Document text
Principal Investigator: Paul A. Goepfert
Organization: UNIVERSITY OF ALABAMA AT BIRMINGHAM
Fiscal Year: 2024
Award: $329,189
Funding agency: National Institute of Allergy and Infectious Diseases
Modified Project Summary/Abstract Section
The mission of the Developmental Core (Dev Core) of the University of Alabama at Birmingham (UAB) CFAR is to develop early-stage investigators (ESI) in HIV research and support mid- and senior career investigators who are new to HIV (NHI). Over the past 35 years of the CFAR, we have successfully carried out this mission in alignment with the changing landscape of HIV research. Early in CFAR history, the Dev Core focused on supporting ESI/NHI developing a career in basic science at a time when little was understood about HIV pathogenesis. With the discovery of successful antiretroviral therapies, we have been expanding our support of ESI/NHI to include ESI/NHI whose research focused on treatment optimization. Most recently our core has adapted again in response to new NIH priority research areas by supporting investigators who conduct implementation science and community engaged research. Thus, at the moment, we fully support all investigators across the breadth of research from bench to bedside to community. Our success during the past 10 years is exemplified by our investment of $555K in pilot awards for 23 ESI, with 11 of them having obtained extramural funding totaling $9.5M, yielding a 17-fold increase in returns.
In the next funding cycle, we will thrive while carrying out our mission through 3 specific aims:
1) We will provide supported research funding opportunities through pilot awards to a representative cadre of ESI and NHI conducting research spanning the bench to bedside to community, and position investigators to successfully apply for extramural funding and formulate their independent research portfolios.
2) We will provide individualized mentorship to ESI and NHI to optimize their acquisition of research skills, professional development, and foster their transition to independent HIV scientists.
3) We will support professional development and networking activities, leveraging the CFAR Cores and SWGs and the larger UAB research and training community, to support ESI and NHI to build collaborative teams and innovate with a wide ranging assembly of investigators, community partners, and research networks.
Overall, the Dev Core has been extremely successful in supporting HIV-focused ESI and fostering a nurturing research environment since its inception, especially in the current funding cycle. Combined with continued successful recruitment of established investigators and ESI, the Dev Core is poised to continue its legacy of providing foundational support to HIV researchers as they launch their careers and establish themselves as independent HIV researchers.
Terms: <2019 novel corona virus><2019 novel coronavirus><2019-nCoV><AIDS><AIDS Virus><Acquired Immune Deficiency><Acquired Immune Deficiency Syndrome><Acquired Immune Deficiency Syndrome Virus><Acquired Immunodeficiency Syndrome><Acquired Immunodeficiency Syndrome Virus><Affect><Alabama><Area><Award><Basic Research><Basic Science><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 era><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 period><COVID-19 public health crisis><COVID-19 virus><COVID-19 years><COVID19 virus><Clinical><Clinical Research><Clinical Sciences><Clinical Study><CoV-2><CoV2><Collaborations><Communities><Development><EXTMR><Educational workshop><Emerging infection><Environment><Epidemic><Extramural><Extramural Activities><Faculty><Financial Support><Fostering><Funding><Funding Opportunities><Grant><HIV><HIV diagnosis><Height><History><Human Immunodeficiency Viruses><Investigators><Investments><LAV-HTLV-III><Laboratories><Learning><Lymphadenopathy-Associated Virus><Mentors><Mentorship><Methods><Mission><NIH><National Institutes of Health><Pathogenesis><Persons><Position><Positioning Attribute><Prevention><Process><Program Development><Recording of previous events><Research><Research Personnel><Research Priority><Research Support><Researchers><SARS corona virus 2><SARS-CO-V2><SARS-COVID-2><SARS-CoV-2><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-CoV2><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Science><Scientist><Severe Acute Respiratory Coronavirus 2><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome related corona virus 2><Strategic Planning><Structure><Time><Training><Underrepresented Ethnic Minority><Underrepresented Minority><United States National Institutes of Health><Universities><Virus-HIV><Woman><Work><Workshop><Writing><Wuhan coronavirus><antiretroviral therapy><antiretroviral treatment><bench bed side><bench bedside><bench to bed side><bench to bedside><bench to clinic><bench to clinical practice><career><career development><cohort><community building><community engaged participatory research><community engaged research><community engagement><community partnered research><community partners><community-based partners><community-engaged study><community-partnered study><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><coronavirus disease-19 global pandemic><coronavirus disease-19 pandemic><coronavirus disease-19 virus><developmental><emergent infection><engagement with communities><financial assistance><graduate student><hCoV19><histories><implementation science><innovate><innovation><innovative><interest><investigator training><nCoV2><next generation><novel><programs><public health emergency><recruit><response><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><skills><success><synergism><therapy optimization><treatment optimization><under-representation of minorities><under-represented minority><undergrad><undergraduate><undergraduate student><underrepresentation of minorities><virology><work group><working group>