Project 3 - Ex vivo immune profiling of dengue viruses and vaccines

NIH Pandemic-Era Grants

Pandemic Era Grants

2021

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Principal Investigator: Ana  Fernandez-Sesma
Organization: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Fiscal Year: 2021
Award: $152,665
Funding agency: National Institute of Allergy and Infectious Diseases

The COVID-19 pandemic is the most important health challenge to the US population within a
century. Most epidemiological data have focused on cases that resulted in severe respiratory
disease seen predominantly in adults. Inadequate information regarding the infection burden in
children is available, especially in the context of households that are prospectively monitored
with repetitive testing. This information is critical to determine the silent and symptomatic
infection rate in children. The NIAID-supported Human Epidemiology and Response to SARS-
CoV-2 (HEROS) survey study is designed to fill this gap.

Terms: <0-11 years old><2019 novel corona virus><2019 novel coronavirus><2019-nCoV><21+ years old><Address><Administrative Supplement><Adult><Adult Human><COVID crisis><COVID epidemic><COVID pandemic><COVID-19 crisis><COVID-19 epidemic><COVID-19 global health crisis><COVID-19 global pandemic><COVID-19 health crisis><COVID-19 pandemic><COVID-19 public health crisis><COVID-19 virus><COVID19 crisis><COVID19 epidemic><COVID19 global health crisis><COVID19 global pandemic><COVID19 health crisis><COVID19 pandemic><COVID19 public health crisis><COVID19 virus><Child><Child Youth><Children (0-21)><CoV-2><CoV2><DENV vaccine><Dengue Vaccine><Dengue virus vaccine><Enrollment><Epidemiological data><Epidemiology><Epidemiology data><Funding><Health><Household><Human><Immune><Immunes><Lung diseases><Modern Man><Monitor><NIAID><NIH><National Institute of Allergy and Infectious Disease><National Institutes of Health><Participant><Pediatric Research><Population><Pulmonary Diseases><Pulmonary Disorder><Respiratory Disease><Respiratory System Disease><Respiratory System Disorder><SARS corona virus 2><SARS-CoV-2><SARS-CoV-2 epidemic><SARS-CoV-2 global health crisis><SARS-CoV-2 global pandemic><SARS-CoV-2 pandemic><SARS-CoV2><SARS-CoV2 epidemic><SARS-CoV2 pandemic><SARS-associated corona virus 2><SARS-associated coronavirus 2><SARS-coronavirus-2><SARS-coronavirus-2 epidemic><SARS-coronavirus-2 pandemic><SARS-related corona virus 2><SARS-related coronavirus 2><SARSCoV2><Serology><Severe Acute Respiratory Distress Syndrome CoV 2><Severe Acute Respiratory Distress Syndrome Corona Virus 2><Severe Acute Respiratory Distress Syndrome Coronavirus 2><Severe Acute Respiratory Syndrome CoV 2><Severe Acute Respiratory Syndrome CoV 2 epidemic><Severe Acute Respiratory Syndrome CoV 2 pandemic><Severe Acute Respiratory Syndrome-associated coronavirus 2><Severe Acute Respiratory Syndrome-related coronavirus 2><Severe acute respiratory syndrome associated corona virus 2><Severe acute respiratory syndrome corona virus 2><Severe acute respiratory syndrome coronavirus 2><Severe acute respiratory syndrome coronavirus 2 epidemic><Severe acute respiratory syndrome coronavirus 2 pandemic><Severe acute respiratory syndrome related corona virus 2><Survey Instrument><Surveys><Testing><United States National Institutes of Health><Wuhan coronavirus><adulthood><burden of infection><corona virus disease 2019 epidemic><corona virus disease 2019 pandemic><coronavirus disease 2019 crisis><coronavirus disease 2019 epidemic><coronavirus disease 2019 global health crisis><coronavirus disease 2019 global pandemic><coronavirus disease 2019 health crisis><coronavirus disease 2019 pandemic><coronavirus disease 2019 public health crisis><coronavirus disease 2019 virus><coronavirus disease crisis><coronavirus disease epidemic><coronavirus disease pandemic><design><designing><disease of the lung><disorder of the lung><enroll><epidemiologic><epidemiologic data><epidemiological><hCoV19><infection burden><infection rate><lung disorder><member><nCoV2><prospective><rate of infection><research study><response><severe acute respiratory syndrome coronavirus 2 global health crisis><severe acute respiratory syndrome coronavirus 2 global pandemic><youngster>