might be open to this. We'll be having additional seminars down the road, but you will get substantially extended improvement not only in your cancer patients but in all your chronic degenerative disease patients. I think thank you Tom. I think another message here is that we are good at initiating what we know and when we have an initial response and the patient does well, we keep using that thinking this is it. And I think as clinicians with cancer patients, if we can be relentless in the search, and granted financial limitations do begin to apply, uh patients just kind of get tired. I mean, you know, no one wants to be a cancer patient. Actually, the people who go on living their lives as if they weren't cancer patients in my observation actually do better. But under the surface, they should be asking that question. What else could be going on? And I know when I see people back and they're doing better, it's kind of like pat them on the shoulder. Hey, great. Glad to hear you're doing well. Keep up the good work. And really, I should be thinking, what else might be lurking below the surface that I could get this patient interested in so they don't get into that state of the uh sub therapeutic complacency that then sets the stage for the recurrence to occur. But it that's it's in the in the world of busy clinical medicine, it just doesn't always happen. Yes. Uh, how effective is the ozone sauna compared to uh how effective systemically is the ozone sauna compared to a major therapy? Uh, we had a a fellow by the name of um u was gosh darn it um Victor Marcilio Vega. Oh Victor, you know you know him. Okay. So, uh, he's been using ozone a lot in in his work and he has he presented the academy two years ago and, uh, you know, really had some remarkable data, uh, on on a lot of advanced cancer patients. And he's he's he's doing like what most of us are doing. He's incorporating everything in there from vitamin C to chemo to whatever. And uh, and he's big on the saunas. Really big on the saunas. He he even made his own special sauna, which is different than the sauna all the rest of us use. all the rest of us basically uh it's it's like a a steam chamber. You're sitting in the steam chamber and then you pulse ozone gas into that chamber periodically like for five minutes every 10 minutes or something like that. So that your ozone gas is is touching on a vasoddilated moist skin and creating peroxides in the skin. Where are all the dendritic cells in your body? Mostly in the skin, right? So so uh so you it is a dendritic cell treatment. I look at it that way and I think to myself, it's probably got properties to it that the blood treatment doesn't have. Uh, obviously, it's easy to tolerate. There's no IVs. You can give it to little Stevie, the autistic kid. It's a no-brainer in that way, and it might be very beneficial. Marcel Vega, what he did is he created one where he's got this gigantic system that ozenates the water and then they sit in there and they get continually sprayed with heavily ozenated water. It's a different kind of system. Uh and he does that quite frequently like every day and uh I don't have any hard data and neither does he and there just is there actually is some hard data on the use of saunas with athletes and so you can see their V2s improve. So we know something systemically is going on that way. Uh but I have to say clinically speaking I think that it's a very valuable thing that people might want to do. We have one in the clinic. It's easy enough to do. infrared. No, this is an ozone steam sauna. It's not an infrared sauna. So, they sit in a steam box with their little head sticking out the top. It steams up in there and there's a unit that pul pulses ozone gas into there while they while they're steamed up in there. Um, I'm sorry. We're going to have to take our lunch break now. I'd sure like to thank Dr. Celely and Dr. Shaenburgger. I think it was a fabulous morning. And I want to just kind of give you keep in mind that you need to check out between 12 and 1. They will keep your things at the uh front desk. Uh we will at 1:00. Now we're coming back today a little earlier than what we did before. 1:00 uh we're going to have Michael Gonzalez and Jorge Miranda talking to us about the variables that impact the clinical effectiveness of IVC and cancer care. And then we'll have a couple panels this afternoon after that. So