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Principal Investigator: Susan H. Yoon
Organization: OHIO STATE UNIVERSITY
Fiscal Year: 2024
Award: $170,963
Funding agency: National Institute on Drug Abuse
PROJECT SUMMARY/ABSTRACT
Susan Yoon, PhD, MSW, is a social scientist whose overarching career goal is to prevent substance use and
improve health outcomes among vulnerable, at-risk youth by identifying key mechanisms for risk and resilience
to adolescent substance use following child maltreatment. This K01 Mentored Research Scientist Development
Award will provide Dr. Yoon with rigorous training and systematic mentored research experiences that will
accelerate her successful transition to an independent investigator in the field of adolescent substance use
research. A team of highly qualified and committed mentors, who are prominent researchers in their respective
fields, will guide and supervise her K01 research and training activities. The proposed career development plan
encompasses four hands-on training goals to improve her knowledge and skills in: 1) adolescent substance
use research with vulnerable youth; 2) the use of contextual/spatial (i.e., activity space) data; 3) the application
of the resilience framework; and 4) advanced statistics, including person-centered analysis, multi-level
modeling, and spatial analysis. During the K01 award period, Dr. Yoon will obtain and apply these new skills
and knowledge to address important questions about the complex associations among child maltreatment,
youth activity spaces—refers to areas or places a person visits in daily routine—and adolescent substance
use. Child maltreatment and adolescent substance use are two serious, tightly connected public health
concerns. Despite the well-established link between these phenomena, the underlying mechanisms and
moderators (protective factors) of this link remains elusive, significantly hampering our ability to effectively
prevent adolescent substance use. Thus, the proposed study aims to: 1) examine how distinct patterns of
longitudinal maltreatment experiences are associated with different patterns of adolescent substance use
trajectories; 2) investigate the mediating effects of risky attributes within youth's activity spaces on the
association between child maltreatment and adolescent substance use; and 3) determine the extent to which
protective attributes within youth's activity spaces buffers the impact of child maltreatment on substance use
during adolescence. To address the study aims, Dr. Yoon will employ creative integration and analysis of
diverse data sources, including data linkage between administrative child welfare records and geo-coded youth
spatial exposure data. The study also introduces theoretical innovation through the integration of resilience
theory and novel spatially-situated protective factors to understand resilience to substance use following child
maltreatment. This study directly addresses NIDA's research priorities and strategic goals of supporting
research to understand the complex interactions of environmental, behavioral, and social factors influencing
drug use trajectories. Findings will offer valuable insight into key contextual mechanisms and protective factors
that can be targeted in interventions to prevent substance use among high-risk, vulnerable youth.
Terms: <0-11 years old><12-20 years old><Acceleration><Address><Adolescence><Adolescent><Adolescent Development><Adolescent Youth><Area><Behavioral><Buffers><Child><Child Abuse and Neglect><Child Welfare><Child Youth><Childhood maltreatment><Children (0-21)><Chronic><Communities><Complex><County><Creativeness><Data><Data Linkages><Data Sources><Data Systems><Development><Development Plans><Differences between sexes><Differs between sexes><Doctor of Philosophy><Drug usage><Drugs><Environmental Exposure><Exposure to><Fostering><Gender><Goals><Health><IT Systems><Individual><Information Systems><Information Technology Systems><Intervention><Intervention Strategies><Investigation><Investigators><K01 Award><K01 Mechanism><K01 Program><Knowledge><Learning><Life Cycle><Life Cycle Stages><Link><Location><Long-term cohort study><Longitudinal Studies><Longitudinal cohort study><Longterm cohort study><Mediating><Medication><Mental Depression><Mentored Research Scientist Development Award><Mentored Training Award><Mentors><Methodology><NIDA><National Institute of Drug Abuse><National Institute on Drug Abuse><Ohio><Outcome><Pathway interactions><Pattern><Persons><Ph.D.><PhD><Pharmaceutical Preparations><Play><Prevention><Public Health><Qualifying><Record Linkage Study><Records><Research><Research Activity><Research Personnel><Research Priority><Research Scientist Development Award><Research Support><Researchers><Risk><Risk Factors><Role><Scientist><Sex Differences><Sexual differences><Shapes><Site><Social Controls><Substance Addiction><Substance Dependence><Substance Use Disorder><Training><Training Activity><Trauma><Trust><United States><Violence><Visit><Work><Youth><Youth 10-21><adolescence (12-20)><adolescent health><adolescent substance use><adolescent trauma><adolescent welfare><behavioral health><build resilience><build resiliency><career><career development><child maltreatment><child well being><child wellbeing><childhood trauma><co-morbid><co-morbidity><comorbidity><creativity><data diversity><depression><develop resilience><develop resiliency><developmental><diverse data><drug use><drug/agent><effective intervention><enhance resilience><enhance resiliency><experience><high risk><improve resilience><improve resiliency><improved><increase resilience><increase resiliency><innovate><innovation><innovative><insight><interventional strategy><juvenile><juvenile human><kids><life course><long-term study><longitudinal outcome studies><longterm study><maltreatment><methods to study multiple-level influences><mistreatment><multi-level analysis><multi-level model><multilevel analysis><multilevel model><multilevel modeling><multiple data sources><multiple substance use><multisubstance use><novel><pathway><pediatric trauma><person centered><poly substance use><polysubstance use><polyvictimization><prevent><prevent substance use><preventing><promote resilience><promote resiliency><protective factors><psychosocial><resilience><resilience development><resilient><sex based differences><sex-dependent differences><sex-related differences><sex-specific differences><skills><social><social factors><social role><statistics><substance use><substance use among adolescents><substance use among youth><substance use and disorder><substance use prevention><substance using><theories><training module><trauma in children><trauma symptom><violent><violent behavior><willingness><youngster><youth substance use>