Document text
Principal Investigator: Michael G Anderson
Organization: UNIVERSITY OF IOWA
Fiscal Year: 2024
Award: $179,813
Funding agency: National Eye Institute
PROJECT SUMMARY
The goal of the Rodent Phenotyping Core (RPC) is to increase the utility of mice and rats as
model organisms for vision research at The University of Iowa. The availability of a centralized
core for phenotyping will allow investigators to focus their resources on the science and
discoveries underlying vision research, rather than on training each lab’s personnel to perform
phenotyping. Such core-based services will yield more consistent and reproducible
phenotyping measures and in turn maximize the power of NEI-funded investigators to make
new discoveries.
The RPC will have the capability to perform detailed phenotyping of the anterior segment (slit-
lamp examination and photography, SD-OCT, gonioscopy, fluorescein angiography, and
intraocular pressure recording) and the posterior segment (fundus examination/photography,
electroretinogram, pupil light reflex, behavioral measurements of vision, acute suppression of
activity by light, and testing of optokinetic response).
Terms: <Acute><Address><Animal Husbandries><Animal Husbandry><Anterior><Area><Assay><Axon><Bioassay><Biological><Biological Assay><Body Tissues><COVID-19><CV-19><Categories><Collaborations><Common Rat Strains><Consult><Consultations><Coronavirus Infectious Disease 2019><Cranial Nerve II><Development><Dissection><Educational workshop><Electroretinography><Experimental Designs><Eye diseases><Fees><Fluorescein Angiography><Funding><Fundus><Goals><Gonioscopy><Housing><Human Resources><Illumination><Injections><Intraocular Pressure><Investigation><Investigators><Iowa><Light><Lighting><Manpower><Measures><Mice><Mice Mammals><Mission><Modeling><Murine><Mus><NIH><National Institutes of Health><Ocular Tension><Optic Nerve><Phenotype><Photography><Photoradiation><Physiologic Intraocular Pressure><Procedures><Pupil light reflex><Rat><Rats Mammals><Rattus><Reproducibility><Research Personnel><Research Resources><Researchers><Resources><Retina><Retinal Ganglion Cells><Rodent><Rodentia><Rodents Mammals><Science><Second Cranial Nerve><Services><Sight><Slide><System><Temperature><Testing><Tissues><Training><United States National Institutes of Health><Universities><Vision><Vision Tests><Vision research><Workshop><automated image analysis><behavior measurement><behavioral measure><behavioral measurement><biologic><consultation><consults><coronavirus disease 2019><coronavirus disease-19><coronavirus infectious disease-19><deep learning><deep learning method><deep learning strategy><developmental><electroretinogram><equipment acquirement><equipment acquisition><equipment investment><equipment procurement><equipment purchase><equipment purchasing><experiment><experimental research><experimental study><experiments><eye disorder><instrument acquisition><instrument investment><instrument procurement><instrument purchase><intra-ocular pressure><investigator training><model organism><multidisciplinary><ocular disease><ocular disorder><ophthalmopathy><pandemic><pandemic disease><personnel><pupillary light reflex><pupillary reflex><response><retinal ganglion><semen cryopreservation><sperm cell cryopreservation><sperm cryopreservation><sperm freezing><spermatozoa cryopreservation><vision science><visual function><visual science>